Výsledky vyhledávání - "Cassio M. Fontes"

Ultrabright Fluorescence Readout of an Inkjet-Printed Immunoassay Using Plasmonic Nanogap Cavities

Autor: Jiani Huang, Daria Semeniak, Maiken H. Mikkelsen, Daniela F. Cruz, Angus Hucknall, Cassio M. Fontes, Ashutosh Chilkoti

Publikováno v: Nano Letters

Fluorescence-based microarrays are promising diagnostic tools due to their high throughput, small sample volume requirements, and multiplexing capabilities. However, their low fluorescence output has limited their implementation for in vitro diagnost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61af3734c1055b149ad5a2d92e5c193e
http://europepmc.org/articles/PMC7737629

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Smartphone Enabled Point-of-Care Detection of Serum Biomarkers

Autor: Jacob T, Heggestad, David S, Kinnamon, Jason, Liu, Daniel Y, Joh, Cassio M, Fontes, Qingshan, Wei, Aydogan, Ozcan, Angus M, Hucknall, Ashutosh, Chilkoti

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2393

Sandwich immunoassays are the gold standard for detection of protein analytes. Here, we describe an ultrasensitive point-of-care sandwich immunoassay platform for the detection of biomarkers directly from blood or serum using a custom-built smartphon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d806ea2b85182b8e161b2f39038f65c3
https://pubmed.ncbi.nlm.nih.gov/34837189

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Smartphone Enabled Point-of-Care Detection of Serum Biomarkers

Autor: David Kinnamon, Qingshan Wei, Aydogan Ozcan, Angus Hucknall, Jason Liu, Cassio M. Fontes, Daniel Y. Joh, Ashutosh Chilkoti, Jacob T Heggestad

Publikováno v: Methods in Molecular Biology ISBN: 9781071618028

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::baf53f8410068d2269218bc6a52939b9
https://doi.org/10.1007/978-1-0716-1803-5_19

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Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR

Autor: Patricia Shi, Krystle N. Agans, Daniel Y. Joh, Daniela F. Cruz, Thomas W. Geisbert, Carl F. Pieper, Maiken H. Mikkelsen, Michael D. Gunn, Cassio M. Fontes, Roarke Horstmeyer, Kelli M. Luginbuhl, Angus Hucknall, Stephanie L. Foster, Barbara D. Lipes, Garrett Kelly, Ashutosh Chilkoti, Jacob T Heggestad, Jason Liu, Aiwei Yan

Publikováno v: Sci Transl Med

Ebola virus (EBOV) hemorrhagic fever outbreaks have been challenging to deter due to the lack of health care infrastructure in disease-endemic countries and a corresponding inability to diagnose and contain the disease at an early stage. EBOV vaccine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affdf92021de03fbcf495ed93543ef49
https://doi.org/10.1126/scitranslmed.abd9696

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Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test

Publikováno v: medRxiv
article-version (status) pre
article-version (number) 1
Science Advances

A point-of-care, microfluidic platform detects antibodies against three SARS-CoV-2 antigens from blood in less than an hour.
Highly sensitive, specific, and point-of-care (POC) serological assays are an essential tool to manage coronavirus disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ddeb874b2e6c3492910efb52aaf668
https://pubmed.ncbi.nlm.nih.gov/33173900

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Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays

Autor: Somnath Bhattacharjee, Rohan K. Achar, Angus Hucknall, Ashutosh Chilkoti, Daniel Y. Joh, Cassio M. Fontes, Imran Ozer

Publikováno v: Langmuir. 35:1379-1390

Motivated by the lack of adventitious protein adsorption on zwitterionic polymer brushes that promise low noise and hence high analytical sensitivity for surface-based immunoassays, we explored their use as a substrate for immunoassay fabrication by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1b50b44014888e421ea9beaf23e2fa
https://doi.org/10.1021/acs.langmuir.8b01597

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Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood

Autor: Rohan K. Achar, Michael Freemark, Margaret L. Lund, Raluca Gordan, Rebecca Blair, Ryan T. Hill, Zackary Zimmers, Derek Tseng, Aydogan Ozcan, Qingshan Wei, Ashutosh Chilkoti, Cassio M. Fontes, Kelly A. Mason, Angus Hucknall, Daniel Y. Joh

The ELISA is the mainstay for sensitive and quantitative detection of protein analytes. Despite its utility, ELISA is time-consuming, resource-intensive, and infrastructure-dependent, limiting its availability in resource-limited regions. Here, we de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceb25aee749f5d070f84ac0f999e5ee
https://europepmc.org/articles/PMC5576789/

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Poly(oligo(ethylene glycol) methyl ether methacrylate) Brushes on High-κ Metal Oxide Dielectric Surfaces for Bioelectrical Environments

Autor: Rohan K. Achar, Joseph B. Andrews, Faris Albarghouthi, Benjamin B. Yellen, Felicia McGuire, Daniel Y. Joh, Rebecca Blair, Darush Mozhdehi, Cassio M. Fontes, Zackary Zimmers, William Oles, Aaron D. Franklin, Jacob Richter, Angus Hucknall, Roozbeh Abedini-Nassab, Ashutosh Chilkoti

Publikováno v: ACS applied materialsinterfaces. 9(6)

Advances in electronics and life sciences have generated interest in "lab-on-a-chip" systems utilizing complementary metal oxide semiconductor (CMOS) circuitry for low-power, portable, and cost-effective biosensing platforms. Here, we present a simpl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ad0823413a038cdfdc337a06f4f9ac
https://pubmed.ncbi.nlm.nih.gov/28117566

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