Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Caterina Marchioretti"'
Autor:
Ramachandran Prakasam, Angela Bonadiman, Roberta Andreotti, Emanuela Zuccaro, Davide Dalfovo, Caterina Marchioretti, Debasmita Tripathy, Gianluca Petris, Eric N. Anderson, Alice Migazzi, Laura Tosatto, Anna Cereseto, Elena Battaglioli, Gianni Sorarù, Wooi Fang Lim, Carlo Rinaldi, Fabio Sambataro, Naemeh Pourshafie, Christopher Grunseich, Alessandro Romanel, Udai Bhan Pandey, Andrea Contestabile, Giuseppe Ronzitti, Manuela Basso, Maria Pennuto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Here, Prakasam and colleagues show that polyQ-expanded androgen receptor toxicity can be attenuated using artificial miRNAs targeting Lsd1 and Prmt6, two AR-co-activators overexpressed in an androgen-dependent manner specifically in skeletal muscle,
Externí odkaz:
https://doaj.org/article/9fd52a5a537f405caa90331491bb84a3
Autor:
Caterina Marchioretti, Giulia Zanetti, Marco Pirazzini, Gaia Gherardi, Leonardo Nogara, Roberta Andreotti, Paolo Martini, Lorenzo Marcucci, Marta Canato, Samir R. Nath, Emanuela Zuccaro, Mathilde Chivet, Cristina Mammucari, Marco Pacifici, Anna Raffaello, Rosario Rizzuto, Andrea Mattarei, Maria A. Desbats, Leonardo Salviati, Aram Megighian, Gianni Sorarù, Elena Pegoraro, Elisa Belluzzi, Assunta Pozzuoli, Carlo Biz, Pietro Ruggieri, Chiara Romualdi, Andrew P. Lieberman, Gopal J. Babu, Marco Sandri, Bert Blaauw, Manuela Basso, Maria Pennuto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Marchioretti and colleagues show that in the skeletal muscle of SBMA mice and patients there is an early, but reversible alteration of expression of genes involved in muscle contraction and of mitochondrial respiration, followed by accumulation of ca
Externí odkaz:
https://doaj.org/article/82a8527dca0543cd91761ed8387c3654
Autor:
Elisa Maria Turco, Angela Maria Giada Giovenale, Laura Sireno, Martina Mazzoni, Alessandra Cammareri, Caterina Marchioretti, Laura Goracci, Alessandra Di Veroli, Elena Marchesan, Daniel D’Andrea, Antonella Falconieri, Barbara Torres, Laura Bernardini, Maria Chiara Magnifico, Alessio Paone, Serena Rinaldo, Matteo Della Monica, Stefano D’Arrigo, Diana Postorivo, Anna Maria Nardone, Giuseppe Zampino, Roberta Onesimo, Chiara Leoni, Federico Caicci, Domenico Raimondo, Elena Binda, Laura Trobiani, Antonella De Jaco, Ada Maria Tata, Daniela Ferrari, Francesca Cutruzzolà, Gianluigi Mazzoccoli, Elena Ziviani, Maria Pennuto, Angelo Luigi Vescovi, Jessica Rosati
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-16 (2022)
Abstract Smith-Magenis syndrome (SMS) is a neurodevelopmental disorder characterized by cognitive and behavioral symptoms, obesity, and sleep disturbance, and no therapy has been developed to alleviate its symptoms or delay disease onset. SMS occurs
Externí odkaz:
https://doaj.org/article/3481a3d58ebf491c977d49d933ec8e59
Publikováno v:
Cells, Vol 12, Iss 3, p 502 (2023)
Skeletal muscle is the most abundant tissue in the body and requires high levels of energy to function properly. Skeletal muscle allows voluntary movement and body posture, which require different types of fiber, innervation, energy, and metabolism.
Externí odkaz:
https://doaj.org/article/d49f627a4a694818936830a0cee66d9b
Autor:
Samuel Valentini, Caterina Marchioretti, Alessandra Bisio, Annalisa Rossi, Sara Zaccara, Alessandro Romanel, Alberto Inga
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103531- (2021)
Summary: Few studies have explored the association between SNPs and alterations in mRNA translation potential. We developed an approach to identify SNPs that can mark allele-specific protein expression levels and could represent sources of inter-indi
Externí odkaz:
https://doaj.org/article/cd73ba21e26a4248a60c794741c3eafa
Autor:
Caterina Marchioretti, Emanuela Zuccaro, Udai Bhan Pandey, Jessica Rosati, Manuela Basso, Maria Pennuto
Publikováno v:
Cells, Vol 11, Iss 13, p 2105 (2022)
Polyglutamine diseases are characterized by selective dysfunction and degeneration of specific types of neurons in the central nervous system. In addition, nonneuronal cells can also be affected as a consequence of primary degeneration or due to neur
Externí odkaz:
https://doaj.org/article/cb251da92dcd44b58b067bfb22c14bbd
Autor:
Mathilde Chivet, Caterina Marchioretti, Marco Pirazzini, Diana Piol, Chiara Scaramuzzino, Maria Josè Polanco, Vanina Romanello, Emanuela Zuccaro, Sara Parodi, Maurizio D’Antonio, Carlo Rinaldi, Fabio Sambataro, Elena Pegoraro, Gianni Soraru, Udai Bhan Pandey, Marco Sandri, Manuela Basso, Maria Pennuto
Publikováno v:
Cells, Vol 9, Iss 2, p 325 (2020)
Polyglutamine (polyQ) expansions in the androgen receptor (AR) gene cause spinal and bulbar muscular atrophy (SBMA), a neuromuscular disease characterized by lower motor neuron (MN) loss and skeletal muscle atrophy, with an unknown mechanism. We gene
Externí odkaz:
https://doaj.org/article/7511012dd5ea4998bf29bae7fce0d28c
Autor:
Samir R. Nath, Diane M. Robins, Caterina Marchioretti, Maria Pennuto, Andrew P. Lieberman, Samuel T Jones, Kate M. Van Pelt, Zhigang Yu, Emily C E Danby, Gillian P. Bates, Matthew L Lieberman, Gianni Sorarù
Publikováno v:
Acta Neuropathologica. 140:63-80
Polyglutamine (polyQ) tract expansion leads to proteotoxic misfolding and drives a family of nine diseases. We study spinal and bulbar muscular atrophy (SBMA), a progressive degenerative disorder of the neuromuscular system caused by the polyQ androg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12793eb4a3a93f0054bbca8ce231f6f
https://doi.org/10.1007/s00401-020-02156-4
https://doi.org/10.1007/s00401-020-02156-4
Autor:
Caterina Marchioretti, Giulia Zanetti, Gaia Gherardi, Leonardo Nogara, Andreotti Roberta, Paolo Martini, Lorenzo Marcucci, Marta Canato, Samir Nath, Emanuela Zuccaro, Mathilde Chivet, Cristina Mammucari, Marco Pacifici, Anna Raffaello, Rosario Rizzuto, Andrea Mattarei, aram megighian, Gianni Sorarù, Elena Pegoraro, Elisa Belluzzi, Assunta Pozzuoli, Carlo Biz, Pietro Ruggieri, Chiara Romualdi, Andrew Lieberman, Gopal Babu, Marco Sandri, Bert Blaauw, Manuela Basso, Marco Pirazzini, Maria Pennuto
Polyglutamine (polyQ)-expanded androgen receptor (AR) causes spinobulbar muscular atrophy. Skeletal muscle is a primary site of polyQ-expanded AR toxicity, however it remains to be established what the early pathological processes are and how they un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e081c98d58bf8d2554d178e8ebc08f5
https://doi.org/10.21203/rs.3.rs-1261384/v1
https://doi.org/10.21203/rs.3.rs-1261384/v1
Autor:
Alberto Inga, Caterina Marchioretti, Alessandra Bisio, Alessandro Romanel, Samuel Valentini, Annalisa Rossi, Sara Zaccara
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103531-(2021)
iScience
iScience
Summary Few studies have explored the association between SNPs and alterations in mRNA translation potential. We developed an approach to identify SNPs that can mark allele-specific protein expression levels and could represent sources of inter-indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0a1451590554703d9351c8795627e3
http://www.sciencedirect.com/science/article/pii/S2589004221015029
http://www.sciencedirect.com/science/article/pii/S2589004221015029