Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Catherina Baitzel"'
Autor:
Hella S. Brönneke, Emilio Tarcitano, Markus Heine, Peter Frommolt, Nils R. Hansmeier, Trieu-My Van, Marta Pradas-Juni, Jan Mauer, George A. Garinis, Deniz Bartsch, Sajjad Khani, Susanne Brodesser, Catherina Baitzel, Matteo Oliverio, Marcelo A. Mori, Elena Schmidt, Jens C. Brüning, Hans Hilpert, Sandra Konieczka, Jan-Wilhelm Kornfeld, Jörg Heeren
Publikováno v:
Nature Cell Biology. 18:328-336
Activation of brown adipose tissue (BAT) controls energy homeostasis in rodents and humans and has emerged as an innovative strategy for the treatment of obesity and type 2 diabetes mellitus. Here we show that ageing- and obesity-associated dysfuncti
Autor:
A. Christine Könner, Hayley T. Nicholls, Karolin Herrmanns, Ludger Scheja, Markus Stoffel, Merly C. Vogt, Cécile Haumaitre, Silvia Cereghini, Jens C. Brüning, Anna Maria Wolf, Jan-Wilhelm Kornfeld, Catherina Baitzel, Joerg Heeren, Uwe Knippschild, Jost Seibler
Publikováno v:
Nature
Nature, 2013, 494 (7435), pp.111-115. ⟨10.1038/nature11793⟩
Nature, Nature Publishing Group, 2013, 494 (7435), pp.111-115. ⟨10.1038/nature11793⟩
Nature, 2013, 494 (7435), pp.111-115. ⟨10.1038/nature11793⟩
Nature, Nature Publishing Group, 2013, 494 (7435), pp.111-115. ⟨10.1038/nature11793⟩
International audience; Insulin resistance represents a hallmark during the development of type 2 diabetes mellitus and in the pathogenesis of obesity-associated disturbances of glucose and lipid metabolism(1-3). MicroRNA (miRNA)-dependent post-trans
Publikováno v:
Molecular Biology of the Cell
Protein aggregation negatively affects key enzymes of major metabolic pathways in mitochondria. The main mitochondrial chaperones Hsp70 and Hsp60 have a limited protective effect against aggregation. In contrast, the ATP-dependent matrix protease Pim