Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

Autor: Navis, Anna C, van Lith, Sanne A M, van Duijnhoven, Sander M J, de Pooter, Maaike, Yetkin-Arik, Bahar, Wesseling, Pieter, Hendriks, Wiljan J A J, Venselaar, Hanka, Timmer, Marco, van Cleef, Patricia, van Bergen En Henegouwen, Paul, Best, Myron G, Wurdinger, Thomas D, Tops, Bastiaan B J, Leenders, William P J, Celbiologie, Sub Cell Biology

Publikováno v: Navis, A C, van Lith, S A M, van Duijnhoven, S M J, de Pooter, M, Yetkin-Arik, B, Wesseling, P, Hendriks, W J A J, Venselaar, H, Timmer, M, van Cleef, P, Henegouwen, P V E, Best, M G, Würdinger, T, Tops, B B J & Leenders, W P J 2015, ' Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein ', Acta Neuropathologica, vol. 130, no. 1, pp. 131-144 . https://doi.org/10.1007/s00401-015-1420-5
Acta Neuropathologica
Acta neuropathologica, 130(1), 131-44. Springer Verlag
Acta Neuropathologica, 130(1), 131-144. Springer Verlag
Acta Neuropathologica, 130(1), 131. Springer Verlag
Acta Neuropathologica, 130, 131-44
Acta Neuropathologica, 130, 1, pp. 131-44

Contains fulltext : 153045.pdf (Publisher’s version ) (Open Access) MET has gained interest as a therapeutic target for a number of malignancies because of its involvement in tumorigenesis, invasion and metastasis. At present, a number of inhibitor

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https://research.vumc.nl/en/publications/ad16c465-02c2-41ff-a56f-407d26a1dc3a