Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Catharine J. Andresen"'
Autor:
Edwin Berryman, Isabela B Bagi, Cedo M. Bagi, David E. Zakur, Catharine J. Andresen, Chang-Ning Liu
Publikováno v:
Open Journal of Orthopedics and Rheumatology. 1:004-011
Objective: This manuscript reports the outcomes of medial meniscectomy (MM) surgery on cartilage and cortical bone strength and the reaction of cartilage and bone to intensive treatment with antiresorptive (zoledronate) and anabolic bone (PTH) therap
Autor:
Bruce L. Homer, Catharine J. Andresen, Daniel Morton, James A. Warneke, Dale L. Morris, Cedo M. Bagi, Michael A. Tones, Laurence O. Whiteley
Publikováno v:
Toxicologic Pathology. 43:411-423
Orally administered small molecule agonists of soluble guanylate cyclase (sGC) induced increased numbers of osteoclasts, multifocal bone resorption, increased porosity, and new bone formation in the appendicular and axial skeleton of Sprague-Dawley r
Publikováno v:
European Journal of Gastroenterology & Hepatology. 24:563-574
Tumor recurrence and metastasis is the most common cause of mortality in hepatocellular carcinoma (HCC) patients. Despite positive results with vascular endothelial growth factor (VEGF) inhibitors in preclinical studies using HCC xenograft models, th
Autor:
Cedo M. Bagi, Catharine J. Andresen
Publikováno v:
Cancers, Vol 2, Iss 3, Pp 1441-1452 (2010)
Cancers
Cancers
The overwhelming need to improve preclinical models in oncology has stimulated research efforts to refine and validate robust orthotopic models that closely mimic the disease population and therefore have the potential to better predict clinical outc
Publikováno v:
American Medical Journal. 1:59-70
Problem Statement: The interaction of osteoblasts and osteoclasts with cells of the immune system has been suggested as a contributing factor in the development of osteoporoses. Evidence from studies in rodents suggests that T cells play a significan
Autor:
Paul S. Changelian, Maryrose J. Conklyn, Carrie Whitney-Pickett, Kudlacz Elizabeth M, Catharine J. Andresen
Publikováno v:
European Journal of Pharmacology. 582:154-161
Janus kinase 3 (JAK-3) is a tyrosine kinase that has been shown to participate in the signaling of several cytokines that are believed to play a role in allergic airway disease, e.g. IL-2, 4 and 9. The current study describes the immunosuppressive ef
Autor:
Victor Shen, Catharine J. Andresen, Edwin Berryman, Ellen Olson, Nels Hanson, Maria R. Moalli, Cedo M. Bagi, Marlo Volberg
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 290:1005-1016
In older humans, bone elongation ceases, periosteal expansion continues, and bone remodeling remains a dominant metabolic process. An appropriate animal model of type I and type II osteoporosis would be a species with sealed growth plates and persist
Publikováno v:
Arthritis Research & Therapy
Introduction Osteoarthritis (OA) is a leading cause of disability, but despite the high unmet clinical need and extensive research seeking dependable therapeutic interventions, no proven disease-modifying treatment for OA is currently available. Due
Publikováno v:
Journal of Translational Medicine
Background To acquire the most meaningful understanding of human arthritis, it is essential to select the disease model and methodology translatable to human conditions. The primary objective of this study was to evaluate a number of analytic techniq
Publikováno v:
American Journal of Immunology. 2:40-51
Vitamin D3 is known to have immunosuppressive effects that can be beneficial for treatment of immune disorders and transplant rejection, however therapeutic application is limited due to hypercalcemia and hypercalcuria. The goal of our studies was to