Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Castrén ML"'
Autor:
Juho Pitkonen, Asta Laiho, Noora Putkonen, Anna-Kaisa Anttonen, Adriana Gentile, Maija L. Castrén, Juha-Pekka Pursiheimo, Doug Ethell, Yolanda de Diego-Otero
Publikováno v:
Cells
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 289 (2020)
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 289 (2020)
A triplet repeat expansion leading to transcriptional silencing of the FMR1 gene results in fragile X syndrome (FXS), which is a common cause of inherited intellectual disability and autism. Phenotypic variation requires personalized treatment approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddcb0888607d9127feaea578c4c1411
Autor:
Talvio K; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Castrén ML; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Publikováno v:
Frontiers in cellular neuroscience [Front Cell Neurosci] 2024 Jan 08; Vol. 17, pp. 1322541. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2023).
An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis.
Autor:
Talvio K; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Wagner VA; Division of Biomedical Sciences, and Neuroscience Graduate Program, School of Medicine, University of California Riverside, Riverside, CA, USA., Minkeviciene R; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Kirkwood JS; Metabolomics Core Facility, Institute for Integrative Genome Biology, University of California Riverside, Riverside, CA, USA., Kulinich AO; Division of Biomedical Sciences, and Neuroscience Graduate Program, School of Medicine, University of California Riverside, Riverside, CA, USA., Umemori J; Gene and Cell Technology, A.I.Virtanen Institute, University of Eastern Finland, Kuopio, Finland., Bhatia A; Metabolomics Core Facility, Institute for Integrative Genome Biology, University of California Riverside, Riverside, CA, USA., Hur M; Metabolomics Core Facility, Institute for Integrative Genome Biology, University of California Riverside, Riverside, CA, USA., Käkelä R; Helsinki University Lipidomics Unit, HiLIPID, Helsinki Institute of Life Science, HiLIFE, Biocenter Finland (Metabolomics), and Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Ethell IM; Division of Biomedical Sciences, and Neuroscience Graduate Program, School of Medicine, University of California Riverside, Riverside, CA, USA., Castrén ML; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland. maija.castren@helsinki.fi.
Publikováno v:
Communications biology [Commun Biol] 2023 Jul 29; Vol. 6 (1), pp. 789. Date of Electronic Publication: 2023 Jul 29.
Autor:
Talvio K; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Minkeviciene R; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Townsley KG; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Achuta VS; Department of Neurology, Medical University of Vienna, Vienna, Austria., Huckins LM; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, United States., Corcoran P; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Brennand KJ; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, United States.; Department of Genetics, Yale University, New Haven, CT, United States., Castrén ML; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Publikováno v:
Frontiers in cell and developmental biology [Front Cell Dev Biol] 2022 Nov 21; Vol. 10, pp. 1034679. Date of Electronic Publication: 2022 Nov 21 (Print Publication: 2022).
Autor:
Peteri UK; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Pitkonen J; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., de Toma I; Systems Neurobiology Laboratory, Barcelona Institute of Science and Technology, Barcelona, Spain., Nieminen O; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Utami KH; Department of Physiology, National University of Singapore (NUS), Singapore, Singapore., Strandin TM; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Corcoran P; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Roybon L; iPSC Laboratory for CNS Disease Modeling, Department of Experimental Medical Science, BMC D10, and MultiPark and the Lund Stem Cell Center, Lund University, Lund, Sweden., Vaheri A; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Ethell I; Biomedical Sciences, University of California Riverside School of Medicine, Riverside, California, USA., Casarotto P; Neuroscience Center, University of Helsinki, Helsinki, Finland., Pouladi MA; Department of Physiology, National University of Singapore (NUS), Singapore, Singapore.; British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Castrén ML; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Publikováno v:
Glia [Glia] 2021 Dec; Vol. 69 (12), pp. 2947-2962. Date of Electronic Publication: 2021 Aug 24.
Autor:
Talvio K; Faculty of Medicine, Physiology, University of Helsinki, P.O. Box 63, 00290, Helsinki, Finland., Kanninen KM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., White AR; Department of Pathology, University of Melbourne, Melbourne, VIC, Australia.; Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Koistinaho J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.; Neuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland., Castrén ML; Faculty of Medicine, Physiology, University of Helsinki, P.O. Box 63, 00290, Helsinki, Finland. maija.castren@helsinki.fi.
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine [Biometals] 2021 Aug; Vol. 34 (4), pp. 947-954. Date of Electronic Publication: 2021 Jun 05.
Autor:
Peteri UK; Faculty of Medicine, Department of Physiology, University of Helsinki, P.O. Box 63, FI-00290 Helsinki, Finland., Pitkonen J; Faculty of Medicine, Department of Physiology, University of Helsinki, P.O. Box 63, FI-00290 Helsinki, Finland., Utami KH; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore., Paavola J; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, FI-00290 Helsinki, Finland., Roybon L; Stem Cell Laboratory for CNS Disease Modeling, Department of Experimental Medical Science, Lund University, SE-221 84 Lund, Sweden.; MultiPark and the Lund Stem Cell Center, Lund University, SE-221 84 Lund, Sweden., Pouladi MA; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore., Castrén ML; Faculty of Medicine, Department of Physiology, University of Helsinki, P.O. Box 63, FI-00290 Helsinki, Finland.
Publikováno v:
Brain sciences [Brain Sci] 2021 Feb 09; Vol. 11 (2). Date of Electronic Publication: 2021 Feb 09.
Autor:
Utami KH; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Skotte NH; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen N, Denmark., Colaço AR; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen N, Denmark., Yusof NABM; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Sim B; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Yeo XY; Singapore Bioimaging Consortium, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Bae HG; Singapore Bioimaging Consortium, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Garcia-Miralles M; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Radulescu CI; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore; UK Dementia Research Institute, Department of Brain Sciences, Imperial College London, London, United Kingdom., Chen Q; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Chaldaiopoulou G; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Liany H; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Nama S; Institute of Medical Biology, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Peteri UA; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Sampath P; Institute of Medical Biology, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore., Castrén ML; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Jung S; Singapore Bioimaging Consortium, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Mann M; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen N, Denmark., Pouladi MA; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A∗STAR), Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: map@pouladilab.org.
Publikováno v:
Biological psychiatry [Biol Psychiatry] 2020 Sep 15; Vol. 88 (6), pp. 500-511. Date of Electronic Publication: 2020 May 13.
Autor:
Utami KH; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore. utami@pouladilab.org., Yusof NABM; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore., Kwa JE; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore., Peteri UK; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Castrén ML; Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Pouladi MA; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore. map@pouladilab.org.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. map@pouladilab.org.
Publikováno v:
Molecular autism [Mol Autism] 2020 May 27; Vol. 11 (1), pp. 41. Date of Electronic Publication: 2020 May 27.
Autor:
Putkonen N; Faculty of Medicine, Physiology, University of Helsinki, FI-00014 Helsinki, Finland., Laiho A; Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Tykistökatu 6A, FI-20520 Turku, Finland., Ethell D; Leucadia Therapeutics Inc., Riverside, CA 92506, USA., Pursiheimo J; The Joint Clinical Biochemistry Laboratory of University of Turku, University Central Hospital and Wallac Oy, FI-20520 Turku, Finland., Anttonen AK; Department of Clinical Genetics, University Hospital of Helsinki, 160, FI-00290 Helsinki, Finland., Pitkonen J; Faculty of Medicine, Physiology, University of Helsinki, FI-00014 Helsinki, Finland., Gentile AM; Institute of Biomedical Research of Malaga (IBIMA) and Mental Health Unit, Regional University Hospital of Malaga, University of Malaga, Research lab. Hospital Civil, Pab-6 sot. 29009 Malaga, Spain., de Diego-Otero Y; Institute of Biomedical Research of Malaga (IBIMA) and Mental Health Unit, Regional University Hospital of Malaga, University of Malaga, Research lab. Hospital Civil, Pab-6 sot. 29009 Malaga, Spain., Castrén ML; Faculty of Medicine, Physiology, University of Helsinki, FI-00014 Helsinki, Finland.; Rinnekoti Foundation, FIN-02980 Espoo, Finland.; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA 92521, USA.
Publikováno v:
Cells [Cells] 2020 Jan 24; Vol. 9 (2). Date of Electronic Publication: 2020 Jan 24.