Výsledky vyhledávání - "Catarina Osorio"

MicroRNA expression profiling in bone marrow: Implications in hematological malignancies

Autor: Ana Costa, Catarina Osorio, Sérgio Dias

Publikováno v: Biotechnology Journal. 4:88-97

MicroRNA (miRNA) have been recently attributed a crucial role in the control of gene expression in numerous physiological and pathological processes including growth, differentiation and even oncogenesis. Besides detailed mechanistic studies on their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b664bee5f046ebbc4ad7b280c51ca4c0
https://doi.org/10.1002/biot.200800194

Zobrazit plný text záznamu

TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment

Autor: Tânia Carvalho, Ana C. Santos, Catarina Osorio, Cátia Igreja, Sofia Correia, Manuela Ferreira, Ana Sofia Cachaço, Jacinta Serpa, Sergio Dias, Rita Fragoso, Perpétua Pinto-do-Ó

Publikováno v: PLoS ONE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS ONE, Vol 5, Iss 2, p e8980 (2010)

BACKGROUND Secondary bone marrow (BM) myelodysplastic syndromes (MDS) are increasingly common, as a result of radio or chemotherapy administered to a majority of cancer patients. Patients with secondary MDS have increased BM cell apoptosis, which res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e14ed40c64575afbb9d73aec0f6a69
https://hdl.handle.net/10362/21513

Zobrazit plný text záznamu

Susceptibility towards Irradiation-Induced Bone Marrow (BM) Dysplasia in Vivo Is Determined by the BM Vasculogenic Phenotype: Correlation with MDS Patients BM Samples

Autor: Catarina Osorio, Sergio Dias, Cátia Igreja, Andreia Mendonca, Tania Carvalho, Manuela Ferreira, Maria Gomes da Silva, Rita Fragoso

Publikováno v: Blood. 112:3638-3638

Bone marrow (BM) endothelial cells regulate hematopoiesis by promoting mobilization, survival and proliferation of hematopoietic progenitors. Interfering with BM endothelium function conditions BM recovery following myelosuppression. In the present s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d91d71e6e0e3345314c5763a751b7caa
https://doi.org/10.1182/blood.v112.11.3638.3638

Zobrazit plný text záznamu

A Mouse Strain Which Responds Poorly to Angiogenic Stimuli Has a Higher Incidence of Irradiation-Induced Hematological Malignancies

Autor: Sérgio Dias, Catia Igreja, Catarina Osorio, Rita Fragoso

Publikováno v: Blood. 110:4283-4283

Genetic heterogeneity of murine strains to vasculogenic/ angiogenic stimuli has been suggested to correlate with the susceptibility to carcinogenesis and subsequent tumor growth. A more “angiogenic” strain would, likely, be more prone to carcinog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d0b4a0b5143d7584389a7f3f36d5bc0
https://doi.org/10.1182/blood.v110.11.4283.4283

Zobrazit plný text záznamu