Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Catalin Mihalcioiu"'
Autor:
Thai Hien Tu, Ami Grunbaum, François Santinon, Alexandra Kazanova, Nicholas Rozza, Richard Kremer, Catalin Mihalcioiu, Christopher E. Rudd
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract COVID-19, caused by SARS-CoV-2, can lead to a severe inflammatory disease characterized by significant lymphopenia. However, the underlying cause for the depletion of T-cells in COVID-19 patients remains incompletely understood. In this stud
Externí odkaz:
https://doaj.org/article/f893adaa54fc42cb8cdbad8e742eed76
Autor:
Adriana Aguilar-Mahecha, Najmeh Alirezaie, Josiane Lafleur, Eric Bareke, Ewa Przybytkowski, Cathy Lan, Luca Cavallone, Myriam Salem, Manuela Pelmus, Olga Aleynikova, Celia Greenwood, Amanda Lovato, Cristiano Ferrario, Jean-François Boileau, Catalin Mihalcioiu, Josée-Anne Roy, Elizabeth Marcus, Federico Discepola, Jacek Majewski, Mark Basik
Publikováno v:
Genes, Vol 15, Iss 1, p 27 (2023)
The response of triple-negative breast cancer (TNBC) patients to pre-operative (neoadjuvant chemotherapy) is a critical factor of their outcome. To determine the effects of chemotherapy on the tumor genome and to identify mutations associated with ch
Externí odkaz:
https://doaj.org/article/0e7d84274b4e487890fe81187e5fd46f
Autor:
Bertrand Routy, Corentin Richard, Myriam Benlaïfaoui, Simon Grandjean Lapierre, Nicholas Armstrong, Afnan Al-Saleh, Mélodie Boko, Maxime Jacq, Ian R. Watson, Catalin Mihalcioiu, Arielle Elkrief, Maryam Tidjani Alou, Meriem Messaoudene, Khoudia Diop
Publikováno v:
Microbiology Research, Vol 13, Iss 1, Pp 140-151 (2022)
Fecal microbiome culturomics of a cancer patient treated with immune checkpoint inhibitors led to the identification of a Gram-negative, rod-shaped, obligate anaerobic, non-motile, non-spore-forming bacterium, designated strain kh20T, which was phylo
Externí odkaz:
https://doaj.org/article/133edb383fa74cba9d0a45383600f760
Autor:
Marion Tonneau, Alexis Nolin-Lapalme, Suzanne Kazandjian, Edouard Auclin, Justin Panasci, Myriam Benlaifaoui, Mayra Ponce, Afnan Al-Saleh, Wiam Belkaid, Sabrine Naimi, Catalin Mihalcioiu, Ian Watson, Mickael Bouin, Wilson Miller, Marie Hudson, Matthew K. Wong, Rossanna C. Pezo, Simon Turcotte, Karl Bélanger, Rahima Jamal, Paul Oster, Dominique Velin, Corentin Richard, Meriem Messaoudene, Arielle Elkrief, Bertrand Routy
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The microbiome is now regarded as one of the hallmarks of cancer and several strategies to modify the gut microbiota to improve immune checkpoint inhibitor (ICI) activity are being evaluated in clinical trials. Preliminary data regarding the upper ga
Externí odkaz:
https://doaj.org/article/adb7b6925dfe48898a2dcd6d9e30f8ad
Autor:
Jiarong Li, Anne Camirand, Mahvash Zakikhani, Karine Sellin, Yubo Guo, XiaoRui Luan, Catalin Mihalcioiu, Richard Kremer
Publikováno v:
JBMR Plus, Vol 6, Iss 6, Pp n/a-n/a (2022)
ABSTRACT Parathyroid hormone‐related protein (PTHrP) plays a major role in skeletal metastasis but its action mechanism has not been fully defined. We previously demonstrated the crucial importance of PTHrP in promoting mammary tumor initiation, gr
Externí odkaz:
https://doaj.org/article/5cf902cda00546e6aa845001d4905da8
Autor:
Omid Hamid, Brendan Curti, Craig L Slingluff, Mohammed Milhem, Jose Lutzky, Suthee Rapisuwon, Brian Gastman, Takami Sato, Marcus O Butler, Robert Andtbacka, Eddy Hsueh, Robert Weber, John Glaspy, Sekwon Jang, Sajeve Thomas, Karl D Lewis, Leonel Hernandez-Aya, John Hyngstrom, Adam Berger, Edward Levine, Montaser F Shaheen, Vinay Gupta, Svetomir N Markovic, Tawnya Bowles, Joel Claveau, Prejesh Philips, Shernan G Holtan, William Schmidt, Juan Paramo, Arvinda Padmanabhan, Daniel Milton, Andrew Pecora, Suprith Badarinath, John Keech, Sujith Kalmadi, Pallavi Kumar, Anna Bar, J Thaddeus Beck, Jeffrey B Travers, Catalin Mihalcioiu, Peter Beitsch, Edward C McCarron, Deepti Behl, Brent Blumenstein, Joanna J Peterkin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/5160c99c6dc74e998f952d3b03d4f787
Autor:
Ali Mehdi, Mikhael Attias, Niaz Mahmood, Ani Arakelian, Catalin Mihalcioiu, Ciriaco A. Piccirillo, Moshe Szyf, Shafaat Ahmed Rabbani
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Immune checkpoint inhibitors (ICPi) targeting the PD-1/PD-L1 pathway have shown marked success in patients with advanced melanoma. However, 60–70% of patients fail to respond, warranting a therapeutic intervention that could increase response rates
Externí odkaz:
https://doaj.org/article/486e47e75404430eac9ff29cf14a5c3d
Autor:
Surabhi Parashar, David Cheishvili, Niaz Mahmood, Ani Arakelian, Imrana Tanvir, Haseeb Ahmed Khan, Richard Kremer, Catalin Mihalcioiu, Moshe Szyf, Shafaat A. Rabbani
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Immune surveillance acts as a defense mechanism in cancer, and its disruption is involved in cancer progression. DNA methylation reflects the phenotypic identity of cells and recent data suggested that DNA methylation profiles of
Externí odkaz:
https://doaj.org/article/04072641a1564a9793a9c8b976a62e1b
Autor:
Stephen K. Chia, Susan L. Ellard, Mihaela Mates, Stephen Welch, Catalin Mihalcioiu, Wilson H. Miller, Karen Gelmon, Caroline Lohrisch, Vikaash Kumar, Sara Taylor, Linda Hagerman, Rachel Goodwin, Tao Wang, Shingo Sakashita, Ming S. Tsao, Elizabeth Eisenhauer, Penelope Bradbury
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-8 (2017)
Abstract Background The mechanisms of resistance to anti-human epidermal growth factor receptor 2 (HER 2) therapies are unclear but may include the tyrosine-protein kinase Met (c-Met), vascular endothelial growth factor (VEGF) and AXL pathways. Foret
Externí odkaz:
https://doaj.org/article/339a000fc2ce4f629f2c9ae8021f9690
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The plasminogen activator (PA) system is an extracellular proteolytic enzyme system associated with various physiological and pathophysiological processes. A large body of evidence support that among the various components of the PA system, urokinase
Externí odkaz:
https://doaj.org/article/69a9f563c7cf44be99f9239ed7fde834