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pro vyhledávání: '"Cast, Oliver"'
Autor:
Kehrloesser, Sebastian, Cast, Oliver, Elliott, Thomas S, Ernst, Russell J, Machel, Anne C, Chen, Jia-Xuan, Chin, Jason W, Miller, Martin L
The ability to assign cellular origin to low-abundance secreted factors in extracellular vesicles (EVs) would greatly facilitate the analysis of paracrine-mediated signaling. Here, we report a method, named selective isolation of extracellular vesicl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::26fa674a159363e16b25f89c2ba0d7cc
https://www.repository.cam.ac.uk/handle/1810/349384
https://www.repository.cam.ac.uk/handle/1810/349384
Akademický článek
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Akademický článek
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Autor:
Jiménez-Sánchez, Alejandro, Cybulska, Paulina, Mager, Katherine LaVigne, Koplev, Simon, Cast, Oliver, Couturier, Dominique-Laurent, Memon, Danish, Selenica, Pier, Nikolovski, Ines, Mazaheri, Yousef, Bykov, Yonina, Geyer, Felipe C, Macintyre, Geoff, Gavarró, Lena Morrill, Drews, Ruben M, Gill, Michael B, Papanastasiou, Anastasios D, Sosa, Ramon E, Soslow, Robert A, Walther, Tyler, Shen, Ronglai, Chi, Dennis S, Park, Kay J, Hollmann, Travis, Reis-Filho, Jorge S, Markowetz, Florian, Beltrao, Pedro, Vargas, Hebert Alberto, Zamarin, Dmitriy, Brenton, James D, Snyder, Alexandra, Weigelt, Britta, Sala, Evis, Miller, Martin L
In metastatic cancer, the degree of heterogeneity of the tumor microenvironment (TME) and its molecular underpinnings remain largely unstudied. To characterize the tumor-immune interface at baseline and during neoadjuvant chemotherapy (NACT) in high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a911d35595afd10f063ffb03b6a92fc
Autor:
Luiza Moore, David J. Adams, Alejandro Jiménez-Sánchez, Mark Tullett, Laura Riva, Kim Wong, David C. Wedge, Martin L. Miller, Sarah J. Welsh, Doreen Lau, Christine Parkinson, Julia M. Martínez Gómez, Kieren Allinson, Pippa Corrie, Ingrid Ferreira, Francis Scott, Leila Khoja, Roy Rabbie, Naser Ansari-Pour, Peter J. Campbell, Mitchell P. Levesque, Ferdia A. Gallagher, Oliver Cast
Publikováno v:
Nature communications, 11 (1
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Rabbie, R, Ansari-pour, N, Cast, O, Lau, D, Scott, F, Welsh, S J, Parkinson, C, Khoja, L, Moore, L, Tullett, M, Wong, K, Ferreira, I, Gómez, J M M, Levesque, M, Gallagher, F A, Jiménez-sánchez, A, Riva, L, Miller, M L, Allinson, K, Campbell, P J, Corrie, P, Wedge, D C & Adams, D J 2020, ' Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-18060-0
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Rabbie, R, Ansari-pour, N, Cast, O, Lau, D, Scott, F, Welsh, S J, Parkinson, C, Khoja, L, Moore, L, Tullett, M, Wong, K, Ferreira, I, Gómez, J M M, Levesque, M, Gallagher, F A, Jiménez-sánchez, A, Riva, L, Miller, M L, Allinson, K, Campbell, P J, Corrie, P, Wedge, D C & Adams, D J 2020, ' Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-18060-0
Metastatic melanoma carries a poor prognosis despite modern systemic therapies. Understanding the evolution of the disease could help inform patient management. Through whole-genome sequencing of 13 melanoma metastases sampled at autopsy from a treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095bdd688d2e81502047a9bcbc7554f0
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/312055
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/312055
Autor:
Kehrloesser S; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Cast O; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Elliott TS; Medical Research Council Laboratory of Molecular Biology, Francis Crick Ave, Cambridge CB2 0QH, UK., Ernst RJ; Medical Research Council Laboratory of Molecular Biology, Francis Crick Ave, Cambridge CB2 0QH, UK., Machel AC; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Chen JX; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; Institute of Molecular Biology, Ackermannweg 4, 55128 Mainz, Germany., Chin JW; Medical Research Council Laboratory of Molecular Biology, Francis Crick Ave, Cambridge CB2 0QH, UK., Miller ML; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; Oncology Data Science, Oncology R&D, AstraZeneca, 1 Francis Crick Ave, Cambridge CB2 0AA, UK.
Publikováno v:
PNAS nexus [PNAS Nexus] 2023 Apr 03; Vol. 2 (4), pp. pgad107. Date of Electronic Publication: 2023 Apr 03 (Print Publication: 2023).