Cells on Hydrogels with Micron-Scaled Stiffness Patterns Demonstrate Local Stiffness Sensing

Autor: Abbas Mgharbel, Camille Migdal, Nicolas Bouchonville, Paul Dupenloup, David Fuard, Eline Lopez-Soler, Caterina Tomba, Marie Courçon, Danielle Gulino-Debrac, Héléne Delanoë-Ayari, Alice Nicolas

Publikováno v: Nanomaterials, Vol 12, Iss 4, p 648 (2022)

Cell rigidity sensing—a basic cellular process allowing cells to adapt to mechanical cues—involves cell capabilities exerting force on the extracellular environment. In vivo, cells are exposed to multi-scaled heterogeneities in the mechanical pro

Externí odkaz: https://doaj.org/article/c7affd6f09b24affaa9af06a045a0fc1

Curvature in Biological Systems

Autor: Barbara Schamberger, Ricardo Ziege, Karine Anselme, Martine Ben Amar, Michał Bykowski, André P. G. Castro, Amaia Cipitria, Rhoslyn A. Coles, Rumiana Dimova, Michaela Eder, Sebastian Ehrig, Luis M. Escudero, Myfanwy E. Evans, Paulo R. Fernandes, Peter Fratzl, Liesbet Geris, Notburga Gierlinger, Edouard Hannezo, Aleš Iglič, Jacob J. K. Kirkensgaard, Philip Kollmannsberger, Łucja Kowalewska, Nicholas A. Kurniawan, Ioannis Papantoniou, Laurent Pieuchot, Tiago H. V. Pires, Lars D. Renner, Andrew O. Sageman‐Furnas, Gerd E. Schröder‐Turk, Anupam Sengupta, Vikas R. Sharma, Antonio Tagua, Caterina Tomba, Xavier Trepat, Sarah L. Waters, Edwina F. Yeo, Andreas Roschger, Cécile M. Bidan, John W. C. Dunlop

Publikováno v: Advanced Materials
Schamberger, B, Ziege, R, Anselme, K, Ben Amar, M, Bykowski, M, Castro, A P G, Cipitria, A, Coles, R A, Dimova, R, Eder, M, Ehrig, S, Escudero, L M, Evans, M E, Fernandes, P R, Fratzl, P, Geris, L, Gierlinger, N, Hannezo, E, Iglič, A, Kirkensgaard, J J K, Kollmannsberger, P, Kowalewska, Ł, Kurniawan, N A, Papantoniou, I, Pieuchot, L, Pires, T H V, Renner, L D, Sageman-Furnas, A O, Schröder-Turk, G E, Sengupta, A, Sharma, V R, Tagua, A, Tomba, C, Trepat, X, Waters, S L, Yeo, E F, Roschger, A, Bidan, C M & Dunlop, J W C 2023, ' Curvature in Biological Systems : Its Quantification, Emergence, and Implications across the Scales ', Advanced Materials, vol. 35, no. 13, 2206110 . https://doi.org/10.1002/adma.202206110

Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell membranes to single cells to tissues and organs. The relevance of surface curvature in biology is supported by numerous experimenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13fc88a450e0cd1e7ba7073cf40d1f2
http://www.scopus.com/inward/record.url?scp=85148379457&partnerID=8YFLogxK

Epithelial cells adapt to curvature induction via transient active osmotic swelling

Autor: Caterina Tomba, Valeriy Luchnikov, Luca Barberi, Carles Blanch-Mercader, Aurélien Roux

Publikováno v: Developmental Cell
Developmental Cell, 2022, 57, pp.1257-1270.e5. ⟨10.1016/j.devcel.2022.04.017⟩

International audience; Generation of tissue curvature is essential to morphogenesis. However, how cells adapt to changing curvatureis still unknown because tools to dynamically control curvature in vitro are lacking. Here, we developedself-rolling s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aa6854c95dd3b053d2d495dc5dc7e6
https://hal.science/hal-03678923

Transient active osmotic swelling of epithelium upon curvature induction

Autor: Luca Barberi, Aurélien Roux, Luchnikov, Caterina Tomba, Carles Blanch-Mercader

Generation of tissue curvature is essential to morphogenesis. However, how cells adapt to changing curvature is still unknown because tools to dynamically control curvature in vitro are lacking. Here we developed self-rolling substrates to study how

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e60b8926dbfc5a8c6934e6672f5daa7
https://hal.sorbonne-universite.fr/hal-03403492

Bending toward differentiation

Autor: Caterina, Tomba, Aurélien, Roux

Publikováno v: Developmental Cell. 56:3176-3177

Both biochemical and mechanical signals coordinate all processes at the origin of the formation of functional organs, including tissue folding, cell shape, and differentiation. In this issue of Developmental Cell, Blonski et al. establish a direct co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a1c9c1ba41a63f9ca12bd5cd07b00d
https://doi.org/10.1016/j.devcel.2021.11.013