Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Catalina M. Meyer"'
Autor:
Josef G, Heuer, Catalina M, Meyer, Hana E, Baker, Andrea, Geiser, Jonathan, Lucchesi, Daniel, Xu, Matthew, Hamang, Jennifer A, Martin, Charlie, Hu, Kenneth D, Roth, Kannan, Thirunavukkarasu, Jorge, Alsina-Fernandez, Yanfei L, Ma
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:287-298
Urocortin-1 (UCN1) is a member of the corticotropin releasing hormone (CRH) family of peptides that acts through CRH-receptor 1 (CRHR1) and CRH-receptor 2 (CRHR2). UCN1 can induce the adrenocorticotropin hormone and downstream glucocorticoids through
Autor:
Ruslan D. Novosiadly, Michael Kalos, Gerald E. Hall, David Surguladze, Gregory P. Donoho, Thompson N. Doman, Jason R. Manro, Frank C. Dorsey, Krishna Chodavarapu, Manisha Brahmachary, Bo Tan, Alexander Nikolayev, Kenneth D. Roth, Carmine Carpenito, Shuang Luo, Xiaodong Huang, Bonita D. Jones, Catalina M. Meyer, Yanxia Li, Andrew Capen, Darin Chin, Andreas Sonyi, Erik R. Rasmussen, Zhao Hai Lu, Nelusha Amaladas, Sandaruwan Geeganage, David A. Schaer
Supplementary Figure Legends & Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057a178b991babc2517ecf5b994d7838
https://doi.org/10.1158/1078-0432.22471418.v1
https://doi.org/10.1158/1078-0432.22471418.v1
Autor:
Ruslan D. Novosiadly, Michael Kalos, Gerald E. Hall, David Surguladze, Gregory P. Donoho, Thompson N. Doman, Jason R. Manro, Frank C. Dorsey, Krishna Chodavarapu, Manisha Brahmachary, Bo Tan, Alexander Nikolayev, Kenneth D. Roth, Carmine Carpenito, Shuang Luo, Xiaodong Huang, Bonita D. Jones, Catalina M. Meyer, Yanxia Li, Andrew Capen, Darin Chin, Andreas Sonyi, Erik R. Rasmussen, Zhao Hai Lu, Nelusha Amaladas, Sandaruwan Geeganage, David A. Schaer
Figure S1. Efficacy of pemetrexed in Lewis Lung carcinoma model and metabolomic analysis of MC38 tumor bearing mice treated with 50 mg/kg of pemetrexed Figure S2. T cell inflamed phenotype induced by pemetrexed is modestly reduced in tumors upon comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcf5c80af2bf8dacf087ab7a6132752
https://doi.org/10.1158/1078-0432.22471421
https://doi.org/10.1158/1078-0432.22471421
Autor:
Ruslan D. Novosiadly, Michael Kalos, Gerald E. Hall, David Surguladze, Gregory P. Donoho, Thompson N. Doman, Jason R. Manro, Frank C. Dorsey, Krishna Chodavarapu, Manisha Brahmachary, Bo Tan, Alexander Nikolayev, Kenneth D. Roth, Carmine Carpenito, Shuang Luo, Xiaodong Huang, Bonita D. Jones, Catalina M. Meyer, Yanxia Li, Andrew Capen, Darin Chin, Andreas Sonyi, Erik R. Rasmussen, Zhao Hai Lu, Nelusha Amaladas, Sandaruwan Geeganage, David A. Schaer
Purpose:Combination strategies leveraging chemotherapeutic agents and immunotherapy have held the promise as a method to improve benefit for patients with cancer. However, most chemotherapies have detrimental effects on immune homeostasis and differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55d83fcda2c247c186c9439427cc003
https://doi.org/10.1158/1078-0432.c.6527882.v1
https://doi.org/10.1158/1078-0432.c.6527882.v1
Autor:
Dyann M. Segvich, Jose M. Irimia, Vincent S. Tagliabracci, Anna A. DePaoli-Roach, Peter J. Roach, Catalina M. Meyer
Publikováno v:
Journal of Biological Chemistry. 290:22686-22698
Glycogen, the repository of glucose in many cell types, contains small amounts of covalent phosphate, of uncertain function and poorly understood metabolism. Loss-of-function mutations in the laforin gene cause the fatal neurodegenerative disorder, L
Autor:
Sneha Surendran, Anna A. DePaoli-Roach, Peter J. Roach, Catalina M. Meyer, Dyann M. Segvich, Núria Morral, Jose M. Irimia
Publikováno v:
The Journal of biological chemistry. 292(25)
Disruption of the Gys2 gene encoding the liver isoform of glycogen synthase generates a mouse strain (LGSKO) that almost completely lacks hepatic glycogen, has impaired glucose disposal, and is pre-disposed to entering the fasted state. This study in
Autor:
Yasmeen Rahimi, Peter J. Roach, Carolyn A. Worby, Catalina M. Meyer, Dyann M. Segvich, Matthew S. Gentry, Anna A. DePaoli-Roach
Publikováno v:
Human Molecular Genetics. 21:1604-1610
Lafora disease is a fatal, progressive myoclonus epilepsy caused in ∼90% of cases by mutations in the EPM2A or EPM2B genes. Characteristic of the disease is the formation of Lafora bodies, insoluble deposits containing abnormal glycogen-like materi
Autor:
Catalina M. Meyer, Jose Irimia-Dominguez, Dale S. Edgerton, Christopher J. Ramnanan, E. Patrick Donahue, Alan D. Cherrington, Noelia Rivera, Peter J. Roach, Margaret Lautz, Doss W. Neal, Ben Farmer
Publikováno v:
Diabetes
OBJECTIVE Insulin-mediated suppression of hepatic glucose production (HGP) is associated with sensitive intracellular signaling and molecular inhibition of gluconeogenic (GNG) enzyme mRNA expression. We determined, for the first time, the time course
Autor:
Vincent S. Tagliabracci, Dyann M. Segvich, Anna A. DePaoli-Roach, Peter J. Roach, Catalina M. Meyer, Jose M. Irimia
Publikováno v:
The Journal of biological chemistry. 285(33)
Approximately 90% of cases of Lafora disease, a fatal teenage-onset progressive myoclonus epilepsy, are caused by mutations in either the EPM2A or the EPM2B genes that encode, respectively, a glycogen phosphatase called laforin and an E3 ubiquitin li
Autor:
Stephen F. Previs, Owen P. McGuinness, Lanmin Zhai, Cheryl B. Bock, Peter J. Roach, Jose M. Irimia, Catalina M. Meyer, Anna A. DePaoli-Roach, Caron L. Peper
Publikováno v:
The Journal of biological chemistry. 285(17)
Conversion to glycogen is a major fate of ingested glucose in the body. A rate-limiting enzyme in the synthesis of glycogen is glycogen synthase encoded by two genes, GYS1, expressed in muscle and other tissues, and GYS2, primarily expressed in liver