Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Catharina C. Böhme"'
Publikováno v:
Journal of Biological Chemistry. 275:37317-37323
The homodimeric flavoenzyme glutathione reductase (GR) maintains high intracellular concentrations of the antioxidant glutathione (GSSG + NADPH + H+ ↔ 2 GSH + NADP+). Due to its central function in cellular redox metabolism, inhibition of GR from t
Autor:
Catharina C. Böhme, Michael Scheiwein, Gavin E. Arteel, Savvas N. Savvides, P. Andrew Karplus, R. Heiner Schirmer, Katja Becker
Publikováno v:
The Journal of biological chemistry. 277(4)
As part of our studies on the nitric oxide-related pathology of cerebral malaria, we show that the antioxidative enzyme glutathione reductase (GR) is inactivated by peroxynitrite, with GR from the malarial parasite Plasmodium falciparum being more se
Autor:
Katja Becker, Catharina C. Böhme, Stephan Gromer, Matthias Funk, R. Heiner Schirmer, Anke Fechner
Publikováno v:
Pediatric research. 49(2)
The pathophysiology of kwashiorkor, a severe edematous manifestation of malnutrition, is still poorly understood. The syndrome is, however, known to be associated with alterations in redox metabolism. To further elucidate the role of oxidative stress