Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Catelijne, Stortelers"'
Autor:
Carolina Pinto-Espinoza, Charlotte Guillou, Björn Rissiek, Maximilian Wilmes, Ehsan Javidi, Nicole Schwarz, Marten Junge, Friedrich Haag, Nastassia Liaukouskaya, Nicola Wanner, Annette Nicke, Catelijne Stortelers, Yossan-Var Tan, Sahil Adriouch, Tim Magnus, Friedrich Koch-Nolte
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The P2X7 ion channel is a key sensor for extracellular ATP and a key trigger of sterile inflammation. Intravenous injection of nanobodies that block P2X7 has shown to be beneficial in mouse models of systemic inflammation. P2X7 has also emerged as an
Externí odkaz:
https://doaj.org/article/386f3b67689741c29d0bc06c088e84e7
Autor:
Kerstin Schütze, Katharina Petry, Julia Hambach, Niklas Schuster, William Fumey, Levin Schriewer, Jana Röckendorf, Stephan Menzel, Birte Albrecht, Friedrich Haag, Catelijne Stortelers, Peter Bannas, Friedrich Koch-Nolte
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD38 is overexpressed by multiple myeloma cells and has emerged as a target for therapeutic antibodies. Nanobodies are soluble single domain antibody fragments derived from the VHH variable domain of heavy chain antibodies naturally occurring in came
Externí odkaz:
https://doaj.org/article/73386a564c9a465d8f987c717ce73431
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004902 (2016)
Post-exposure prophylaxis (PEP) against rabies infection consists of a combination of passive immunisation with plasma-derived human or equine immune globulins and active immunisation with vaccine delivered shortly after exposure. Since anti-rabies i
Externí odkaz:
https://doaj.org/article/7ba396b044814a5d947c2a5d44e5457d
Autor:
Iebe Rossey, Sandrine Vanmarcke, Sieglinde De Cae, Joana Rocha-Pereira, Xavier Saelens, Martin Schwemmle, Wander Van Breedam, Andrew Popplewell, Nick Devoogdt, Laurens Liesenborghs, Dominique Tersago, Annette Ohnemus, Kenny Roose, Simon Devos, Julius Beer, Piet Maes, Frank Peelman, Daniel Schnepf, Peter Staeheli, Sofie Jacobs, Wim Nerinckx, Massimiliano Germani, Catelijne Stortelers, George D. Moschonas, Kevin Brady, Alison Turner, Rana Abdelnabi, Daria Fijalkowska, Wannes Weyts, Isabel Remory, Leen Delang, Lana Langendries, Laura Seldeslachts, João Paulo Portela Catani, Bruno Dombrecht, Dries Van Herpe, Dirk Jochmans, Loes van Schie, Koen Sedeyn, Greetje Vande Velde, Chiara Lonigro, Sarah Creytens, Xin Zhang, Bert Schepens, Sebastiaan ter Horst, Kai Dallmeier, Hannah Eeckhaut, Caroline Shi-Yan Foo, Jimmy Borloo, Robbert Boudewijns, Suzanne J.F. Kaptein, James Heads, Nico Callewaert, Birgit Weynand, Mark Ellis, Ana Filipa Oliveira, Annelies Van Hecke, Gitte Michielsen, Dorien De Vlieger, Jackeline Cecilia Zavala Marchan, Alistair Henry, Johan Neyts, Hendrik Jan Thibaut
Publikováno v:
SCIENCE TRANSLATIONAL MEDICINE
Broadly neutralizing antibodies are an important treatment for individuals with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Antibody-based therapeutics are also essential for pandemic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3830e9b60d433a409a79548892804d43
https://lirias.kuleuven.be/handle/123456789/682263
https://lirias.kuleuven.be/handle/123456789/682263
Autor:
Sanne Terryn, Aurélie Francart, Sophie Lamoral, Anna Hultberg, Heidi Rommelaere, Angela Wittelsberger, Filip Callewaert, Thomas Stohr, Kris Meerschaert, Ingrid Ottevaere, Catelijne Stortelers, Peter Vanlandschoot, Michael Kalai, Steven Van Gucht
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109367 (2014)
Rabies virus causes lethal brain infection in about 61000 people per year. Each year, tens of thousands of people receive anti-rabies prophylaxis with plasma-derived immunoglobulins and vaccine soon after exposure. Anti-rabies immunoglobulins are how
Externí odkaz:
https://doaj.org/article/f73ce9c0c0a04bf6ab81b08828be58b4
Autor:
Piet Maes, Martin Schwemmle, Allison Turner, Annette Ohnemus, Wander Van Breedam, Greetje Vande Velde, Bert Schepens, Sieglinde De Cae, Suzanne J.F. Kaptein, Nick Devoogdt, James Heads, Mark Ellis, Peter Staeheli, Gitte Michielsen, Bruno Dombrecht, Julius Beer, Dominique Tersago, Robbert Boudewijns, Sofie Jacobs, Leen Delang, Dries Van Herpe, João Paulo Portela Catani, Dirk Jochmans, Alistair Henry, Rana Abdelnabi, Nico Callewaert, Birgit Weynand, Sandrine Vanmarcke, Sarah Creytens, Simon Devos, George D. Moschonas, Isabel Remory, Annelies Van Hecke, Lana Langendries, Daniel Schnepf, Catelijne Stortelers, Koen Sedeyn, Ana Filipa Oliveira, Laura Seldeslachts, Xin Zhang, Xavier Saelens, Loes van Schie, Laurens Liesenborghs, Dorien De Vlieger, Chiara Lonigro, Frank Peelman, Massimiliano Germano, Joana Rocha-Pereira, Kevin Brady, Wannes Weyts, Hendrik Jan Tibaut, Sebastiaan ter Horst, Kai Dallmeier, Hannah Eeckhaut, Jackeline Cecilia Zavala Marchan, Kenny Roose, Johan Neyts, Wim Nerinckx, Daria Fijalkowska, Andy Popplewell, Iebe Rossey, Caroline Shi-Yan Foo, Jimmy Borloo
We have identified camelid single-domain antibodies (VHHs) that cross-neutralize SARS-CoV-1 and −2, such as VHH72, which binds to a unique highly conserved epitope in the viral receptor-binding domain (RBD) that is difficult to access for human ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d213f47d21cc67cf73c8fd52a12112a4
https://doi.org/10.1101/2021.03.08.433449
https://doi.org/10.1101/2021.03.08.433449
Autor:
João R. Gomes, Renata Nogueira, Hugo R. Soares, Angela Wittelsberger, Sandra Macedo-Ribeiro, A. Teixeira, Catelijne Stortelers, Peter Vanlandschoot, Maria João Saraiva, Zsuzsa Sárkány, Inês Cabrito
Publikováno v:
ACS chemical neuroscience. 10(1)
Transthyretin (TTR) has intrinsic neurotrophic physiological activities independent from its thyroxine ligands, which involve activation of signaling pathways through interaction with megalin. Still, the megalin binding motif on TTR is unknown. Nanob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed37889310593c925810d6f34122958c
https://pubmed.ncbi.nlm.nih.gov/30346709
https://pubmed.ncbi.nlm.nih.gov/30346709
Publikováno v:
Current opinion in immunology. 52
Immune cells express various voltage-gated and ligand-gated ion channels that mediate the influx and efflux of charged ions across the plasma membrane, thereby controlling the membrane potential and mediating intracellular signal transduction pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be23d50343346c783e3128434a179df
https://pubmed.ncbi.nlm.nih.gov/29579624
https://pubmed.ncbi.nlm.nih.gov/29579624
Autor:
Angela Wittelsberger, João R. Gomes, A. Teixeira, Susete Costelha, Catelijne Stortelers, Hugo R. Soares, Peter Vanlandschoot, Maria João Saraiva, Inês Cabrito
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Transthyretin (TTR) is a transport protein of retinol and thyroxine in serum and CSF, which is mainly secreted by liver and choroid plexus, and in smaller amounts in other cells throughout the body. The exact role of TTR and its specific expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a9f2d0f2a70c41d628940f07cd8078
https://pubmed.ncbi.nlm.nih.gov/29527688
https://pubmed.ncbi.nlm.nih.gov/29527688
Autor:
William, Fumey, Julia, Koenigsdorf, Valentin, Kunick, Stephan, Menzel, Kerstin, Schütze, Mandy, Unger, Levin, Schriewer, Friedrich, Haag, Gerhard, Adam, Anna, Oberle, Mascha, Binder, Ralf, Fliegert, Andreas, Guse, Yong Juan, Zhao, Hon, Cheung Lee, Fabio, Malavasi, Fernando, Goldbaum, Rob, van Hegelsom, Catelijne, Stortelers, Peter, Bannas, Friedrich, Koch-Nolte
Publikováno v:
Scientific Reports
The cell surface ecto-enzyme CD38 is a promising target antigen for the treatment of hematological malignancies, as illustrated by the recent approval of daratumumab for the treatment of multiple myeloma. Our aim was to evaluate the potential of CD38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcb9f3bca31cf59f02019d43ed7cb558
https://pubmed.ncbi.nlm.nih.gov/29084989
https://pubmed.ncbi.nlm.nih.gov/29084989