Výsledky vyhledávání - "Catharine Cowan"

Akademický článek

Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice.

Autor: Rujuan Dai, Catharine Cowan, Bettina Heid, Deena Khan, Zhihong Liang, Christine T N Pham, S Ansar Ahmed

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0172105 (2017)

Estrogen, a natural immunomodulator, regulates the development and function of diverse immune cell types. There is now renewed attention on neutrophils and neutrophil serine proteases (NSPs) such as neutrophil elastase (NE), proteinase 3 (PR3), and c

Externí odkaz: https://doaj.org/article/9fa18e66d7b74f4ebf90d99c466153c8

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An Unusual Cause of Femoral Nerve Paresis in a Horse: Disseminated B Cell Lymphoma With Plasmacytoid Differentiation and Direct Neuronal Invasion

Autor: Charlotte K. Barton, Kelly L. Hughes, Catharine Cowan, Yvette S. Nout-Lomas, Brad B. Nelson

Publikováno v: Journal of Equine Veterinary Science. 126:104502

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0ac57422f8197bf0e86737c7a956a9
https://doi.org/10.1016/j.jevs.2023.104502

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Phenotypic Drift in Lupus-Prone MRL/lpr Mice: Potential Roles of MicroRNAs and Gut Microbiota

Autor: Xavier Cabana-Puig, Jacob M. Bond, Zhuang Wang, Rujuan Dai, Ran Lu, Amy Lin, Vanessa Oakes, Amy Rizzo, Brianna Swartwout, Leila Abdelhamid, Jiangdi Mao, Meeta Prakash, Constanza Sangmeister, Nathaniel Cheung, Catharine Cowan, Christopher M. Reilly, Sha Sun, S. Ansar Ahmed, Xin M. Luo

MRL/lpr mice have been extensively used as a murine model of lupus. Disease progression in MRL/lpr mice can differ among animal facilities, suggesting a role for environmental factors.We noted a phenotypic drift of our in-house colony, which was the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be5ff42dddac1f7013a7ab4630e4785
https://hdl.handle.net/10919/114561

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Low-dose 17α-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice

Autor: Catharine Cowan, S. Ansar Ahmed, Rujuan Dai, Stephen R. Werre, Bettina Heid, Michael R. Edwards, Thomas E. Cecere

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

Estrogens have been shown to regulate the immune system and modulate multiple autoimmune diseases. 17α-ethinyl estradiol (EE), a synthetic analog of 17β-estradiol, is prescribed commonly and found in oral contraceptives and hormone replacement ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b9f17bf1129df933c568233f0aa5c2
https://hdl.handle.net/10919/99583

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112 Increased neutrophils and neutrophil serine proteases in the spleens of estrogen-treated C57BL/6 mice and in several strains of spontaneous lupus-prone mice

Autor: Rujuan Dai, Sattar Ansar Ahmed, Catharine Cowan, Z Liang, Ctn Pham, Deena Khan, Bettina Heid

Publikováno v: Poster Session.

Background and aims Oestrogen, a natural immunomodulator, regulates the development and function of diverse immune cell types and has been implicated in lupus development. Methods To determine the regulatory role of oestrogen on neutrophil developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::500b81914ae62d11f9eee4bbcc096c21
https://doi.org/10.1136/lupus-2017-000215.112

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Commercial rodent diets differentially regulate autoimmune glomerulonephritis, epigenetics and microbiota in MRL/lpr mice

Autor: Thomas E. Cecere, S. Ansar Ahmed, Bettina Heid, Rujuan Dai, Xin M. Luo, Catharine Cowan, Michael R. Edwards, Qinghui Mu, Deena Khan

Publikováno v: International immunology. 29(6)

The course and severity of lupus in spontaneous murine lupus models varies among laboratories, which may be due to variations in diet, housing and/or local environmental conditions. In this study, we investigated the influence of common rodent diets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0859d044597057e2f05c38f3512c97
https://pubmed.ncbi.nlm.nih.gov/28637300

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Estrogen and Signaling in the Cells of Immune System

Autor: Catharine Cowan, S. Ansar Ahmed, Deena Khan

Publikováno v: Advances in Neuroimmune Biology. 3:73-93

Hypothalamus-pituitary-gonadal axis regulation of estrogen, which acts on reproductive tissues, is well established. However, it is also evident that estrogens physiologically act on not only reproductive tissues but also on a broad range of tissues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::914b1c2116ce4d2d38ddaad7afe06231
https://doi.org/10.3233/nib-2012-012039

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Phenotypic and functional characterization of neutrophils from lupus-prone mice (BA4P.223)

Autor: Catharine Cowan, Rujuan Dai, Bettina Heid, S. Ahmed

Publikováno v: The Journal of Immunology. 192:46.14-46.14

Neutrophils constitute a critical component of cellular immunity that eliminate infectious organisms through oxidative burst, phagocytosis and the formation of neutrophil extracellular traps (NETs). Recently it has been reported that neutrophils cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58121e613b313bbb3a838837b91714d8
https://doi.org/10.4049/jimmunol.192.supp.46.14

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