Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cassie-Marie Peigné"'
Autor:
Zsolt Sebestyen, Wouter Scheper, Anna Vyborova, Siyi Gu, Zuzana Rychnavska, Marleen Schiffler, Astrid Cleven, Coraline Chéneau, Martje van Noorden, Cassie-Marie Peigné, Daniel Olive, Robert Jan Lebbink, Rimke Oostvogels, Tuna Mutis, Gerrit Jan Schuurhuis, Erin J. Adams, Emmanuel Scotet, Jürgen Kuball
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1973-1985 (2016)
Human Vγ9Vδ2 T cells respond to tumor cells by sensing elevated levels of phosphorylated intermediates of the dysregulated mevalonate pathway, which is translated into activating signals by the ubiquitously expressed butyrophilin A1 (BTN3A1) throug
Externí odkaz:
https://doaj.org/article/2db78a3619e04870be1de1e42066352c
Publikováno v:
Cell and Gene Therapy Insights. :1215-1215
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2015, ⟨10.3389/fimmu.2014.00657⟩
Frontiers in Immunology, Vol 5 (2015)
Frontiers in Immunology, 2015, ⟨10.3389/fimmu.2014.00657⟩
Frontiers in Immunology, Frontiers, 2015, ⟨10.3389/fimmu.2014.00657⟩
Frontiers in Immunology, Vol 5 (2015)
Frontiers in Immunology, 2015, ⟨10.3389/fimmu.2014.00657⟩
International audience; In human beings, as well as in most non-human primates, the major peripheral γδ T cell subset, which accounts several percent of the whole lymphoid cells pool in adults, carries an heterodimeric TCR composed of Vγ9 and Vδ2
Autor:
James E. Crooks, Emmanuel Scotet, Richard Breathnach, Andrew Sandstrom, Cassie Marie Peigné, Marie Claude Gesnel, Alexandra Leger, Fabienne Konczak, Marc Bonneville, Erin J. Adams
Publikováno v:
Immunity. 40(4)
SummaryIn humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections, including Mycobacterium tuberculosis, through recognition of small pyrophosphate containing organic molecules known as phosphoantigens (pAgs). Key to pAg-mediated activat
Autor:
Erin J. Adams, Thomas Herrmann, Cassie-Marie Peigné, Jianqiang Li, Alexandra Leger, Jukka Mönkkönen, Richard Breathnach, Sonia Netzer, Yves Guillaume, Marc Bonneville, Christelle Harly, Daniel Olive, Emmanuel Scotet, Jürgen Kuball, Steven Nedellec, Hannu Mönkkönen, Julie Déchanet-Merville
Publikováno v:
Blood
Blood, 2012, 120 (11), pp.2269-2279. ⟨10.1182/blood-2012-05-430470⟩
Blood, 2012, 120 (11), pp.2269-2279. ⟨10.1182/blood-2012-05-430470⟩
Human peripheral Vγ9Vδ2 T cells are activated by phosphorylated metabolites (phosphoagonists [PAg]) of the mammalian mevalonate or the microbial desoxyxylulose-phosphate pathways accumulated by infected or metabolically distressed cells. The underl