Novel Dormancy Mechanism of Castration Resistance in Bone Metastatic Prostate Cancer Organoids

Autor: Sanghee Lee, Theresa R. Mendoza, Danielle N. Burner, Michelle T. Muldong, Christina C. N. Wu, Catalina Arreola-Villanueva, Abril Zuniga, Olga Greenburg, William Y. Zhu, Jamillah Murtadha, Evodie Koutouan, Naomi Pineda, Hao Pham, Sung-Gu Kang, Hyun Tae Kim, Gabriel Pineda, Kathleen M. Lennon, Nicholas A. Cacalano, Catriona H. M. Jamieson, Christopher J. Kane, Anna A. Kulidjian, Terry Gaasterland, Christina A. M. Jamieson

Publikováno v: International journal of molecular sciences, vol 23, iss 6
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3203

Advanced prostate cancer (PCa) patients with bone metastases are treated with androgen pathway directed therapy (APDT). However, this treatment invariably fails and the cancer becomes castration resistant. To elucidate resistance mechanisms and to pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0301f2de503082db94b81e32c832c474
https://pubmed.ncbi.nlm.nih.gov/35328625