Peptide-Functionalized and Drug-Loaded Tomato Bushy Stunt Virus Nanoparticles Counteract Tumor Growth in a Mouse Model of Shh-Dependent Medulloblastoma

Autor: Luca Marchetti, Flavia Novelli, Barbara Tanno, Simona Leonardi, Veronica Mohamed Hizam, Caterina Arcangeli, Luca Santi, Selene Baschieri, Chiara Lico, Mariateresa Mancuso

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8911

Sonic hedgehog medulloblastoma (SHH-MB) accounts for 25–30% of all MBs, and conventional therapy results in severe long-term side effects. New targeted therapeutic approaches are urgently needed, drawing also on the fields of nanoparticles (NPs). A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6e4636f00d8cd522d335d5515ba7b1

Tomato Bushy Stunt Virus Nanoparticles as a Platform for Drug Delivery to Shh-Dependent Medulloblastoma

Autor: Barbara Tanno, Flavia Novelli, Roberta Bernini, Chiara Lico, Caterina Arcangeli, Simonetta Pazzaglia, Mariateresa Mancuso, Maurizio S. Podda, Luca Santi, Selene Baschieri, Luca Marchetti, Paola Giardullo

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10523, p 10523 (2021)

Background: Medulloblastoma (MB) is a primary central nervous system tumor that affects mainly young children. New strategies of drug delivery are urgent to treat this cancer and, in particular, the SHH-dependent subtype - the most common subgroup in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6852517b814d79f3bb66260bf68ba60

Dynamics at a Peptide-TiO

Autor: Marco, Polimeni, Loukas, Petridis, Jeremy C, Smith, Caterina, Arcangeli

Publikováno v: The journal of physical chemistry. B. 121(38)

The interface between biological matter and inorganic materials is a widely investigated research topic due to possible applications in biomedicine and nanotechnology. In this context, the molecular level adsorption mechanism that drives specific rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::546184bf29ff30bac2a07be901b2bc16
https://pubmed.ncbi.nlm.nih.gov/28851213

Variability and expression profile of the DRF1 gene in four cultivars of durum wheat and one triticale under moderate water stress conditions

Autor: Caterina Arcangeli, Cristina Cantale, Maria Sperandei, Arianna Latini, Patrizia Galeffi, Karim Ammar

Publikováno v: Planta. 237:967-978

The dehydration responsive element binding (DREB) proteins are important transcription factors that contribute to stress endurance in plants triggering the expression of a set of abiotic stress-related genes. A DREB2-related gene, previously referred

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c621f4c0623e04bc773869e5e9cd3f1d
https://doi.org/10.1007/s00425-012-1816-6

Adsorption of Modified Arg, Lys, Asp, and Gln to Dry and Hydrated ZnO Surface: A Density Functional Theory Study

Autor: Caterina Arcangeli, Francesco Buonocore, Massimo Celino, Fabrizio Gala, Giuseppe Zollo

Publikováno v: The journal of physical chemistry. B. 119(35)

The interface of biological molecules with inorganic surfaces has been the subject of several recent studies. Experimentally some amino acids are evidenced to play a critical role in the adhesion and selectivity on oxide surfaces; however, detailed i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f53d25d20eeb1eb83aa32b3a8ea30a5
https://pubmed.ncbi.nlm.nih.gov/26262824