Výsledky vyhledávání - "Catherine, Julie"

Akademický článek

Role of antibiotic use, plasma citrulline and blood microbiome in advanced non-small cell lung cancer patients treated with nivolumab

Autor: Julia Ouaknine Krief, Pierre Helly de Tauriers, Coraline Dumenil, Nathalie Neveux, Jennifer Dumoulin, Violaine Giraud, Sylvie Labrune, Julie Tisserand, Catherine Julie, Jean-François Emile, Thierry Chinet, Etienne Giroux Leprieur

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)

Abstract Background Recent data suggested a role of gut microbiota and antibiotic use on immune checkpoint inhibitors efficacy. We aimed to evaluate the impact of early use of antibiotic (EUA), blood microbiome and plasmatic citrulline (marker of the

Externí odkaz: https://doaj.org/article/1ac16da7d72d4360a71cc08abea4aa14

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Akademický článek

Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression

Autor: Jean-François Emile, Coraline Dumenil, Jennifer Dumoulin, Violaine Giraud, Sylvie Labrune, Catherine Julie, Thierry Chinet, Etienne Giroux Leprieur, Zofia Hélias-Rodzewicz, Paul Takam Kamga, Adrien Costantini, Alexandre Corjon, Simon Garinet

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

Background Despite prolonged tumor response to immune checkpoint inhibitors (ICIs) for a subset of patients with advanced non-small cell lung cancer (NSCLC), a secondary resistance will occur for a majority of these patients. The understanding of lat

Externí odkaz: https://doaj.org/article/03dd415e5a6e46c3a728013a99b7763e

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Akademický článek

Predictive role of plasmatic biomarkers in advanced non-small cell lung cancer treated by nivolumab

Autor: Adrien Costantini, Catherine Julie, Coraline Dumenil, Zofia Hélias-Rodzewicz, Julie Tisserand, Jennifer Dumoulin, Violaine Giraud, Sylvie Labrune, Thierry Chinet, Jean-François Emile, Etienne Giroux Leprieur

Publikováno v: OncoImmunology, Vol 7, Iss 8 (2018)

Immune checkpoint inhibitors, as nivolumab, are used in advanced non-small cell lung cancer (NSCLC). However, no associated biomarker is validated in clinical practice with this drug. We investigated herein immune-related blood markers in patients wi

Externí odkaz: https://doaj.org/article/da287e26617f4bc5a35c7d66a6731c6a

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Akademický článek

Circulating tumor DNA evaluated by Next-Generation Sequencing is predictive of tumor response and prolonged clinical benefit with nivolumab in advanced non-small cell lung cancer

Autor: Etienne Giroux Leprieur, Guillaume Herbretau, Coraline Dumenil, Catherine Julie, Violaine Giraud, Sylvie Labrune, Jennifer Dumoulin, Julie Tisserand, Jean-François Emile, Hélène Blons, Thierry Chinet

Publikováno v: OncoImmunology, Vol 7, Iss 5 (2018)

Nivolumab is an anti-PD1 antibody, given in second-line or later treatment in advanced non-small cell lung cancer (NSCLC). The objective of this study was to describe the predictive value of circulating tumor DNA (ctDNA) on the efficacy of nivolumab

Externí odkaz: https://doaj.org/article/b85a14a64db44194ab6d9474fb505465

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Akademický článek

Fatal Haemoptysis Associated with Dramatic Response to Crizotinib in an ALK-Rearranged Lung Adenocarcinoma

Autor: Elodie Mussat, Violaine Giraud, Catherine Julie, Thierry Chinet, Etienne Giroux Leprieur

Publikováno v: Journal of Clinical and Diagnostic Research, Vol 10, Iss 3, Pp XD01-XD03 (2016)

The presence of an ALK (Anaplastic Lymphoma Kinase) rearrangement is a rare molecular feature in Non-Small Cell Lung Carcinoma (NSCLC), and concerns mainly non- or light smokers, young patients, with adenocarcinoma histological type. These tumours a

Externí odkaz: https://doaj.org/article/4fa15762cb024c5cbc7c8308b2e207dd

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Revisiting immune escape in colorectal cancer in the era of immunotherapy

Autor: Hans Morreau, Marieke E. Ijsselsteijn, Catherine Sautès-Fridman, Florent Petitprez, Noel Filipe da Cunha Carvalho de Miranda, Ruud van der Breggen, Laetitia Lacroix, Catherine Julie, Wolf H. Fridman, Dina Ruano

Publikováno v: British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2019, 120 (8), pp.815-818. ⟨10.1038/s41416-019-0421-x⟩
British Journal of Cancer, 120(8), 815-818. NATURE PUBLISHING GROUP

International audience; In colorectal cancer (CRC), T-cell checkpoint blockade is only effective in patients diagnosed with mismatch repair-deficient (MMR-d) cancers. However, defects in Human Leukocyte Antigen (HLA) class I expression were reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c593d6aa16f3a502cbd1be8edc62360e
https://doi.org/10.1038/s41416-019-0421-x

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CARMN-NOTCH2 fusion transcript drives high NOTCH2 expression in glomus tumors of the upper digestive tract

Autor: Janick Selves, Jean-François Emile, Marie Laure Raffin-Sanson, Benoǐt Terris, Chiara Villa, Nicolas Girard, Jérôme Cros, Catherine Julie, Jean François Fléjou, Zofia Hélias-Rodzewicz, Jean Michel Coindre, Christine Lagorce-Pages, Anne Sophie de Lajarte-Thirouard, Nathalie Guedj, Florence Renaud, Dominique Cazals-Hatem, Simon Martin de Beauce, Cristi Marin, Henri Jean Garchon

Publikováno v: Genes, Chromosomes and Cancer
Genes, Chromosomes and Cancer, Wiley, 2021, 60 (11), pp.723-732. ⟨10.1002/gcc.22981⟩
Genes, Chromosomes & Cancer
Genes, Chromosomes & Cancer, 2021, 60 (11), pp.723-732. ⟨10.1002/gcc.22981⟩

International audience; Glomus tumors (GTs) are perivascular tumors mostly occurring in the distal extremities. Rare cases arise in the digestive tract and may be misdiagnosed with neuroendocrine or gastrointestinal stromal tumors. We aimed to specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3dbe72d7e34942aae589121a0f893b
https://hal.archives-ouvertes.fr/hal-03434935

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Baseline hedgehog pathway activation and increase of plasma wnt1 protein are associated with resistance to immune checkpoint inhibitors in advanced non-small-cell lung cancer

Autor: Thierry Chinet, Camille Mehlman, Violaine Giraud, Adrien Costantini, Coraline Dumenil, Jean-François Emile, J. Ouaknine, Jennifer Dumoulin, Etienne Giroux Leprieur, Paul Takam Kamga, Catherine Julie

Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (5), pp.1107. ⟨10.3390/cancers13051107⟩
Volume 13
Issue 5
Cancers, Vol 13, Iss 1107, p 1107 (2021)

Simple Summary Wnt and Hedgehog (Hh) pathways are associated with stemness profile and with resistance to anti-tumor therapies. Pre-clinical data have suggested a role of these pathways in resistance to immune checkpoint inhibitors (ICIs). Here we ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611ed353b97710105f7e964c5e13f05f
https://hal.archives-ouvertes.fr/hal-03171231

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Plasma Biomarkers Screening by Multiplex ELISA Assay in Patients with Advanced Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors

Autor: Jennifer Dumoulin, Adrien Costantini, Violaine Giraud, Catherine Julie, Coraline Dumenil, Thierry Chinet, Jean-François Emile, Alexandre Corjon, Martin Rottman, J. Ouaknine, Etienne Giroux Leprieur, Paul Takam Kamga

Publikováno v: Cancers
Cancers, Vol 13, Iss 97, p 97 (2021)
Cancers, MDPI, 2021, 13 (1), pp.1-12. ⟨10.3390/cancers13010097⟩
Cancers, MDPI, 2021, 13 (1), pp.97. ⟨10.3390/cancers13010097⟩
Volume 13
Issue 1

Immune checkpoint inhibitors (ICIs) are commonly used in patients with advanced non-small cell lung cancer (NSCLC). An unmet need remains for new biomarkers associated with ICIs. In this study, consecutive patients with advanced NSCLC treated with ni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f6ae4504867a2fb595613ee61eac01
https://pubmed.ncbi.nlm.nih.gov/33396187

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