Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Catalina De la Fuente"'
Autor:
Rilda León, Daniela A. Gutiérrez, Claudio Pinto, Cristian Morales, Catalina de la Fuente, Cristóbal Riquelme, Bastián I. Cortés, Adrián González-Martin, David Chamorro, Nelson Espinosa, Pablo Fuentealba, Gonzalo I. Cancino, Silvana Zanlungo, Andrés E. Dulcey, Juan J. Marugan, Alejandra Álvarez Rojas
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundGrowing evidence suggests that the non-receptor tyrosine kinase, c-Abl, plays a significant role in the pathogenesis of Alzheimer’s disease (AD). Here, we analyzed the effect of c-Abl on the cognitive performance decline of APPSwe/PSEN1Δ
Externí odkaz:
https://doaj.org/article/6accec4f1b6445c78136a93af6f6172c
Autor:
Tamara Marín, Andrés E. Dulcey, Fabián Campos, Catalina de la Fuente, Mariana Acuña, Juan Castro, Claudio Pinto, María José Yañez, Cristian Cortez, David W. McGrath, Pablo J. Sáez, Kirill Gorshkov, Wei Zheng, Noel Southall, Maria Carmo-Fonseca, Juan Marugán, Alejandra R. Alvarez, Silvana Zanlungo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Niemann-Pick type A (NPA) disease is a fatal lysosomal neurodegenerative disorder caused by the deficiency in acid sphingomyelinase (ASM) activity. NPA patients present severe and progressive neurodegeneration starting at an early age. Currently, the
Externí odkaz:
https://doaj.org/article/eb6e916b22f74d1d9c8a35fe82a6b24e
Autor:
Aliosha I. Figueroa-Valdés, Catalina de la Fuente, Yessia Hidalgo, Ana María Vega-Letter, Rafael Tapia-Limonchi, Maroun Khoury, Francisca Alcayaga-Miranda
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Cell therapy is witnessing a notable shift toward cell-free treatments based on paracrine factors, in particular, towards small extracellular vesicles (sEV), that mimic the functional effect of the parental cells. While numerous sEV-based application
Externí odkaz:
https://doaj.org/article/0e67b4a08f6745e999d5b9ccf4f11a14
Autor:
Daniela A. Gutierrez, Lina M. Vargas, América Chandia-Cristi, Catalina de la Fuente, Nancy Leal, Alejandra R. Alvarez
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Spine pathology has been implicated in the early onset of Alzheimer’s disease (AD), where Aβ-Oligomers (AβOs) cause synaptic dysfunction and loss. Previously, we described that pharmacological inhibition of c-Abl prevents AβOs-induced synaptic a
Externí odkaz:
https://doaj.org/article/0c9113b7e2de41ac96633008caaedfe1
Autor:
Tamara Marín, Andrés E. Dulcey, Fabián Campos, Catalina de la Fuente, Mariana Acuña, Juan Castro, Claudio Pinto, María José Yañez, Cristian Cortez, David W. McGrath, Pablo J. Sáez, Kirill Gorshkov, Wei Zheng, Noel Southall, Maria Carmo-Fonseca, Juan Marugán, Alejandra R. Alvarez, Silvana Zanlungo
Publikováno v:
Frontiers in cell and developmental biology. 10
Niemann-Pick type A (NPA) disease is a fatal lysosomal neurodegenerative disorder caused by the deficiency in acid sphingomyelinase (ASM) activity. NPA patients present severe and progressive neurodegeneration starting at an early age. Currently, the
Autor:
Maria-Isabel Yuseff, Alejandra R. Alvarez, Cristian Valls, Silvana Zanlungo, Catalina De la Fuente, Juan Esteban Oyarzún, Jonathan Lagos, Mary Carmen Vázquez
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1076-1087
Lysosomes are dynamic organelles, which can fuse with a variety of targets and undergo constant regeneration. They can move along microtubules in a retrograde and anterograde fashion by using motor proteins, kinesin and dynein, being main players in
Autor:
Alejandra R. Alvarez, Catalina De la Fuente, Daniela A Gutiérrez, Lina Vargas, Nancy Leal, America Chandia-Cristi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Spine pathology has been implicated in the early onset of Alzheimer’s disease (AD), where Aβ-Oligomers (AβOs) cause synaptic dysfunction and loss. Previously, we described that pharmacological inhibition of c-Abl prevents AβOs-induced synaptic a
Autor:
Alejandra R. Alvarez, Fabian Campos, Wei Zheng, Juan J. Marugan, Silvana Zanlungo, Kirill Gorshkov, Catalina De la Fuente, Juan Castro, Mariana Acuña, Tamara Marín, Maria Carmo-Fonseca, Cristian Cortez, Nancy Leal, Andrés E. Dulcey
Publikováno v:
Molecular Genetics and Metabolism. 129:S165