Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Catharina W Wieland"'
Autor:
Maria T Kuipers, Thomas Vogl, Hamid Aslami, Geartsje Jongsma, Elske van den Berg, Alexander P J Vlaar, Joris J T H Roelofs, Nicole P Juffermans, Marcus J Schultz, Tom van der Poll, Johannes Roth, Catharina W Wieland
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68694 (2013)
BACKGROUND: Bacterial products add to mechanical ventilation in enhancing lung injury. The role of endogenous triggers of innate immunity herein is less well understood. S100A8/A9 proteins are released by phagocytes during inflammation. The present s
Externí odkaz:
https://doaj.org/article/d716a21ffa3645ef8cb320af87d82a64
Autor:
Maria T Kuipers, Hamid Aslami, Alexander P J Vlaar, Nicole P Juffermans, Anita M Tuip-de Boer, Maria A Hegeman, Geartsje Jongsma, Joris J T H Roelofs, Tom van der Poll, Marcus J Schultz, Catharina W Wieland
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50559 (2012)
Uric acid released from injured tissue is considered a major endogenous danger signal and local instillation of uric acid crystals induces acute lung inflammation via activation of the NLRP3 inflammasome. Ventilator-induced lung injury (VILI) is medi
Externí odkaz:
https://doaj.org/article/bd7b9fb07f6d47179120fdd171ad6058
Autor:
Arie J Hoogendijk, Sander H Diks, Tom van der Poll, Maikel P Peppelenbosch, Catharina W Wieland
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18519 (2011)
BackgroundPneumonia represents a major health burden. Previous work demonstrated that although the induction of inflammation is important for adequate host defense against pneumonia, an inability to regulate the host's inflammatory response within th
Externí odkaz:
https://doaj.org/article/b42593a1cb3d4abe8ab8aa22bd22f79d
Autor:
Gerritje J W van der Windt, W Joost Wiersinga, Catharina W Wieland, Ivo C S I Tjia, Nicholas P Day, Sharon J Peacock, Sandrine Florquin, Tom van der Poll
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 8 (2010)
Melioidosis, caused by infection with Burkholderia (B.) pseudomallei, is a severe illness that is endemic in Southeast Asia. Osteopontin (OPN) is a phosphorylated glycoprotein that is involved in several immune responses including induction of T-help
Externí odkaz:
https://doaj.org/article/3ed62197ca3b40a0a084942b23fcba40
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3494 (2008)
BACKGROUND: Toll-like receptors (TLRs) have a central role in the recognition of pathogens and the initiation of the innate immune response. Myeloid differentiation primary-response gene 88 (MyD88) and TIR-domain-containing adaptor protein inducing I
Externí odkaz:
https://doaj.org/article/b0be4749788943bbbef7c73fcfcc8f10
Autor:
W Joost Wiersinga, Catharina W Wieland, Mark C Dessing, Narisara Chantratita, Allen C Cheng, Direk Limmathurotsakul, Wirongrong Chierakul, Masja Leendertse, Sandrine Florquin, Alex F de Vos, Nicholas White, Arjen M Dondorp, Nicholas P Day, Sharon J Peacock, Tom van der Poll
Publikováno v:
PLoS Medicine, Vol 4, Iss 7, p e248 (2007)
Toll-like receptors (TLRs) are essential in host defense against pathogens by virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as the most important receptor for gram-positive bacteria, while TLR4 is regarded
Externí odkaz:
https://doaj.org/article/1f5f786e628144449fc113d05e9305b0
Autor:
J. Hessels, J.M. Rensen, H.G.M. Vloedgraven, Catharina W. Wieland, Johannes Roth, J. Boer, A. Ordelman, Thomas Vogl, L.H.A. Verwoolde
Publikováno v:
British Journal of Dermatology. 168:1252-1258
Background Hidradenitis suppurativa (HS) is a chronic inflammatory and debilitating disease of the skin. No biomarkers for this disease exist. Objectives We set out to test whether angiotensin-converting enzyme (ACE), lysozyme, soluble interleukin 2
Autor:
Catharina W. Wieland, Arie J. Hoogendijk, Marcus J. Schultz, Maria T. Kuipers, Tom van der Poll
Publikováno v:
Shock (Augusta, Ga.), 38(4), 375-380. Lippincott Williams and Wilkins
Mechanical ventilation (MV) has the potential to induce lung damage in healthy lungs or aggravate existing lung injury. Polymorphonuclear neutrophil (PMN) recruitment plays an important role in driving the inflammatory response in ventilator-induced
Autor:
JanWillem Duitman, Catharina W. Wieland, Dana C. Blok, Tom van der Poll, Arie J. Hoogendijk, Joris J. T. H. Roelofs, Miriam H. P. van Lieshout
Publikováno v:
Molecular medicine (Cambridge, Mass.), 18(7), 1086-1095. Feinstein Institute for Medical Research
Bacterial pneumonia remains associated with high morbidity and mortality. The gram-positive pathogen Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. Lipoteichoic acid (LTA) is an important proinflammatory component
Autor:
Fayyaz S. Sutterwala, Paul Bresser, Catharina W. Wieland, Hamid Aslami, John R. Janczy, Richard A. Flavell, Marcus J. Schultz, Maria T. Kuipers, Alexander P.J. Vlaar, Koenraad F. van der Sluijs, Tom van der Poll, Jaklien C. Leemans, Goda Choi, Esther K. Wolthuis, Joris J. T. H. Roelofs
Publikováno v:
Anesthesiology, 116(5), 1104-15. LIPPINCOTT WILLIAMS & WILKINS
Anesthesiology, 116(5), 1104-1115. Lippincott Williams and Wilkins
Anesthesiology, 116(5), 1104-1115. Lippincott Williams and Wilkins
Background The innate immune response is important in ventilator-induced lung injury (VILI) but the exact pathways involved are not elucidated. The authors studied the role of the intracellular danger sensor NLRP3 inflammasome. Methods NLRP3 inflamma