Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Catherine, Curdy"'
Autor:
Nicoletta Loggia, Catherine Curdy, Fabio di Lena, Peter Wick, Kathrin Grieder, Malak Bitar, Magdalena Obarzanek-Fojt
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 107:180-190
Beyond the therapeutic purpose, the impact of drug delivery microparticles on the local tissue and inflammatory responses remains to be further elucidated specifically for reactions mediated by the host immune cells. Such immediate and prolonged reac
Long-term distribution of biodegradable microparticles in rat muscle quantified noninvasively by MRI
Autor:
Christelle Gérard, Jacques Kameni Tcheudji, Catherine Curdy, Nicolau Beckmann, Catherine Cannet
Publikováno v:
Magnetic Resonance in Medicine. 75:1736-1742
Purpose To demonstrate the feasibility of MRI to monitor longitudinally the fate of PLGA microparticles in muscle tissue after intramuscular injection in rats using standard equipment. Methods MRI was performed at different time points and until day
Chitosan/glucose 1-phosphate as new stable in situ forming depot system for controlled drug delivery
Autor:
Nicolas Anton, Marc Riemenschnitter, Catherine Curdy, Thierry F. Vandamme, Stephanie Supper, Nina Seidel, Julie Boisclair
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 88:361-373
Chitosan (CS)-based thermosensitive solutions that turn into semi-solid hydrogels upon injection at body temperature have increasingly drawn attention over the last decades as an attractive new type of in situ forming depot (ISFD) drug delivery syste
Autor:
Thierry F. Vandamme, Catherine Curdy, Marc Riemenschnitter, Nicolas Anton, Nina Seidel, Stephanie Supper
Publikováno v:
Expert Opinion on Drug Delivery. 11:249-267
Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been reported as a new type of parenteral in situ forming depot system. These free-flowing solutions at ambient temperature turn into semi-solid hydrogels after parenteral administratio
Autor:
Yi Zhang, Thomas Kissel, Bernd Ulrich Riebesehl, Moritz Beck-Broichsitter, Dafeng Chu, Catherine Curdy
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 85:1232-1237
Cholesterol esterase (CE) induced surface erosion of poly(ethylene carbonate) (PEC) and drug release from PEC under mild physiological environment was investigated. The degradation process was monitored by changes of mass and molecular weight (MW) an
Autor:
Olivia M. Merkel, Moritz Beck-Broichsitter, Nadja Bege, Damiano Librizzi, Thomas Kissel, Thomas Renette, Catherine Curdy, Thomas Endres, Holger Petersen
Publikováno v:
Macromolecular Bioscience. 12:970-978
The aim of this study is to investigate the feasibility and efficacy of PEC nanoparticles as delivery system for cancer chemotherapy. Assembly of paclitaxel-loaded nanoparticles with high loading efficiency and narrow-size distribution is successful.
Autor:
Holger Petersen, Thomas Kissel, Rainer H. Müller, Thomas Renette, Mirko Jansch, Nadja Bege, Olivia M. Merkel, Regina Reul, Catherine Curdy
Publikováno v:
Macromolecular Bioscience. 11:897-904
The goal of this study was to investigate the suitability of poly(ethylene carbonate) (PEC) nanoparticles as a novel drug delivery system, fulfilling the requirements for a long circulation time. Particles were obtained with a narrow size distributio
Long-term distribution of biodegradable microparticles in rat muscle quantified noninvasively by MRI
Autor:
Jacques, Kameni Tcheudji, Catherine, Cannet, Christelle, Gérard, Catherine, Curdy, Nicolau, Beckmann
Publikováno v:
Magnetic resonance in medicine. 75(4)
To demonstrate the feasibility of MRI to monitor longitudinally the fate of PLGA microparticles in muscle tissue after intramuscular injection in rats using standard equipment.MRI was performed at different time points and until day 28 after intramus
Publikováno v:
International journal of pharmaceutics. 465(1-2)
Macrophage induced surface degradation of poly(ethylene carbonate) (PEC) was investigated under in vitro conditions. Degradation of PEC with the MW of 41 kDa (PEC41) was slower than that of PEC with the MW of 200 kDa (PEC200). In terms of macrophage
Autor:
Thomas, Renette, Damiano, Librizzi, Thomas, Endres, Olivia, Merkel, Moritz, Beck-Broichsitter, Nadja, Bege, Holger, Petersen, Catherine, Curdy, Thomas, Kissel
Publikováno v:
Macromolecular bioscience. 12(7)
The aim of this study is to investigate the feasibility and efficacy of PEC nanoparticles as delivery system for cancer chemotherapy. Assembly of paclitaxel-loaded nanoparticles with high loading efficiency and narrow-size distribution is successful.