Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cassy Spiller"'
Publikováno v:
Stem Cell Research, Vol 24, Iss C, Pp 174-180 (2017)
There is now substantial evidence that members of the transforming growth factor-β (TGFβ family) regulate germ cell development in the mouse fetal testis. Correct development of germ cells during fetal life is critical for establishment of effectiv
Externí odkaz:
https://doaj.org/article/b0a01395a2524b46b9bc43daf464ce8f
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Recent findings have challenged the established concept that retinoic acid (RA) induces foetal germ cells to enter meiosis. Here, Bowles et al. identify the enzyme ALDH1A1 as a source of ovarian RA that may induce meiosis even when other RA-synthetic
Externí odkaz:
https://doaj.org/article/0e22b65b446446819a8346023e0c02d8
Autor:
Huijun Chen, James S Palmer, Rathi D Thiagarajan, Marcel E Dinger, Emmanuelle Lesieur, Hansheng Chiu, Alexandra Schulz, Cassy Spiller, Sean M Grimmond, Melissa H Little, Peter Koopman, Dagmar Wilhelm
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41683 (2012)
In contrast to the developing testis, molecular pathways driving fetal ovarian development have been difficult to characterise. To date no single master regulator of ovarian development has been identified that would be considered the female equivale
Externí odkaz:
https://doaj.org/article/9a55bde2d5c74b008558a269804d8743
Autor:
Raul Ayala Davila, Cassy Spiller, Danyon Harkins, Tracey Harvey, Philip W Jordan, Richard M Gronostajski, Michael Piper, Josephine Bowles
Publikováno v:
Biology of Reproduction. 106:1191-1205
Members of the nuclear factor I (NFI) family are key regulators of stem cell biology during development, with well-documented roles for NFIA, NFIB, and NFIX in a variety of developing tissues, including brain, muscle, and lung. Given the central role
Autor:
Cassy Spiller, Josephine Bowles
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation.
Background: Germ cells are critical for the survival of our species. They are the only cells that undergo meiosis – the reductive form of cell division that is necessary for genetic reassortment of chromosomes and production of the haploid gametes,
Autor:
Cassy Spiller
During development, somatic cell cues direct sex-specific differentiation of germ cells that is characterised by two distinct cell cycle states. At 12.5 days post coitum (dpc) in a testis, XY germ cells stop proliferating and enter G1/G0 arrest. In t
Externí odkaz:
http://espace.library.uq.edu.au/view/UQ:180111
Autor:
Cassy Spiller
During development, somatic cell cues direct sex-specific differentiation of germ cells that is characterised by two distinct cell cycle states. At 12.5 days post coitum (dpc) in a testis, XY germ cells stop proliferating and enter G1/G0 arrest. In t
Externí odkaz:
http://espace.library.uq.edu.au/view/UQ:180111
Autor:
Cassy Spiller
During development, somatic cell cues direct sex-specific differentiation of germ cells that is characterised by two distinct cell cycle states. At 12.5 days post coitum (dpc) in a testis, XY germ cells stop proliferating and enter G1/G0 arrest. In t
Externí odkaz:
http://espace.library.uq.edu.au/view/UQ:180111
Autor:
Cassy, Spiller, Josephine, Bowles
Publikováno v:
Current topics in developmental biology. 134
Germ cells are the stem cells of the species. Thus, it is critical that we have a good understanding of how they are specified, how the somatic cells instruct and support them, how they commit to one or other sex, and how they ultimately develop into
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 245(4)
It is widely accepted that, during the development of testes in the mammalian embryo, male germ cells are influenced by signals from the surrounding somatic cells, but not vice versa, so that germ cells are dispensable for the formation of testes.We