Heptafluoroisobutyronitrile (C

Autor: Allison, Carles, Audrey, Schlernitzauer, Michel, Vignes, Gérard, Cros, Richard, Magous, Tangui, Maurice, Catherine, Oiry

Publikováno v: Toxicology. 480

Fluoronitrile gas (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a5addfd66724eae5f9a4e59fea43cf4a
https://pubmed.ncbi.nlm.nih.gov/36100137

Heptafluoroisobutyronitrile (C4F7N), a gas used for insulating and arc quenching in electrical switchgear, is neurotoxic in the mouse brain

Autor: Allison Carles, Audrey Schlernitzauer, Michel Vignes, Gérard Cros, Richard Magous, Tangui Maurice, Catherine Oiry

Publikováno v: Toxicology. 480:153319

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23fb8601632bcf15eddd78e77c8dba3d
https://doi.org/10.1016/j.tox.2022.153319

Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans.

Autor: Audrey Schlernitzauer, Catherine Oiry, Raphael Hamad, Simon Galas, Fabienne Cortade, Béatrice Chabi, François Casas, Laurence Pessemesse, Gilles Fouret, Christine Feillet-Coudray, Gérard Cros, Gérard Cabello, Richard Magous, Chantal Wrutniak-Cabello

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e78788 (2013)

Chicoric acid (CA) is a caffeoyl derivative previously described as having potential anti-diabetic properties. As similarities in cellular mechanism similarities between diabetes and aging have been shown, we explored on L6 myotubes the effect of CA

Externí odkaz: https://doaj.org/article/9fbe13c8d1bc4caab328b1b67292dbbb

Development of non-peptidic inverse agonists of the ghrelin receptor (GHSR) based on the 1,2,4-triazole scaffold

Autor: Sonia Cantel, Jean-Alain Fehrentz, Severine Denoyelle, Catherine Oiry, Gimena Fernandez, Mario Perello, Sylvie Peraldi-Roux, Jean-Louis Banères, Céline M'Kadmi, Guadalupe García Romero, Jacky Marie, Sophie Mary, Mathieu Maingot, Marjorie Damian, Anne-Laure Blayo, Jérémie Neasta, Khoubaib Ben Haj Salah

Publikováno v: Journal of Clinical Chemistry and Clinical Biochemistry
Journal of Clinical Chemistry and Clinical Biochemistry, 2020, ⟨10.1021/acs.jmedchem.9b02122⟩
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (19), pp.10796-10815. ⟨10.1021/acs.jmedchem.9b02122⟩

International audience; GHSR controls, among others, growth hormone and insulin secretion, adiposity, feeding and glucose metabolism. Therefore, an inverse agonist ligand capable of selectively targeting GHSR and reducing its high constitutive activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff4a1b5d5080c225244a11ba684780e
https://hal.archives-ouvertes.fr/hal-03023656

The ellagitannin metabolite urolithin C is a glucose-dependent regulator of insulin secretion through activation of L-type calcium channels

Autor: Daniele Del Rio, Guillaume Gautheron, Jean-François Guichou, Gérard Cros, Catherine Oiry, Richard Magous, Morgane Bayle, Estelle Youl, Jérémie Neasta, Jean-François Quignard, Alan Crozier, Anne Virsolvy, Margherita Dall'Asta

Publikováno v: Br J Pharmacol
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2019, ⟨10.1111/bph.14821⟩
British Journal of Pharmacology, 2019, ⟨10.1111/bph.14821⟩

BACKGROUND AND PURPOSE: The pharmacology of polyphenol metabolites on beta‐cell function is largely undetermined. We sought to identify polyphenol metabolites that enhance the insulin‐secreting function of beta‐cells and to explore the underlyi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e12b21006b68d4f41606fe126fa137
https://pubmed.ncbi.nlm.nih.gov/31378934