Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.

Autor: Acosta-Uribe J; Grupo de Neurociencias de Antioquia (GNA), Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara. Santa Barbara, USA., Piña Escudero SD; Global Brain Health Institute (GBHI), Department of Neurology, University of California San Francisco. San Francisco, USA.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA., Cochran JN; HudsonAlpha Institute for Biotechnology. Huntsville, USA., Taylor JW; HudsonAlpha Institute for Biotechnology. Huntsville, USA., Castruita PA; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA., Jonson C; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA.; DataTecnica LLC, Washington DC, USA.; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Barinaga EA; HudsonAlpha Institute for Biotechnology. Huntsville, USA., Roberts K; HudsonAlpha Institute for Biotechnology. Huntsville, USA., Levine AR; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara. Santa Barbara, USA., George DS; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara. Santa Barbara, USA., ÁvilaFunes JA; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Ciudad de México, México.; Bordeaux Population Health Research Center, University of Bordeaux. Bordeaux, France., Behrens MI; Departamento de Neurología y Psiquiatría, Clínica Alemana-Universidad del Desarrollo. Santiago, Chile.; Centro de Investigación Clínica Avanza (CICA), Departamento de Neurología y Neurocirugía and Departamento de Neurociencia, Facultad de Medicina, Universidad de Chile. Santiago, Chile., Bruno MA; Instituto de Ciencias Biomédicas (ICBM) Facultad de Ciencias Médicas, Universidad Católica de Cuyo. San Juan, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). San Juan, Argentina., Brusco LI; Asociación Alzheimer Argentina (ALZAR). Buenos Aires, Argentina.; Universidad de Buenos Aires. Buenos Aires, Argentina., Custodio N; Instituto Peruano de Neurociencias. Lima, Perú., Duran-Aniotz C; Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez. Santiago, Chile., Lopera F; Grupo de Neurociencias de Antioquia (GNA), Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia., Matallana DL; Instituto de Envejecimiento, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia.; Centro de Memoria y Cognición Intellectus, Hospital Universitario San Ignacio. Bogotá, Colombia.; Departamento de Salud Mental, Hospital Universitario Fundación Santa Fe. Bogotá, Colombia., Slachevsky A; Departamento de Neurología y Psiquiatría, Clínica Alemana-Universidad del Desarrollo. Santiago, Chile.; Laboratorio de Neuropsicología y Neurociencias Cognitivas (LANNEC) del Programa de Fisiopatología del Instituto de Ciencias Biomédicas (ICBM), Departamento de Ciencias Neurológicas Oriente y Departamento de Neurociencias de la Facultad de Medicina de la Universidad de Chile. Santiago, Chile.; Centro de Gerociencia, Salud Mental y Metabolismo (GERO). Santiago, Chile.; Centro de Memoria y Neuropsiquiatría (CMYN), Departamento de Neurología. Hospital del Salvador, Chile., Takada LT; Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo. São Paulo, Brasil., Zapata-Restrepo LM; Facultad de Ciencias de la Salud, Universidad Icesi. Cali, Colombia.; Fundación Valle de Lili. Cali, Colombia., Durón-Reyes DE; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Ciudad de México, México., de Paula França Resende E; Global Brain Health Institute (GBHI), Department of Neurology, University of California San Francisco. San Francisco, USA.; Faculdade de Medicina da Universidade Federal de Minas Gerais. Belo Horizonte, Brasil., Gelvez N; Instituto de genética humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia., Godoy ME; Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez. Santiago, Chile., Maito MA; Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez. Santiago, Chile., Javandel S; Global Brain Health Institute (GBHI), Department of Neurology, University of California San Francisco. San Francisco, USA.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA., Miller BL; Global Brain Health Institute (GBHI), Department of Neurology, University of California San Francisco. San Francisco, USA.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA., Nalls MA; DataTecnica LLC, Washington DC, USA.; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Leonard H; DataTecnica LLC, Washington DC, USA.; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Vitale D; DataTecnica LLC, Washington DC, USA.; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Bandres-Ciga S; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Koretsky MJ; DataTecnica LLC, Washington DC, USA.; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Singleton AB; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA.; National Institute on Aging, National Institutes of Health. Bethesda, USA., Pantazis CB; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health. Bethesda, USA., Valcour V; Global Brain Health Institute (GBHI), Department of Neurology, University of California San Francisco. San Francisco, USA.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA.; Division of Geriatric Medicine, University of California San Francisco. San Francisco, USA., Ibañez A; Latin American Institute for Brain Health (BrainLat), Universidad Adolfo Ibanez. Santiago, Chile.; Global Brain Health Institute, Trinity College Dublin. Dublin, Ireland., Kosik KS; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara. Santa Barbara, USA., Yokoyama JS; Global Brain Health Institute (GBHI), Department of Neurology, University of California San Francisco. San Francisco, USA.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco. San Francisco, USA.; Department of Radiology and Biomedical Imaging, University of California. San Francisco, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Nov 01. Date of Electronic Publication: 2024 Nov 01.

Genetic, Social, and Lifestyle Drivers of Healthy Aging and Longevity.

Autor: Castruita PA; Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.; Health Equity Research Lab, San Francisco State University, San Francisco, CA, USA., Piña-Escudero SD; Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.; Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA., Rentería ME; Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.; Mental Health & Neuroscience Program, QIMR Berghofer Medical Research Insitute, Brisbane, QLD, Australia., Yokoyama JS; Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.; Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.; Department of Neurology, Weill Institute of Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.

Publikováno v: Current genetic medicine reports [Curr Genet Med Rep] 2022 Sep; Vol. 10 (3), pp. 25-34. Date of Electronic Publication: 2022 Sep 26.

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).

Autor: Maor-Nof M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: maormaya@stanford.edu., Shipony Z; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Lopez-Gonzalez R; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Nakayama L; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Zhang YJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Couthouis J; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Blum JA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Castruita PA; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Linares GR; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA., Ruan K; Department of Neurology, Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD, USA., Ramaswami G; Department of Neurology, Program in Neurogenetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Simon DJ; Department of Biology, Stanford University, Stanford, CA, USA., Nof A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Santana M; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA., Han K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Sinnott-Armstrong N; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Geschwind DH; Department of Neurology, Program in Neurogenetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Tessier-Lavigne M; Department of Biology, Stanford University, Stanford, CA, USA., Attardi LD; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA., Lloyd TE; Department of Neurology, Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD, USA., Ichida JK; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA., Gao FB; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Greenleaf WJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Yokoyama JS; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: agitler@stanford.edu.

Publikováno v: Cell [Cell] 2021 Feb 04; Vol. 184 (3), pp. 689-708.e20. Date of Electronic Publication: 2021 Jan 21.