Synthesis of Poly(Malic Acid) Derivatives End-Functionalized with Peptides and Preparation of Biocompatible Nanoparticles to Target Hepatoma Cells

Autor: Clarisse Brossard, Manuel Vlach, Elise Vène, Catherine Ribault, Vincent Dorcet, Nicolas Noiret, Pascal Loyer, Nicolas Lepareur, Sandrine Cammas-Marion

Publikováno v: Nanomaterials, Vol 11, Iss 4, p 958 (2021)

Recently, short synthetic peptides have gained interest as targeting agents in the design of site-specific nanomedicines. In this context, our work aimed at developing new tools for the diagnosis and/or therapy of hepatocellular carcinoma (HCC) by gr

Externí odkaz: https://doaj.org/article/32df697ded4e431ca2f6d28c3224dd43

Circumsporozoite Protein of

Autor: Elise, Vène, Kathleen, Jarnouen, Catherine, Ribault, Manuel, Vlach, Yann, Verres, Mickaël, Bourgeois, Nicolas, Lepareur, Sandrine, Cammas-Marion, Pascal, Loyer

Publikováno v: Pharmaceutics. 14(4)

In order to identify the peptides, selected from the literature, that exhibit the strongest tropism towards human hepatoma cells, cell uptake assays were performed using biotinylated synthetic peptides bound to fluorescent streptavidin or engrafted o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c0638ebf43c61cad60f0e6a6729e1d75
https://pubmed.ncbi.nlm.nih.gov/35456637

Synthesis of Poly(Malic Acid) Derivatives End-Functionalized with Peptides and Preparation of Biocompatible Nanoparticles to Target Hepatoma Cells

Autor: Catherine Ribault, Elise Vene, Clarisse Brossard, Nicolas Lepareur, Pascal Loyer, Manuel Vlach, Nicolas Noiret, Sandrine Cammas-Marion, Vincent Dorcet

Publikováno v: Nanomaterials
Nanomaterials, MDPI, 2021, 11 (4), pp.958. ⟨10.3390/nano11040958⟩
Nanomaterials, 2021, 11 (4), pp.958. ⟨10.3390/nano11040958⟩
Nanomaterials, Vol 11, Iss 958, p 958 (2021)
Volume 11
Issue 4

International audience; Recently, short synthetic peptides have gained interest as targeting agents in the design of site-specific nanomedicines. In this context, our work aimed at developing new tools for the diagnosis and/or therapy of hepatocellul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6349e7e7a11e1fc61d4dbfec840c735
https://hal.archives-ouvertes.fr/hal-03223906/file/nanomaterials-11-00958.pdf

Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices

Autor: Francis Finot, Régis Masson, Fabienne Desmots, Catherine Ribault, Nicole Bichet, Joan A. Vericat, Patricia Lafouge, Christiane Guguen-Guillouzo, Pascal Loyer

Publikováno v: International Journal of Hepatology, Vol 2012 (2012)

The culture liver slices are mainly used to investigate drug metabolism and xenobiotic-mediated liver injuries while apoptosis and proliferation remain unexplored in this culture model. Here, we show a transient increase in LDH release and caspase ac

Externí odkaz: https://doaj.org/article/faeeaa5398634ad9b5bd3441fc534ab1

Synthesis of Poly(Dimethylmalic Acid) Homo- and Copolymers to Produce Biodegradable Nanoparticles for Drug Delivery: Cell Uptake and Biocompatibility Evaluation in Human Heparg Hepatoma Cells

Autor: Saad Saba, Sandrine Cammas-Marion, Pascal Loyer, Manuel Vlach, Ali Khalil, Olivier Coulembier, Catherine Ribault

Publikováno v: Polymers, Vol 12, Iss 1705, p 1705 (2020)
Polymers
Polymers, 2020, 12 (8), pp.1705. ⟨10.3390/polym12081705⟩
Polymers, MDPI, 2020, 12 (8), pp.1705. ⟨10.3390/polym12081705⟩
Volume 12
Issue 8

Hydrophobic and amphiphilic derivatives of the biocompatible and biodegradable poly(dimethylmalic acid) (PdiMeMLA), varying by the nature of the lateral chains and the length of each block, respectively, have been synthesized by anionic ring-opening

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8af305c54a9570f9b549e8114917063
https://doi.org/10.3390/polym12081705