Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Catharina Steentoft"'
Autor:
Amberlyn M Wands, Akiko Fujita, Janet E McCombs, Jakob Cervin, Benjamin Dedic, Andrea C Rodriguez, Nicole Nischan, Michelle R Bond, Marcel Mettlen, David C Trudgian, Andrew Lemoff, Marianne Quiding-Järbrink, Bengt Gustavsson, Catharina Steentoft, Henrik Clausen, Hamid Mirzaei, Susann Teneberg, Ulf Yrlid, Jennifer J Kohler
Publikováno v:
eLife, Vol 4 (2015)
Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors using its B subunit (CTB). The ganglioside (glycolipid) GM1 is thought to be the sole CT receptor; however, the mechanism by which CTB binding to GM1 mediates i
Externí odkaz:
https://doaj.org/article/3c68ba7482ae44199ba3d13b04350700
Autor:
Ricardo Coelho, Lara Marcos-Silva, Nuno Mendes, Daniela Pereira, Catarina Brito, Francis Jacob, Catharina Steentoft, Ulla Mandel, Henrik Clausen, Leonor David, Sara Ricardo
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2045 (2018)
Optimal research results rely on the selection of cellular models capable of recapitulating the characteristics of primary tumours from which they originate. The expression of mucins (MUC16 and MUC1) and truncated O-glycans (Tn, STn and T) represents
Externí odkaz:
https://doaj.org/article/8f88dcbeca1240eeb502cf13a814c99b
Autor:
Caroline B Madsen, Kirstine Lavrsen, Catharina Steentoft, Malene B Vester-Christensen, Henrik Clausen, Hans H Wandall, Anders Elm Pedersen
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72413 (2013)
Membrane bound mucins are up-regulated and aberrantly glycosylated during malignant transformation in many cancer cells. This results in a negatively charged glycoprotein coat which may protect cancer cells from immune surveillance. However, only lim
Externí odkaz:
https://doaj.org/article/d29f6a412dca4efc8e46d49fbb687bc5
Autor:
Caroline B. Madsen, Kirstine Lavrsen, Catharina Steentoft, Malene B. Vester-Christensen, Henrik Clausen, Hans H. Wandall, Anders Elm Pedersen
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/47ce4dcd4e4e4db1ac47ba1bb9e43a57
Autor:
Catharina Steentoft, Jen Jen Yeh, Hye Rim Lee, Fang Qiu, Lara Marcos-Silva, Benjamin J. Swanson, Ulla Mandel, Michael A. Hollingsworth, Kelly A. O'Connell, Xiang Liu, Fang Yu, Henrik Clausen, Hans H. Wandall, Xianlu L. Peng, Divya Thomas, Kenneth P. Olive, Satish Sagar, James A. Grunkemeyer, Paul M. Grandgenett, Thomas C. Caffrey, Hans Carlo Maurer, Prakash Radhakrishnan, Ragupathy Madiyalakan
Publikováno v:
Mol Ther
Aberrant expression of CA125/MUC16 is associated with pancreatic ductal adenocarcinoma (PDAC) progression and metastasis. However, knowledge of the contribution of MUC16 to pancreatic tumorigenesis is limited. Here, we show that MUC16 expression is a
Autor:
Katrine T. Schjoldager, Leo Alexander Dworkin, Anja Jørgensen, Adnan Halim, Henrik Clausen, Sergey Y. Vakhrushev, Hans H. Wandall, Catharina Steentoft, Hiren J. Joshi
Publikováno v:
Glycobiology. 28:131-136
The GlycoDomainViewer is a bioinformatic tool to aid in the mining of glycoproteomic datasets from different sources and facilitate incorporation of glycosylation into studies of protein structure and function. We present a version 2.0 of GlycoDomain
Autor:
Madeline Steiner, Karin Schreiber, Jonathan Zerweck, Ulla Mandel, Carl H. June, Preeti Sharma, H. Michael Shepard, Steven P. Wolf, Frank Wen, Catharina Steentoft, Hans Schreiber, Henrik Clausen, Stephen C. Meredith, Avery D. Posey, Matthias Leisegang, Yanran He, David M. Kranz
Publikováno v:
JCI insight. 4(21)
Human cancer cells were eradicated by adoptive transfer of T cells transduced with a chimeric antigen receptor (CAR) made from an antibody (237Ab) that is highly specific for the murine Tn-glycosylated podoplanin (Tn-PDPN). The objectives were to det
Autor:
Shengjun Wang, Zhang Yang, Yoshiki Narimatsu, Katrine T. Schjoldager, Christoffer K. Goth, Sarah L. King, Tongzhong Ju, Lars Hansen, Eric P. Bennett, María F Festari, Malene Bech Vester-Christensen, Ulla Mandel, Catharina Steentoft, Kelley W. Moremen, Ida Signe Bohse Larsen
Publikováno v:
Glycobiology
Complex carbohydrates serve a wide range of biological functions in cells and tissues, and their biosynthesis involves more than 200 distinct glycosyltransferases (GTfs) in human cells. The kinetic properties, cellular expression patterns and subcell
Autor:
Zhang Yang, Sanae Furukawa, Gosse J. Adema, Yen-Hsi Chen, Lars Hansen, Christian Büll, James C. Paulson, Rebecca Nason, Sergey Y. Vakhrushev, Paul M. Sullam, Hiren J. Joshi, Zilu Ye, Andrew J. Thompson, Richard Karlsson, Katrine T. Schjoldager, Ulla Mandel, Julie Van Coillie, Henrik Clausen, Eric P. Bennett, Lingbo Sun, Barbara A. Bensing, Catharina Steentoft, Ajit Varki, Yoshiki Narimatsu
Publikováno v:
Molecular Cell, 75, 394
Molecular cell, vol 75, iss 2
Molecular Cell
Mol Cell
Molecular Cell, 75, 2, pp. 394
Molecular cell, vol 75, iss 2
Molecular Cell
Mol Cell
Molecular Cell, 75, 2, pp. 394
The structural diversity of glycans on cells-the glycome-is vast and complex to decipher. Glycan arrays display oligosaccharides and are used to report glycan hapten binding epitopes. Glycan arrays are limited resources and present saccharides withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126238f55ccf7a4a957642def63743f4
http://hdl.handle.net/2066/206036
http://hdl.handle.net/2066/206036
Autor:
Federico Battisti, Hans Schreiber, Sergey Y. Vakhrushev, Yoshiki Narimatsu, Hiren J. Joshi, Catharina Steentoft, Ulla Mandel, Julie Van Coillie, Thomas Daugbjerg Madsen, Diana Campos, Adnan Halim, Max Fuhrmann
Publikováno v:
Glycobiology. 29(4)
Successful application of potent antibody-based T-cell engaging immunotherapeutic strategies is currently limited mainly to hematological cancers. One major reason is the lack of well-characterized antigens on solid tumors with sufficient cancer spec