Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Catarina Oliveira, Miranda"'
Autor:
Catarina Oliveira Miranda, Rui Jorge Nobre, Vitor Hugo Paiva, João Valente Duarte, João Castelhano, Lorena Itatí Petrella, José Sereno, Magda Santana, Sónia Afonso, Cristina Januário, Miguel Castelo-Branco, Luís Pereira de Almeida
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Machado-Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is the most common form of dominant SCA worldwide. Magnetic Resonance Imaging (MRI) and Proton Magnetic Resonance Spectroscopy (1H-MRS) provide promising non-invasive diagn
Externí odkaz:
https://doaj.org/article/53fa6d99d59142e2a02374537d02c2c1
Autor:
Diana Duarte Lobo, Rui Jorge Nobre, Catarina Oliveira Miranda, Dina Pereira, João Castelhano, José Sereno, Arnulf Koeppen, Miguel Castelo-Branco, Luís Pereira de Almeida
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Blood-brain barrier (BBB) disruption is a common feature in neurodegenerative diseases. However, BBB integrity has not been assessed in spinocerebellar ataxias (SCAs) such as Machado-Joseph disease/SCA type 3 (MJD/SCA3), a genetic disorder,
Externí odkaz:
https://doaj.org/article/6ef536bc9a6442f3aa1022346306db58
Autor:
Carla Andreia Teixeira, Catarina Oliveira Miranda, Vera Filipe Sousa, Telma Emanuela Santos, Ana Rita Malheiro, Melani Solomon, Gustavo H. Maegawa, Pedro Brites, Mónica Mendes Sousa
Publikováno v:
Neurobiology of Disease, Vol 66, Iss , Pp 92-103 (2014)
In Krabbe's disease (KD), a leukodystrophy caused by β-galactosylceramidase deficiency, demyelination and a myelin-independent axonopathy contributes to the severe neuropathology. Beyond axonopathy, we show that in Twitcher mice, a model of KD, a de
Externí odkaz:
https://doaj.org/article/1e0c5975e49641b3b4dff45ec2c27d10
Mesenchymal stem cells for lysosomal storage and polyglutamine disorders: Possible shared mechanisms
Autor:
Catarina Oliveira Miranda
Publikováno v:
European journal of clinical investigationREFERENCES. 52(4)
BACKGROUND Mesenchymal stem cells' (MSC) therapeutic potential has been investigated for the treatment of several neurodegenerative diseases. The fact these cells can mediate a beneficial effect in different neurodegenerative contexts strengthens the
Autor:
Catarina Oliveira Miranda, Carla Andreia Teixeira, Vera Filipe Sousa, Telma Emanuela Santos, Márcia Almeida Liz, Ana Maio Marques, Perpétua Pinto-Do-Ó, Mónica Mendes Sousa
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Krabbe's disease (KD) is a demyelinating disorder caused by the deficiency of lysosomal galactocerebrosi-dase (GALC), affecting both the central (CNS) and the peripheral nervous system (PNS). A current therapy, hematopoietic stem cell transplantation
Externí odkaz:
https://doaj.org/article/f5735832d7c6419a9e624ce827b0cb44
Publikováno v:
Cytokine & Growth Factor Reviews
Highlights • SARS-CoV-2 can infect multiple organs leading to their dysfunction, so a pleiotropic therapy would be advantageous. • MSC: MSC can simultaneously address injuries in multiple organs and promote their repair. • MSC, immunomodulators
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Leukodystrophies are a group of disorders characterized by myelin dysfunction, either at the level of myelin formation or maintenance, that affect the central nervous system (CNS) and also in some cases, to a lesser extent, the peripheral nervous sys
Externí odkaz:
https://doaj.org/article/addfbe0ff0264b759152371e3598bc0b
Autor:
Joana Alves, José Sereno, Luís Pereira de Almeida, Lorena I. Petrella, Miguel Castelo-Branco, Isabel Nunes-Correia, Sónia Duarte, Catarina Oliveira Miranda, Adriana Marcelo, Dina Pereira, Paulo Rodrigues-Santos, Teresa Silva, Vitor H. Paiva, Clévio Nóbrega, Rui Jorge Nobre, Célia Gomes, João Castelhano, João Barata, Inês Barros, Vera Alves, Ana Vasconcelos-Ferreira
Publikováno v:
Molecular Therapy
Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3, the most common dominant spinocerebellar ataxia (SCA) worldwide, is caused by over-repetition of a CAG repeat in the ATXN3/MJD1 gene, which translates into a polyglutamine tract within th
Autor:
Rui Jorge Nobre, Catarina Oliveira Miranda, Diana Lobo, Dina Pereira, João Castelhano, Luís Pereira de Almeida, Miguel Castelo-Branco, José Sereno
Publikováno v:
Frontiers in Cellular Neuroscience. 13
Autor:
Sónia Duarte, Catarina Oliveira Miranda, Luís Pereira de Almeida, Beatriz Estremores, Albert R. La Spada, Janete Cunha-Santos, João Barata
Publikováno v:
Frontiers in Cellular Neuroscience. 13