Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Catarina Macedo-Silva"'
Autor:
Catarina Lopes, Tatiana C. Almeida, Catarina Macedo-Silva, João Costa, Sofia Paulino, Carmen Jerónimo, Diogo Libânio, Mário Dinis-Ribeiro, Carina Pereira
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Early gastric cancer is treated endoscopically, but patients require surveillance due to the risk of metachronous gastric lesions (MGLs). Epigenetic alterations, particularly aberrant DNA methylation in genes, such as MIR124-3, MI
Externí odkaz:
https://doaj.org/article/4a8ee649a4fd4451b5d9d8782129ef7e
Autor:
Ângela Albuquerque-Castro, Catarina Macedo-Silva, Rúben Oliveira-Sousa, Vera Constâncio, João Lobo, Isa Carneiro, Rui Henrique, Carmen Jerónimo
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract Accurate prostate cancer (PCa) patient diagnosis and risk assessment are key to ensure the best outcome. Currently, low- and favorable intermediate-risk PCa patients may be offered AS due to the indolent nature of the disease. Nonetheless, d
Externí odkaz:
https://doaj.org/article/2190867f8fc74d4a826c6a32a6d73af1
Autor:
Ângela Albuquerque-Castro, Catarina Macedo-Silva, Rúben Oliveira-Sousa, Vera Constâncio, João Lobo, Isa Carneiro, Rui Henrique, Carmen Jerónimo
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5118bcdd627e4d9cbd53cee4569d39c9
Autor:
Catarina Macedo-Silva, Vera Miranda-Gonçalves, Nuno Tiago Tavares, Daniela Barros-Silva, Joana Lencart, João Lobo, Ângelo Oliveira, Margareta P. Correia, Lucia Altucci, Carmen Jerónimo
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract External beam radiotherapy (RT) is a leading first-line therapy for prostate cancer (PCa), and, in recent years, significant advances have been accomplished. However, RT resistance can arise and result in long-term recurrence or disease prog
Externí odkaz:
https://doaj.org/article/65286e906b2b4ab4ae73151352e131b7
Autor:
Catarina Macedo‐Silva, Vera Constâncio, Vera Miranda‐Gonçalves, Pedro Leite‐Silva, Sofia Salta, João Lobo, Rita Guimarães, Carina Carvalho‐Maia, Davide Gigliano, Mónica Farinha, Olga Sousa, Rui Henrique, Carmen Jerónimo
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8777-8788 (2023)
Abstract Background Esophageal cancer (ECa) is associated with high mortality, mostly due to late diagnosis, precluding curativeintent surgery. Hence, neoadjuvant chemoradiation (ChRT) is recommended in most patients regardless of histological subtyp
Externí odkaz:
https://doaj.org/article/d970b954e26b4a219791784a6f9bb2cf
Autor:
Tânia Lima, Catarina Macedo-Silva, Diana Felizardo, João Fraga, Isa Carneiro, Carmen Jerónimo, Rui Henrique, Margarida Fardilha, Rui Vitorino
Publikováno v:
Current Oncology, Vol 30, Iss 3, Pp 2729-2742 (2023)
Gal-3 plays an important role in cell survival, mRNA splicing, and cell–cell and cell–matrix interactions. Depending on its cellular localization and cancer type, Gal-3 may have tumour-suppressive or tumour-promoting activities. Given the promisi
Externí odkaz:
https://doaj.org/article/46e39dbe6aa24a499db3c00905c2b4ea
Autor:
Catarina Macedo-Silva, Vera Miranda-Gonçalves, Ana Lameirinhas, Joana Lencart, Alexandre Pereira, João Lobo, Rita Guimarães, Ana Teresa Martins, Rui Henrique, Isabel Bravo, Carmen Jerónimo
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-16 (2020)
Abstract Esophageal squamous cell carcinoma (ESCC), the most frequent esophageal cancer (EC) subtype, entails dismal prognosis. Hypoxia, a common feature of advanced ESCC, is involved in resistance to radiotherapy (RT). RT response in hypoxia might b
Externí odkaz:
https://doaj.org/article/06465f6b25844cd4bdf4c7005122d6c0
Autor:
Vera Miranda-Gonçalves, Ana Lameirinhas, Catarina Macedo-Silva, João Lobo, Paula C. Dias, Verónica Ferreira, Rui Henrique, Carmen Jerónimo
Publikováno v:
Cells, Vol 9, Iss 4, p 1053 (2020)
Background: Renal cell carcinoma (RCC) displays a glycolytic phenotype (Warburg effect). Increased lactate production, impacting on tumor biology and microenvironment modulation, has been implicated in epigenetic mechanisms’ regulation, leading to
Externí odkaz:
https://doaj.org/article/0c81f089b75346fe9f1a1e5b0fc3296d
Autor:
Catarina Macedo‐Silva, Vera Constâncio, Vera Miranda‐Gonçalves, Pedro Leite‐Silva, Sofia Salta, João Lobo, Rita Guimarães, Carina Carvalho‐Maia, Davide Gigliano, Mónica Farinha, Olga Sousa, Rui Henrique, Carmen Jerónimo
Publikováno v:
Cancer Medicine. 12:8777-8788
Autor:
Ângela Carvalho, Catarina Guimarães-Teixeira, Vera Constâncio, Mariana Fernandes, Catarina Macedo-Silva, Rui Henrique, Fernando Jorge Monteiro, Carmen Jerónimo
Publikováno v:
Biomaterials Science. 10:3296-3308
Lung cancer (LC) is a major cause of mortality. Late diagnosis, associated with limitations in tissue biopsies for adequate tumor characterization contribute to limited survival of lung cancer patients. Liquid biopsies have been introduced to improve