Výsledky vyhledávání - "Castro-Perez JM"

Akademický článek

Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5.

Autor: Zhang D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Tomisato W; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Su L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Sun L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Choi JH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Zhang Z; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Wang KW; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Choi M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Castro-Perez JM; Merck & Co., Inc., Kenilworth, NJ 07033., Hildebrand S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Murray AR; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Moresco EMY; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390-8505; bruce.beutler@UTSouthwestern.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Jun 27; Vol. 114 (26), pp. E5197-E5206. Date of Electronic Publication: 2017 Jun 12.

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Akademický článek

Duodenal-jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice.

Autor: Shang J; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Castro-Perez JM; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Shen X; Safety Assessment and Laboratory Animal Resource, Merck Research Laboratories, Kenilworth, New Jersey, USA., Zhu Y; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Liu H; Imaging, Merck Research Laboratories, Kenilworth, New Jersey, USA., Qian Y; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Previs S; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Howard AD; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Erion M; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Kelley DE; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA., Wang L; Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA.

Publikováno v: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2016 Sep; Vol. 24 (9), pp. 1938-45. Date of Electronic Publication: 2016 Jul 26.

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Akademický článek

Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux.

Autor: McLaren DG; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033 david_mclaren@merck.com., Previs SF; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Phair RD; Integrative Bioinformatics Inc., Mountain View, CA 94041., Stout SJ; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Xie D; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Chen Y; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Salituro GM; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Xu SS; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Castro-Perez JM; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Opiteck GJ; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Akinsanya KO; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Cleary MA; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Dansky HM; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Johns DG; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033., Roddy TP; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ 07033.

Publikováno v: Journal of lipid research [J Lipid Res] 2016 Mar; Vol. 57 (3), pp. 398-409. Date of Electronic Publication: 2015 Dec 09.

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Akademický článek

Quantitative profiling of oxylipins in plasma and atherosclerotic plaques of hypercholesterolemic rabbits.

Autor: Bojic LA; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA. lazar.bojic@merck.com., McLaren DG; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA., Harms AC; Leiden Amsterdam Centre for Drug Research, Netherlands Metabolomics Centre, 2300 LA, Leiden, The Netherlands., Hankemeier T; Leiden Amsterdam Centre for Drug Research, Netherlands Metabolomics Centre, 2300 LA, Leiden, The Netherlands., Dane A; Leiden Amsterdam Centre for Drug Research, Netherlands Metabolomics Centre, 2300 LA, Leiden, The Netherlands., Wang SP; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA., Rosa R; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA., Previs SF; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA., Johns DG; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA., Castro-Perez JM; Merck and Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, USA.

Publikováno v: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2016 Jan; Vol. 408 (1), pp. 97-105. Date of Electronic Publication: 2015 Oct 28.

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Akademický článek

Glucagon receptor antagonism induces increased cholesterol absorption.

Autor: Guan HP; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Yang X; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Lu K; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Wang SP; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Castro-Perez JM; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Previs S; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Wright M; Late Stage In Vitro Pharmacology, Merck Research Laboratories, Kenilworth, NJ 07033., Shah V; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Herath K; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Xie D; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Szeto D; Late Stage In Vivo Pharmacology, Merck Research Laboratories, Kenilworth, NJ 07033., Forrest G; Late Stage In Vivo Pharmacology, Merck Research Laboratories, Kenilworth, NJ 07033., Xiao JC; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Palyha O; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Sun LP; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Andryuk PJ; Clinical Research Department, Merck Research Laboratories, Rahway, NJ 07065., Engel SS; Clinical Research Department, Merck Research Laboratories, Rahway, NJ 07065., Xiong Y; Discovery Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033., Lin S; Discovery Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033., Kelley DE; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Erion MD; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Davis HR; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033., Wang L; Departments of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, NJ 07033.

Publikováno v: Journal of lipid research [J Lipid Res] 2015 Nov; Vol. 56 (11), pp. 2183-95. Date of Electronic Publication: 2015 Sep 15.

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Akademický článek

Lipidome of atherosclerotic plaques from hypercholesterolemic rabbits.

Autor: Bojic LA; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. lazar.bojic@merck.com., McLaren DG; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. david_mclaren@merck.com., Shah V; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. vinit_shah2@merck.com., Previs SF; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. stephen_previs@merck.com., Johns DG; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. douglas_johns@merck.com., Castro-Perez JM; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. jose_castro-perez@merck.com.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2014 Dec 15; Vol. 15 (12), pp. 23283-93. Date of Electronic Publication: 2014 Dec 15.

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Akademický článek

Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma.

Autor: Shah V; Analytical Biochemistry and Molecular Biomarkers, Merck Research Laboratories, Kenilworth, NJ 07033, USA. vinit_shah2@merck.com, Castro-Perez JM, McLaren DG, Herath KB, Previs SF, Roddy TP

Publikováno v: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2013 Oct 15; Vol. 27 (19), pp. 2195-200.

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Akademický článek

Use of [13C18] oleic acid and mass isotopomer distribution analysis to study synthesis of plasma triglycerides in vivo: analytical and experimental considerations.

Autor: McLaren DG; Merck Research Laboratories, Merck & Co., Inc., Kenilworth, New Jersey 07033, USA. David_McLaren@merck.com, Cardasis HL, Stout SJ, Wang SP, Mendoza V, Castro-Perez JM, Miller PL, Murphy BA, Cumiskey AM, Cleary MA, Johns DG, Previs SF, Roddy TP

Publikováno v: Analytical chemistry [Anal Chem] 2013 Jul 02; Vol. 85 (13), pp. 6287-94. Date of Electronic Publication: 2013 Jun 10.

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