Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Catherine, Uyttenhove"'
Autor:
Aditi Gupta, Sadna Budhu, Kelly Fitzgerald, Rachel Giese, Adam O. Michel, Aliya Holland, Luis Felipe Campesato, Jacques van Snick, Catherine Uyttenhove, Gerd Ritter, Jedd D. Wolchok, Taha Merghoub
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Gupta et al. demonstrate that targeting isoform-specific TGFβ leads to an increase in the anti-tumor response when compared to pan-TGFβ inhibition, due to enhanced CD8 T cell function. The authors also report that combining TGFβ inhibition with im
Externí odkaz:
https://doaj.org/article/ed988a10eff742c391e7da0374286113
Autor:
Mohamed F. Mandour, Pyone Pyone Soe, Catherine Uyttenhove, Jacques Van Snick, Etienne Marbaix, Jean-Paul Coutelier
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background Viral infections can reduce early cancer development through enhancement of cancer immunosurveillance. This study was performed to analyse this effect of viral infection in a mouse model of solid tumor. Methods The experimental mo
Externí odkaz:
https://doaj.org/article/aa131a45d891400d842aa29ce1cbd298
Autor:
Taha Merghoub, Sadna Budhu, Luis Felipe Campesato, Aditi Gupta, Catherine Uyttenhove, Aliya Holland, Kelly Fitzgerald, Rachel Giese, Adam Michel, Jacques Van Snick, Gerd Ritter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/b7686bae70e5419d9cb92be4956f038f
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Transforming growth factor-β (TGFβ) is emerging as a promising target for cancer therapy, given its ability to promote progression of advanced tumors and to suppress anti-tumor immune responses. However, TGFβ also plays multiple roles i
Externí odkaz:
https://doaj.org/article/d28bf02dc40c434ab23c04a1d7f2362e
Autor:
Jingjing Zhu, Céline G. Powis de Tenbossche, Stefania Cané, Didier Colau, Nicolas van Baren, Christophe Lurquin, Anne-Marie Schmitt-Verhulst, Peter Liljeström, Catherine Uyttenhove, Benoit J. Van den Eynde
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Cancer immunotherapy is ineffective in a subset of patients. Here the authors show that, in a mouse model of melanoma, resistance to immune checkpoint inhibitors relies on loss of tumor-specific T cells through FasL-mediated apoptosis triggered by po
Externí odkaz:
https://doaj.org/article/03b05d3e6ab641c1b1de96121c6dfbee
Autor:
Mélanie Gaignage, Reece G. Marillier, Perrine M. Cochez, Laure Dumoutier, Catherine Uyttenhove, Jean-Paul Coutelier, Jacques Van Snick
Publikováno v:
Haematologica, Vol 104, Iss 2 (2019)
In spite of considerable therapeutic progress, acute graft-versus-host disease still limits allogeneic hematopoietic cell transplantation. We recently reported that mouse infection with nidovirus lactate dehydrogenase elevating virus impairs disease
Externí odkaz:
https://doaj.org/article/422fcf45535c43e9a8ec9212d0bb09f3
Autor:
Jacques Van Snick, Catherine Uyttenhove, Mohamed F. Mandour, Jean-Paul Coutelier, Pyone Pyone Soe, Etienne Marbaix
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-9 (2020)
Infectious Agents and Cancer
Infectious agents and cancer, Vol. 15, p. 30 [1-9] (2020)
Infectious Agents and Cancer
Infectious agents and cancer, Vol. 15, p. 30 [1-9] (2020)
Background Viral infections can reduce early cancer development through enhancement of cancer immunosurveillance. This study was performed to analyse this effect of viral infection in a mouse model of solid tumor. Methods The experimental model used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06da22ecf140328fdf060cfc72ce341c
http://link.springer.com/article/10.1186/s13027-020-00288-6
http://link.springer.com/article/10.1186/s13027-020-00288-6
Autor:
Taha Merghoub, Aditi Gupta, Gerd Ritter, Rachel Giese, Kelly Fitzgerald, Luis Felipe Campesato, Jacques Van Snick, Sadna Budhu, Jedd D. Wolchok, Catherine Uyttenhove, Adam O. Michel, Aliya Holland
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
TGFβ is a potential target in cancer treatment due to its dual role in tumorigenesis and homeostasis. However, the expression of TGFβ and its inhibition within the tumor microenvironment has mainly been investigated in stroma-heavy tumors. Using B1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71cf929f241e8aeab4df9485fda46fb
https://doi.org/10.1038/s42003-021-02773-z
https://doi.org/10.1038/s42003-021-02773-z
Autor:
Christophe Bourdeaux, Paméla Chéou, Mohamed F. Mandour, Mélanie Gaignage, Jacques Van Snick, Lindsay L. Jones, Catherine Uyttenhove, Dario A. A. Vignali, Jean-Paul Coutelier
Publikováno v:
European Journal of Immunolgy, Vol. 51, no.6, p. 1482-1493 (2021)
The dimeric cytokine IL-12 is important in the control of various infections but also contributes to the pathology of certain diseases making it a potential target for therapy. However, its specific inhibition with antibodies is complicated by the fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edb6e6d82cf064498184496b7f1e8aa
https://pubmed.ncbi.nlm.nih.gov/33788263
https://pubmed.ncbi.nlm.nih.gov/33788263
Autor:
Christophe Bourdeaux, Paméla Chéou, Lindsay L. Jones, Mohamed F. Mandour, Catherine Uyttenhove, Jacques Van Snick, Dario A. A. Vignali, Jean-Paul Coutelier, Mélanie Gaignage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e996b304d5790a5985088ebb980c7828
https://doi.org/10.1002/eji.202048936/v2/response1
https://doi.org/10.1002/eji.202048936/v2/response1
