Výsledky vyhledávání - "Castle John C"

Akademický článek

rapmad: Robust analysis of peptide microarray data

Autor: Rothermel Andrée, Reimer Ulf, Kühne Yvonne, Löwer Martin, Renard Bernhard Y, Türeci Özlem, Castle John C, Sahin Ugur

Publikováno v: BMC Bioinformatics, Vol 12, Iss 1, p 324 (2011)

Abstract Background Peptide microarrays offer an enormous potential as a screening tool for peptidomics experiments and have recently seen an increased field of application ranging from immunological studies to systems biology. By allowing the parall

Externí odkaz: https://doaj.org/article/d94523cb980b438f9b771c9203b53c51

Zobrazit plný text záznamu

Akademický článek

DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing

Autor: Jackson Stuart, Misura Kira, Chen Ronghua, Xie Tao, Bouzek Heather, Biery Matthew, Castle John C, Armour Christopher D, Johnson Jason M, Rohl Carol A, Raymond Christopher K

Publikováno v: BMC Genomics, Vol 11, Iss 1, p 244 (2010)

Abstract Background DNA copy number variations occur within populations and aberrations can cause disease. We sought to develop an improved lab-automatable, cost-efficient, accurate platform to profile DNA copy number. Results We developed a sequenci

Externí odkaz: https://doaj.org/article/9e4b29f8e3424d4db8a65fd111f31b4c

Zobrazit plný text záznamu

Akademický článek

Definition, conservation and epigenetics of housekeeping and tissue-enriched genes

Autor: Johnson Jason M, Kulkarni Amit V, Castle John C, Rohl Carol A, She Xinwei, Chen Ronghua

Publikováno v: BMC Genomics, Vol 10, Iss 1, p 269 (2009)

Abstract Background Housekeeping genes (HKG) are constitutively expressed in all tissues while tissue-enriched genes (TEG) are expressed at a much higher level in a single tissue type than in others. HKGs serve as valuable experimental controls in ge

Externí odkaz: https://doaj.org/article/41d691cb521d4484896596d626db78b7

Zobrazit plný text záznamu

Akademický článek

Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences

Autor: Schadt Eric E, Russell Archie, Kulkarni Amit V, Shah Jyoti K, Edwards Stephen, GuhaThakurta Debraj, Modrek Barmak, Su Wan-Lin, Johnson Jason M, Castle John C

Publikováno v: BMC Genomics, Vol 9, Iss 1, p 273 (2008)

Abstract Background Studies have shown that genetic and sex differences strongly influence gene expression in mice. Given the diversity and complexity of transcripts produced by alternative splicing, we sought to use microarrays to establish the exte

Externí odkaz: https://doaj.org/article/5e243641d1db4817a864071b003956b5

Zobrazit plný text záznamu