Výsledky vyhledávání - "Cathelijne P. A. M. Kloks"

Sensitivity of 1H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol

Autor: Carol Thijssen-van Zuylen, Willem G.E.J. Schoonen, Pieter Zandberg, Martin J. Smit, G. Jean Horbach, Joop H. J. van Nesselrooij, Jan-Remt Mellema, Jack T. W. E. Vogels, Albert C. Tas, Jan-Peter H. T. M. Ploemen, Cathelijne P. A. M. Kloks

Publikováno v: Toxicological Sciences. 98:271-285

1H nuclear magnetic resonance (NMR) spectroscopy of rat urine in combination with pattern recognition analysis was evaluated for early noninvasive detection of toxicity of investigational chemical entities. Bromobenzene (B) and paracetamol (P) were a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfc337fbdadb07e10ff359f447d8713
https://doi.org/10.1093/toxsci/kfm076

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Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity

Autor: Martin J. Smit, G. Jean Horbach, Jan-Peter H. T. M. Ploemen, Willem G.E.J. Schoonen, Pieter Zandberg, Cathelijne P. A. M. Kloks, Jack T. W. E. Vogels, Albert C. Tas, Jan-Remt Mellema, Joop H. J. van Nesselrooij, Carol Thijssen-vanZuylen

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 98(1)

A procedure of nuclear magnetic resonance (NMR) urinalysis using pattern recognition is proposed for early detection of toxicity of investigational compounds in rats. The method is applied to detect toxicity upon administration of 13 toxic reference

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cc67d7b7e9bcea3ef8be7d01ca589b
https://pubmed.ncbi.nlm.nih.gov/17420222

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Akademický článek

Uniform Procedure of 1H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity.

Autor: Willem G. E. J. Schoonen, Cathelijne P. A. M. Kloks, Jan-Peter H. T. M. Ploemen, Martin J. Smit, Pieter Zandberg, G. Jean Horbach, Jan-Remt Mellema, Carol Thijssen-vanZuylen, Albert C. Tas, Joop H. J. van Nesselrooij, Jack T. W. E. Vogels

Publikováno v: Toxicological Sciences; Jul2007, Vol. 98 Issue 1, p286-286, 1p

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Akademický článek

Sensitivity of 1H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol.

Autor: Willem G. E. J. Schoonen, Cathelijne P. A. M. Kloks, Jan-Peter H. T. M. Ploemen, G. Jean Horbach, Martin J. Smit, Pieter Zandberg, Jan-Remt Mellema, Carol Thijssen-van Zuylen, Albert C. Tas, Joop H. J. van Nesselrooij, Jack T. W. E. Vogels

Publikováno v: Toxicological Sciences; Jul2007, Vol. 98 Issue 1, p271-271, 1p

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