Zobrazeno 1 - 10 of 30 pro vyhledávání: '"Catalina D. Alba Soto"'
1
Akademický článek
IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole
Autor: Ágata C. Cevey, Federico N. Penas, Catalina D. Alba Soto, Gerardo A. Mirkin, Nora B. Goren
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Anti-parasitic treatment for Chagas disease mainly relies on benznidazole, which is virtually the only drug available in the market. Besides its anti-parasitic effects, benznidazole has anti-inflammatory properties. In this work we studied the mechan
Externí odkaz: https://doaj.org/article/5b549f72290a47658f292520769d03de
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2
Akademický článek
Cascade Ligand- and Structure-Based Virtual Screening to Identify New Trypanocidal Compounds Inhibiting Putrescine Uptake
Autor: Lucas N. Alberca, María L. Sbaraglini, Juan F. Morales, Roque Dietrich, María D. Ruiz, Agustina M. Pino Martínez, Cristian G. Miranda, Laura Fraccaroli, Catalina D. Alba Soto, Carolina Carrillo, Pablo H. Palestro, Alan Talevi
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Chagas disease is a neglected tropical disease endemic to Latin America, though migratory movements have recently spread it to other regions. Here, we have applied a cascade virtual screening campaign combining ligand- and structure-based methods. In
Externí odkaz: https://doaj.org/article/53331ab65c424a36b52dbd0b7bb8c123
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4
Absence of interleukin-10 reduces progression of shiga toxin-induced hemolytic uremic syndrome
Autor: María Florencia Todero, María Victoria Ramos, Catalina D. Alba-Soto, Gonzalo Ezequiel Pineda, Alan Mauro Bernal, Andrea Cecilia Bruballa, Marina S. Palermo, Elsa Zotta, Bárbara Rearte, Martín A. Isturiz, Romina Jimena Fernandez-Brando
Publikováno v: Clinical Science. 135:575-588
Hemolytic Uremic Syndrome (HUS), a disease triggered by Shiga toxin (Stx), is characterized by hemolytic anemia, thrombocytopenia and renal failure. The inflammatory response mediated by polymorphonuclear neutrophils (PMNs) and monocytes is essential
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2134cc8934a1ba7e3f50d59ade46c70d
https://doi.org/10.1042/cs20200468
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5
IL-10 participates in the expansion and functional activation of CD8+ T cells during acute infection with Trypanosoma cruzi
Autor: Catalina D. Alba Soto, Stella Maris González-Cappa, Estela I. Batalla, Agustina M. Pino-Martinez, Cristian Gabriel Miranda
Publikováno v: Journal of Leukocyte Biology. 105:163-175
IL-10 is a pleiotropic cytokine with immunoregulatory functions affecting various cell types. In a model of experimental infection with the protozoan Trypanosoma cruzi (T. cruzi), we found increased morbidity and lower parasite control in IL-10 defic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae74e85a51dff35ad8a38566430146b
https://doi.org/10.1002/jlb.3a0318-111rr
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6
Strongyloidiasis Outside Endemic Areas: Long-term Parasitological and Clinical Follow-up After Ivermectin Treatment
Autor: Catalina D. Alba Soto, Pablo M Bravo, Paula Ruybal, Marcelo Radisic, Carlota López, Silvia A. Repetto, Stella M. González Cappa, Estela I. Batalla, Mariela Sierra, Vanesa Fridman, Marikena G. Risso
Publikováno v: Clinical Infectious Diseases. 66:1558-1565
Background Strongyloides stercoralis affects 30-100 million people worldwide. The first-line therapy is ivermectin. Cure is defined as the absence of larvae by parasitological methods 1 year after treatment. To date, no longitudinal parasitological s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98925636623e4347e90a2815e25603eb
https://doi.org/10.1093/cid/cix1069
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7
A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors
Autor: María Laura Sbaraglini, Seppo Parkkila, María Daniela Ruiz, Andrea Angeli, Luciana Gavernet, Claudiu T. Supuran, Carolina Carrillo, Manuel A. Llanos, Maria Villalba, Catalina D. Alba Soto, Alan Talevi
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 21-30 (2020)
Trypanosoma cruzi carbonic anhydrase (TcCA) has recently emerged as an interesting target for the design of new compounds to treat Chagas disease. In this study we report the results of a structure-based virtual screening campaign to identify novel a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e00e9c6d695c64d69f231333b6bad4
https://www.tandfonline.com/doi/full/10.1080/14756366.2019.1677638
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8
IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole
Autor: Catalina D. Alba Soto, Ágata Carolina Cevey, Federico Nicolás Penas, Nora Goren, Gerardo A. Mirkin
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Anti-parasitic treatment for Chagas disease mainly relies on benznidazole, which is virtually the only drug available in the market. Besides its anti-parasitic effects, benznidazole has anti-inflammatory properties. In this work we studied the mechan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4609f45a2e5aa78a2e3ec896564276
https://www.frontiersin.org/article/10.3389/fimmu.2019.01267/full
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9
Trypanosoma cruzi Journey from the Insect Vector to the Host Cell
Autor: Catalina D. Alba Soto, Stella M. González Cappa
Publikováno v: Chagas Disease ISBN: 9783030000530
Trypanosoma cruzi, etiological agent of Chagas disease, has evolved a complex interaction with mammalian cells and insect vector’s intestine. During its journey between these environments, it is subject to stressful changes. To overcome them, paras
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0862631bdce4557006464616b172298
https://doi.org/10.1007/978-3-030-00054-7_2
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10
Comparison between PCR and larvae visualization methods for diagnosis of Strongyloides stercoralis out of endemic area: A proposed algorithm
Autor: Carolina Andrea Berini, Carlota López, Silvia A. Repetto, Catalina D. Alba Soto, María Elisa Solana, Stella M. González Cappa, Paula Ruybal
Publikováno v: Acta Tropica. 157:169-177
Underdiagnosis of chronic infection with the nematode Strongyloides stercoralis may lead to severe disease in the immunosuppressed. Thus, we have set-up a specific and highly sensitive molecular diagnosis in stool samples. Here, we compared the accur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4adbb1bc5b07549e3315cd7e4275cf3
https://doi.org/10.1016/j.actatropica.2016.02.004
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