Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Catharina Reker-Smit"'
Autor:
Adhyatmika Adhyatmika, Kurnia S. S. Putri, Emilia Gore, Keri A. Mangnus, Catharina Reker-Smit, Detlef Schuppan, Leonie Beljaars, Peter Olinga, Barbro N. Melgert
Publikováno v:
Cellular Physiology and Biochemistry, Vol 56, Iss 1, Pp 28-38 (2022)
Externí odkaz:
https://doaj.org/article/e12d0fc7887a48bd8a9d137e079c8f9c
Autor:
Christina Draijer, Laura Florez-Sampedro, Catharina Reker-Smit, Eduard Post, Fransien van Dijk, Barbro N. Melgert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionDifferentially polarized macrophages, especially YM1+ and MHCII+ macrophages, play an important role in asthma development. The origin of these polarized macrophages has not been elucidated yet. We therefore aimed to investigate how proli
Externí odkaz:
https://doaj.org/article/ae9cb35b0b4a4c2fb8af71dd99b4d8c3
Autor:
Adhyatmika Adhyatmika, Leonie Beljaars, Kurnia S. S. Putri, Habibie Habibie, Carian E. Boorsma, Catharina Reker-Smit, Theerut Luangmonkong, Burak Guney, Axel Haak, Keri A. Mangnus, Eduard Post, Klaas Poelstra, Kim Ravnskjaer, Peter Olinga, Barbro N. Melgert
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 471 (2020)
Osteoprotegerin (OPG) serum levels are associated with liver fibrogenesis and have been proposed as a biomarker for diagnosis. However, the source and role of OPG in liver fibrosis are unknown, as is the question of whether OPG expression responds to
Externí odkaz:
https://doaj.org/article/b319b910af32449c8e3333c092aedcec
Autor:
Marike Marjolijn van Beuge, Jai Prakash, Marie Lacombe, Eduard Post, Catharina Reker-Smit, Leonie Beljaars, Klaas Poelstra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56442 (2013)
Transforming growth factor-β (TGF-β) is a major pro-fibrotic cytokine, causing the overproduction of extracellular matrix molecules in many fibrotic diseases. Inhibition of its type-I receptor (ALK5) has been shown to effectively inhibit fibrosis i
Externí odkaz:
https://doaj.org/article/9869142f40a04ce494f7fc4c90a4e6b5
Autor:
Hamoon Hemmatpour, Vahid Haddadi-Asl, Thomas C. Q. Burgers, Feng Yan, Marc C. A. Stuart, Catharina Reker-Smit, Rifka Vlijm, Anna Salvati, Petra Rudolf
Publikováno v:
Nanoscale, 15, 2402-2416. ROYAL SOC CHEMISTRY
Administration of temperature-responsive drug carriers that release anticancer drugs at high temperatures can benefit hyperthermia therapies because of the synergistic effect of anticancer drug molecules and high temperature on killing the cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e45c89308c560bb31d5e77e06892b89
https://hdl.handle.net/11370/5c73ef32-bb54-4b7f-8ead-df40d8122699
https://hdl.handle.net/11370/5c73ef32-bb54-4b7f-8ead-df40d8122699
Publikováno v:
Acta Biomaterialia, 155, 507-520. ELSEVIER SCI LTD
Targeted drug delivery requires -among others- specific interaction of nanocarriers with cell surface receptors enabling efficient internalization into the targeted cells. Thus, identification of receptors allowing efficient nanocarrier uptake is ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8155efbffe01ddc987177557bf02fbe4
https://doi.org/10.1016/j.actbio.2022.11.010
https://doi.org/10.1016/j.actbio.2022.11.010
Autor:
Daphne Montizaan, Catherine Saunders, Keni Yang, Sajitha Sasidharan, Sourav Maity, Catharina Reker‐Smit, Marc C. A. Stuart, Costanza Montis, Debora Berti, Wouter H. Roos, Anna Salvati
Publikováno v:
Small.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcc86a641ebc31d81995bfe4f9b847a8
https://doi.org/10.1002/smll.202303267
https://doi.org/10.1002/smll.202303267
Autor:
Peter Olinga, Catharina Reker-Smit, Barbro N. Melgert, Kurnia Sari Setio Putri, Leonie Beljaars, Emilia Gore, Adhyatmika Adhyatmika, Keri A. Mangnus, Detlef Schuppan
1.AbstractBackgroundsOsteoprotegerin (OPG) is a profibrotic mediator produced by myofibroblasts under influence of transforming growth factor β (TGFβ). Its expression in experimental models of liver fibrosis correlates well with disease severity an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a6d39cba2b93578aabe15ab928bbe6e
https://doi.org/10.1101/2020.12.11.421479
https://doi.org/10.1101/2020.12.11.421479
Publikováno v:
Nanomedicine-Nanotechnology biology and medicine, 30:102300. ELSEVIER SCIENCE BV
Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine
Zwitterionic molecules are used as an alternative to PEGylation to reduce protein adsorption on nanocarriers. Nonetheless, little is known on the effect of zwitterionic modifications on the mechanisms cells use for nanocarrier uptake. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9117cec161813aac0c0f981bad9a2c9c
https://research.rug.nl/en/publications/2e7b4916-3463-4cb0-a160-c2f0f0864e08
https://research.rug.nl/en/publications/2e7b4916-3463-4cb0-a160-c2f0f0864e08
Autor:
Shardul A. Bhusari, Gwenda F Vasse, Qihui Zhou, Patrick van Rijn, Catharina Reker-Smit, Barbro N. Melgert, Philipp T. Kühn
Publikováno v:
Journal of Immunology and Regenerative Medicine, 1, 13-20
Fibrosis is a process in which an accumulation of extracellular matrix (ECM) leads to an impaired function of the affected organ. Pulmonary fibrosis is the end-stage of several lung diseases, characterized by scarring of the lungs. Although macrophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b35e25cf876fbd46eea3a61b66dd3f
https://hdl.handle.net/11370/8508ea9c-eb7c-44a0-b93c-f4a97764282c
https://hdl.handle.net/11370/8508ea9c-eb7c-44a0-b93c-f4a97764282c