Differential effects of the N-terminal helix of FGF8b on the activity of a small-molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution.

Autor: Mineev KS; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Hargittay B; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Jin J; BMLS and Institute for Cell Biology and Neuroscience, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Catapano C; Institute of Physical and Theoretical Chemistry, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Dietz MS; Institute of Physical and Theoretical Chemistry, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Segarra M; BMLS and Institute for Cell Biology and Neuroscience, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Harwardt MS; Institute of Physical and Theoretical Chemistry, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Richter C; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Jonker HRA; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Saxena K; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Sreeramulu S; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Heilemann M; Institute of Physical and Theoretical Chemistry, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Acker-Palmer A; BMLS and Institute for Cell Biology and Neuroscience, Johann Wolfgang Goethe University, Frankfurt/Main, Germany., Schwalbe H; Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe University, Frankfurt/Main, Germany.

Publikováno v: FEBS letters [FEBS Lett] 2024 Oct; Vol. 598 (20), pp. 2518-2532. Date of Electronic Publication: 2024 Jul 12.

Channelrhodopsin-2 Oligomerization in Cell Membrane Revealed by Photo-Activated Localization Microscopy.

Autor: Bestsennaia E; Institute of Biological Information Processing 1, IBI-1 (Molecular and Cellular Physiology), Forschungszentrum Jülich, 52428, Jülich, Germany., Maslov I; Dynamic Bioimaging Lab, Advanced Optical Microscopy Centre and the Biomedical Research Institute, Hasselt University, B3590, Diepenbeek, Belgium.; Laboratory for Photochemistry and Spectroscopy, Division for Molecular Imaging and Photonics, Department of Chemistry, KU Leuven, 3001, Leuven, Belgium., Balandin T; Institute of Biological Information Processing 7, IBI-7 (Structural Biochemistry), Forschungszentrum Jülich, 52428, Jülich, Germany., Alekseev A; Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany., Yudenko A; Department of Biomedical Sciences, University Medical Center Groningen, University of Groningen, 9713 AV, Groningen, The Netherlands., Abu Shamseye A; Institute of Biological Information Processing 1, IBI-1 (Molecular and Cellular Physiology), Forschungszentrum Jülich, 52428, Jülich, Germany.; Institute of Biological Information Processing 7, IBI-7 (Structural Biochemistry), Forschungszentrum Jülich, 52428, Jülich, Germany., Zabelskii D; Institute of Biological Information Processing 7, IBI-7 (Structural Biochemistry), Forschungszentrum Jülich, 52428, Jülich, Germany.; European XFEL, 22869, Schenefeld, Germany., Baumann A; Institute of Biological Information Processing 1, IBI-1 (Molecular and Cellular Physiology), Forschungszentrum Jülich, 52428, Jülich, Germany., Catapano C; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, 60438, Frankfurt, Germany., Karathanasis C; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, 60438, Frankfurt, Germany., Gordeliy V; Institute of Biological Information Processing 7, IBI-7 (Structural Biochemistry), Forschungszentrum Jülich, 52428, Jülich, Germany., Heilemann M; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, 60438, Frankfurt, Germany., Gensch T; Institute of Biological Information Processing 1, IBI-1 (Molecular and Cellular Physiology), Forschungszentrum Jülich, 52428, Jülich, Germany., Borshchevskiy V; Institute of Biological Information Processing 7, IBI-7 (Structural Biochemistry), Forschungszentrum Jülich, 52428, Jülich, Germany.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Mar 11; Vol. 63 (11), pp. e202307555. Date of Electronic Publication: 2024 Feb 02.

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Biased activation of the receptor tyrosine kinase HER2.

Autor: Catapano C; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, Max-Von-Laue-Str. 7, 60438, Frankfurt, Germany., Rahm JV; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, Max-Von-Laue-Str. 7, 60438, Frankfurt, Germany., Omer M; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark.; Center for Cellular Signal Patterns (CellPAT), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark., Teodori L; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark.; Center for Cellular Signal Patterns (CellPAT), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark., Kjems J; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark.; Center for Cellular Signal Patterns (CellPAT), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark., Dietz MS; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, Max-Von-Laue-Str. 7, 60438, Frankfurt, Germany., Heilemann M; Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, Max-Von-Laue-Str. 7, 60438, Frankfurt, Germany. heilemann@chemie.uni-frankfurt.de.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2023 May 20; Vol. 80 (6), pp. 158. Date of Electronic Publication: 2023 May 20.

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