Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caterina, Brindicci"'
Autor:
Marci Clark, Carla Romano, Oyebimpe Olayinka-Amao, Diane Whalley, Rebecca Crawford, Purnima Pathak, Caterina Brindicci, Kristin Garg, Kattayoun Kordy, Francois Everhard, Francesco Patalano, Zach Roesler, Thomas Sutton, Oskar Göransson, Ross Landles, Christel Naujoks, Jessica Marvel, Dorothy L. Keininger
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 6, Iss 1, Pp 1-13 (2022)
Abstract Background Childhood asthma is an important unmet need. To date, patient-reported outcome measures (PROMs) for children with asthma have used a combination of caregiver or proxy-reported and self-reported measures. No comprehensive measure i
Externí odkaz:
https://doaj.org/article/4972c1d510fb4c8eb127facd425312ea
Autor:
Björn Holzhauer, Lisa V. Hampson, John Paul Gosling, Björn Bornkamp, Joseph Kahn, Markus R. Lange, Wen‐Lin Luo, Caterina Brindicci, David Lawrence, Steffen Ballerstedt, Anthony O'Hagan
Publikováno v:
Pharmaceutical Statistics, 2022, Vol.21(5), pp.1005-1021 [Peer Reviewed Journal]
Pharmaceutical companies regularly need to make decisions about drug development programs based on the limited knowledge from early stage clinical trials. In this situation, eliciting the judgements of experts is an attractive approach for synthesisi
Autor:
Paul M, O'Byrne, Reynold A, Panettieri, Christian, Taube, Caterina, Brindicci, Margaret, Fleming, Pablo, Altman
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 78:102184
Thymic stromal lymphopoietin (TSLP), an epithelial cell-derived cytokine, acts as a key mediator in airway inflammation and modulates the function of multiple cell types, including dendritic cells and group 2 innate lymphoid cells. TSLP plays a role
Autor:
Thomas Lehmann, Samopriyo Maitra, Hiromasa Inoue, Jorge Maspero, Florian Brockhaus, Mina Gaga, Sally E. Wenzel, Jing Li, Barbara Knorr, Eugene R. Bleecker, Caterina Brindicci, David Lawrence, Christopher E. Brightling
Publikováno v:
The Lancet Respiratory Medicine. 9:43-56
Fevipiprant, an oral antagonist of the prostaglandin DLUSTER-1 and LUSTER-2 were two phase 3 randomised, double-blind, placebo-controlled, parallel-group, replicate 52-week studies; LUSTER-1 took place at 174 clinical sites in 25 countries and LUSTER
Autor:
Marci Clark, Carla Romano, Oyebimpe Olayinka-Amao, Diane Whalley, Rebecca Crawford, Purnima Pathak, Caterina Brindicci, Kristin Garg, Kattayoun Kordy, Francois Everhard, Francesco Patalano, Zach Roesler, Thomas Sutton, Oskar Göransson, Ross Landles, Christel Naujoks, Jessica Marvel, Dorothy L. Keininger
Publikováno v:
Journal of patient-reported outcomes. 6(1)
Background Childhood asthma is an important unmet need. To date, patient-reported outcome measures (PROMs) for children with asthma have used a combination of caregiver or proxy-reported and self-reported measures. No comprehensive measure is availab
Publikováno v:
Current Drug Targets
Background: Asthma and COPD are complex, heterogeneous conditions comprising a wide range of phenotypes, some of which are refractory to currently available treatments. Elucidation of these phenotypes and identification of biomarkers with which to re
Autor:
Rebecca Crawford, Marci Clark, Caterina Brindicci, Carla Romano, Francesco Patalano, Dorothy L. Keininger, Jessica Marvel, C. Naujoks, Thomas Sutton, Francois Everhard, Kristin Garg, Diane Whalley, Zach Roesler, Ross Landles, Oskar Goransson, Oyebimpe Olayinka-Amao, Kattayoun Kordy, Purnima Pathak
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:AB50
Autor:
James C. Hogg, Caterina Brindicci, Peter J. Barnes, Misako Ito, Sergei A. Kharitonov, Kazuhiro Ito, Mark W. Elliott
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 181:21-30
Nitric oxide (NO) is increased in the lung periphery of patients with chronic obstructive pulmonary disease (COPD). However, expression of the NO synthase(s) responsible for elevated NO has not been identified in the peripheral lung tissue of patient
Autor:
Caterina Brindicci, Toyoyuki Hanazawa, Grace O. Osoata, Misako Ito, Kazuhiro Ito, Peter J. Barnes, Sergei A. Kharitonov
Publikováno v:
Chest. 135:1513-1520
Peroxynitrite (PN) formed by the reaction of nitric oxide and superoxide is a powerful oxidant/nitrosant. Nitrative stress is implicated in COPD pathogenesis, but PN has not been detected due to a short half-life (1 s) at physiologic condition. Inste
Publikováno v:
Chest. 135:353-367
Background Nitric oxide (NO) is produced by resident and inflammatory cells in the respiratory tract by the enzyme NO synthase (NOS), which exists in three isoforms: neuronal NOS (nNOS), inducible NOS (iNOS), and endothelial NOS. NO production is inc