Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Catharina R.E. Hilvering"'
Autor:
Vincent Wakker, Valerio Bianchi, Malou van den Boogaard, Wouter de Laat, Bastiaan J. Boukens, Vincent M. Christoffels, Rajiv A Mohan, Joyce C K Man, Catharina R.E. Hilvering, Catherine Jenkins, Phil Barnett
Publikováno v:
Nature communications, 10(1). Nature Publishing Group
Nature Communications, 10(1). Nature Publishing Group
Nature Communications, 10(1):4943. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, 10(1). Nature Publishing Group
Nature Communications, 10(1):4943. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Mutations and variations in and around SCN5A, encoding the major cardiac sodium channel, influence impulse conduction and are associated with a broad spectrum of arrhythmia disorders. Here, we identify an evolutionary conserved regulatory cluster wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99842cef87877259207f88955b62a24
https://doi.org/10.1038/s41467-019-12856-5
https://doi.org/10.1038/s41467-019-12856-5
Autor:
Carolina Roselli, James F. Martin, Valerio Bianchi, Nathan R. Tucker, Catharina R.E. Hilvering, Matthew C. Hill, Patrick T. Ellinor, Geert Geeven, Amelia W. Hall, Wouter de Laat, Kenneth B. Margulies
SummaryMost disease-associated variants identified by population based genetic studies are non-coding, which compromises finding causative genes and mechanisms. Presumably they interact through looping with nearby genes to modulate transcription. Hi-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79c64b4fb9facbdf07afb671826f22d
https://doi.org/10.1101/705715
https://doi.org/10.1101/705715
Publikováno v:
Methods, 170, 17-32. Elsevier Science
Methods. Academic Press
Methods. Academic Press
Chromosome conformation capture (3C) methods measure DNA contact frequencies based on nuclear proximity ligation, to uncover in vivo genomic folding patterns. 4C-seq is a derivative 3C method, designed to search the genome for sequences contacting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fd933fc5f2593abc9c8ecbd5dadbf3
https://pubmed.ncbi.nlm.nih.gov/31351925
https://pubmed.ncbi.nlm.nih.gov/31351925
Autor:
Jenna Bekeny, Christopher R. Weber, Margaret Gadek, Wouter de Laat, Xinan Yang, Valerio Bianchi, Joseph A. Goldman, Catharina R.E. Hilvering, Kenneth D. Poss, Stefan R Mazurek, Nutishia Lee, Rangarajan D. Nadadur, Alexander J. Ruthenburg, Ivan P. Moskowitz, Kaitlyn M Shen, Michael S. Werner, Leonid Tyan, Ozanna Burnicka-Turek, Carlos Perez-Cervantes, Johnathon M Hall
Publikováno v:
eLife, 6. eLife Sciences Publications
eLife
eLife, Vol 6 (2017)
Elife, 6:31683. eLife Sciences Publications, Ltd
eLife
eLife, Vol 6 (2017)
Elife, 6:31683. eLife Sciences Publications, Ltd
The noncoding genome is pervasively transcribed. Noncoding RNAs (ncRNAs) generated from enhancers have been proposed as a general facet of enhancer function and some have been shown to be required for enhancer activity. Here we examine the transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b255f6d02e9d468ef7b6226b31aa58
https://doi.org/10.7554/elife.31683
https://doi.org/10.7554/elife.31683
Autor:
Valerio Bianchi, Jenna Bekeny, Nutishia Lee, Xinan Yang, Alexander J. Ruthenburg, Rangarajan D. Nadadur, Ozanna Burnicka-Turek, Kenneth D. Poss, Stefan R Mazurek, Michael Werner, Wouter de Laat, Johnathon M Hall, Ivan P. Moskowitz, Catharina R.E. Hilvering, Joseph A. Goldman, Margaret Gadek, Leonid Tyan, Carlos Perez-Cervantes, Kaitlyn M Shen, Christopher R. Weber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7566c10069446538d080e7886e209296
https://doi.org/10.7554/elife.31683.021
https://doi.org/10.7554/elife.31683.021
Autor:
Carolina Roselli, Renate B. Schnabel, Valerio Bianchi, Aditi Trehan, Joseph E. Hadaya, Derek Klarin, Wouter de Laat, Amit Khera, Bradley E. Bernstein, Connor A. Emdin, Jesse M. Engreitz, Christian Mueller, Seyedeh M. Zekavat, Robbyn Issner, Russell J.H. Ryan, Catharina R.E. Hilvering, Noam Shoresh, Charles B. Epstein, Jonathan D. Brown, Sekar Kathiresan, Rajat M. Gupta
Publikováno v:
Cell, 170(3), 522-533.e15. Elsevier B.V.
Cell, 170(3), 522-533.e15. Cell Press
Cell, 170(3), 522. Cell Press
Cell, 170(3), 522-533.e15. Cell Press
Cell, 170(3), 522. Cell Press
Genome-wide association studies (GWASs) implicate the PHACTR1 locus (6p24) in risk for five vascular diseases, including coronary artery disease, migraine headache, cervical artery dissection, fibromuscular dysplasia, and hypertension. Through geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5854b1c98bf0052edf0cdd381a769d
https://pure.knaw.nl/portal/en/publications/722caf75-591a-4bc8-ac9b-67a211a4909a
https://pure.knaw.nl/portal/en/publications/722caf75-591a-4bc8-ac9b-67a211a4909a