Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Caterina Macrini"'
Autor:
Ramona Gerhards, Lena Kristina Pfeffer, Jessica Lorenz, Laura Starost, Luise Nowack, Franziska S. Thaler, Miriam Schlüter, Heike Rübsamen, Caterina Macrini, Stephan Winklmeier, Simone Mader, Mattias Bronge, Hans Grönlund, Regina Feederle, Hung-En Hsia, Stefan F. Lichtenthaler, Juliane Merl-Pham, Stefanie M. Hauck, Tanja Kuhlmann, Isabel J. Bauer, Eduardo Beltran, Lisa Ann Gerdes, Aleksandra Mezydlo, Amit Bar-Or, Brenda Banwell, Mohsen Khademi, Tomas Olsson, Reinhard Hohlfeld, Hans Lassmann, Tania Kümpfel, Naoto Kawakami, Edgar Meinl
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Autoimmune disorders of the central nervous system (CNS) comprise a broad spectrum of clinical entities. The stratification of patients based on the recognized autoantigen is of great importance for therapy optimization and for concepts of p
Externí odkaz:
https://doaj.org/article/48e9a477e7444c7f8deb69565051b888
Autor:
Iris Marti Fernandez, Caterina Macrini, Markus Krumbholz, Paul J. Hensbergen, Agnes L. Hipgrave Ederveen, Stephan Winklmeier, Atay Vural, Asli Kurne, Dieter Jenne, Frits Kamp, Lisa Ann Gerdes, Reinhard Hohlfeld, Manfred Wuhrer, Tania Kümpfel, Edgar Meinl
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoantibodies to myelin oligodendrocytes glycoprotein (MOG) are found in a fraction of patients with inflammatory demyelination and are detected with MOG-transfected cells. While the prototype anti-MOG mAb 8-18C5 and polyclonal anti-MOG responses fr
Externí odkaz:
https://doaj.org/article/0625c6d85031465797b02e7849f31245
Autor:
Simone Mader, Lena Bergmann, Michaela Smolle, Dieter E. Jenne, Stephan Winklmeier, Henri G. Franquelim, Edgar Meinl, Reinhard Hohlfeld, Caterina Macrini, Tania Kümpfel, Melania Spadaro, Atay Vural, Ramona Gerhards, Stefan F. Lichtenthaler
Publikováno v:
Brain
Brain 144(8), 2375-2389 (2021). doi:10.1093/brain/awab105
Brain 144(8), 2375-2389 (2021). doi:10.1093/brain/awab105
Antibodies to myelin oligodendrocyte glycoprotein (MOG-Abs) define a distinct disease entity. Here we aimed to understand essential structural features of MOG required for recognition by autoantibodies from patients. We produced the N-terminal part o
Autor:
Claudia Carvalho-Queiroz, Ola Nilsson, Andreas Kaiser, Guro Gafvelin, Stephan Winklmeier, Tomas Olsson, Mohsen Khademi, Edgar Meinl, Caterina Macrini, Sabrina Ruhrmann, Lou Brundin, Erik Holmgren, Mattias Bronge, Hans Grönlund
Publikováno v:
Journal of Autoimmunity. 102:38-49
Autoreactive CD4+ T-cells are believed to be a main driver of multiple sclerosis (MS). Myelin oligodendrocyte glycoprotein (MOG) is considered an autoantigen, yet doubted in recent years. The reason is in part due to low frequency and titers of MOG a
Autor:
Melania Spadaro, Klaus Dornmair, Stephan Winklmeier, Constanze Breithaupt, Markus Krumbholz, Markus Moser, Tania Kümpfel, Dieter E. Jenne, Franziska S. Thaler, Naoto Kawakami, Gurumoorthy Krishnamoorthy, Caterina Macrini, Ramona Gerhards, Frits Kamp, Romana Höftberger, Eduardo Beltrán, Simone M. Brändle, Elisabeth Schuh, Lisa Ann Gerdes, Reinhard Hohlfeld, Sarah Laurent, Hans Lassmann, Edgar Meinl
Publikováno v:
Annals of Neurology. 84:315-328
Objective Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with inflammatory demyelinating diseases of the central nervous system (CNS). We analyzed their pathogenic activity by affinity-purifying the
Autor:
Stephan Winklmeier, Atay Vural, Feyza Gül Özbay, Tania Kümpfel, Gunes Esendagli, Asli Kurne, Ramona Gerhards, Edgar Meinl, Miriam Schlüter, Simone Mader, Rana Karabudak, Franziska S. Thaler, Reinhard Hohlfeld, Berin Inan, Caterina Macrini, Melania Spadaro
Publikováno v:
Neurol Neuroimmunol Neuroinflamm
Neurology: Neuroimmunology and Neuroinflammation
Neurology® Neuroimmunology & Neuroinflammation
Neurology: Neuroimmunology and Neuroinflammation
Neurology® Neuroimmunology & Neuroinflammation
Objective: to identify circulating myelin oligodendrocyte glycoprotein (MOG)-specific B cells in the blood of patients with MOG antibodies (Abs) and to determine whether circulating MOG-specific B cells are linked to levels and epitope specificity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaecdde2f280d8d24e074f9e6964f6dc
https://europepmc.org/articles/PMC6935835/
https://europepmc.org/articles/PMC6935835/
Modeling compartmentalized chronic immune-mediated demyelinating CNS disease in the Biozzi ABH mouse
Autor:
Edgar Meinl, Siddharthan Chandran, Smadar Goldfarb, Yossi Nishri, David W. Hampton, Nina Fainstein, Caterina Macrini, Tamir Ben-Hur
Publikováno v:
Journal of Neuroimmunology. 356:577582
We explored whether experimental autoimmune encephalomyelitis (EAE) in Biozzi mice recapitulates temporal dynamics of tissue injury, immune-pathogenesis and CNS compartmentalization occurring in progressive multiple sclerosis (MS). Chronic EAE exhibi