Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cassie M. Chandler"'
Autor:
Jakob D. Shaykin, Lidia N. Olyha, Catherine E. Van Doorn, Joshua D. Hales, Cassie M. Chandler, Deann M. Hopkins, Kimberly Nixon, Joshua S. Beckmann, James R. Pauly, Michael T. Bardo
Publikováno v:
Drug and Alcohol Dependence Reports, Vol 12, Iss , Pp 100277- (2024)
Background: Alcohol use in adolescence may increase susceptibility to substance use disorders (SUDs) in adulthood. This study determined if voluntary ethanol (EtOH) consumption during adolescence, combined with social isolation, alters the trajectory
Externí odkaz:
https://doaj.org/article/e6cd4af6c9a849c3b547ab97e4c98949
Autor:
Jessica I. Wooden, Lauren E. Peacoe, Chinchusha Anasooya Shaji, Jennifer K. Melbourne, Cassie M. Chandler, Michael T. Bardo, Kimberly Nixon
Publikováno v:
Cells, Vol 12, Iss 21, p 2572 (2023)
During adolescence, the brain is highly susceptible to alcohol-induced damage and subsequent neuroimmune responses, effects which may enhance development of an alcohol use disorder (AUD). Neuroimmune reactions are implicated in adolescent alcohol exp
Externí odkaz:
https://doaj.org/article/59e18004e79a4d4590e0c0ac61e66216
Autor:
Cassie M, Chandler, Jakob D, Shaykin, Hui, Peng, James R, Pauly, Kimberly, Nixon, Michael T, Bardo
Publikováno v:
Alcohol. 104:13-21
Initiating alcohol use in adolescence significantly increases the likelihood of developing adult alcohol use disorder (AUD). However, it has been difficult to replicate adolescent alcohol exposure leading to increased adult alcohol intake across diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08588301d69d4b25b20cf55fcdef3f6a
https://doi.org/10.1016/j.alcohol.2022.07.008
https://doi.org/10.1016/j.alcohol.2022.07.008
Autor:
Michael T. Bardo, Cassie M. Chandler, Emily D. Denehy, Benjamin A. Carper, Mark A. Prendergast, Tracy L. Nolen
Publikováno v:
Experimental and clinical psychopharmacology.
There is comorbidity between posttraumatic stress disorder (PTSD) and opioid use disorder (OUD), perhaps because PTSD-like stressful experiences early in life alter the hypothalamic-pituitary-adrenal stress axis to increase the risk for OUD. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1300636a37b50fa963bb684eff1067c
https://pubmed.ncbi.nlm.nih.gov/35587421
https://pubmed.ncbi.nlm.nih.gov/35587421
Autor:
Jaren A. Reeves-Darby, Toufiqur Rahman, James M. Cook, Guanguan Li, Sherman A. Jones, Donna M. Platt, Cassie M. Chandler
Publikováno v:
Neuropharmacology
Preclinical evidence suggests a key role for GABA(A) receptors containing the α5 subunit (i.e., α5GABA(A) receptors) in the abuse-related effects of alcohol, including the reinforcing and discriminative stimulus effects, as well as cue-induced alco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f74d0d4ccd37ff3420cf38fa66e83b6
https://europepmc.org/articles/PMC8511242/
https://europepmc.org/articles/PMC8511242/
Autor:
Hui Peng, Catherine E. Van Doorn, Kimberly Nixon, Michael T. Bardo, Jennifer K. Melbourne, James R. Pauly, Cassie M. Chandler
Publikováno v:
Alcohol Clin Exp Res
Alcohol is one of the most widely used recreational substances worldwide, with drinking frequently initiated during adolescence. The developmental state of the adolescent brain makes it vulnerable to initiating alcohol use, often in high doses, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e89125f0ef3f500123cf8497c199429
https://europepmc.org/articles/PMC8793635/
https://europepmc.org/articles/PMC8793635/
Autor:
Toufiqur Rahman, Sherman A. Jones, Guanguan Li, J. Abigail McDonald, Jaren A. Reeves-Darby, James M. Cook, Cassie M. Chandler, Donna M. Platt
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: GABA(A) receptors containing the α5 subunit (i.e., α5GABA(A)) appear to be critically involved in the reinforcing and subjective effects of alcohol. Their role in alcohol relapse remains unknown. OBJECTIVES: Pharmacological approaches we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c6a8e71c7b9626f8f9767503ea87ef
https://doi.org/10.1007/s00213-018-5163-6
https://doi.org/10.1007/s00213-018-5163-6
Autor:
Cassie M. Chandler, Usman Hamid, Sarah E. Maggio, Hui Peng, James R. Pauly, Joshua Beckmann, Kimberly Nixon, Michael T. Bardo
Publikováno v:
Drug Alcohol Depend
BACKGROUND: Preclinical models simulating adolescent substance use leading to increased vulnerability for substance use disorders in adulthood are needed. Here, we utilized a model of alcohol and nicotine co-use to assess adult addiction vulnerabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e65ec943cded303a6c4d0556e50862f
https://doi.org/10.1016/j.drugalcdep.2022.109298
https://doi.org/10.1016/j.drugalcdep.2022.109298
Publikováno v:
Drug Alcohol Depend
Background As alcohol and nicotine use disorders are entwined, it may be possible to develop a single medication to treat both. We previously developed a model for ethanol (EtOH) and nicotine co-use in female selectively bred alcohol-preferring (P) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2459b23f31a220ca2d873fac3baa49
https://europepmc.org/articles/PMC7293937/
https://europepmc.org/articles/PMC7293937/
Autor:
Donna M. Platt, Sean Patterson, Ian Taylor, Cassie M. Chandler, Daniela Rüedi-Bettschen, Jemma E Cook
Publikováno v:
Psychol Addict Behav
Resurgence may be a mechanism of relapse in alcohol use disorder patients upon discharge from treatment as part of an abuse-treatment-relapse cycle. Adjunctive pharmacotherapies may be a means to facilitate behavioral treatments and block resurgence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4334acb44b50f86fb28234682b6d548a
https://pubmed.ncbi.nlm.nih.gov/31750701
https://pubmed.ncbi.nlm.nih.gov/31750701