Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cassie L. Albury"'
Autor:
Larisa M. Haupt, Alison Haywood, Heidi G. Sutherland, Chieh Yu, Cassie L. Albury, Anushka Pharasi, Mathew Zunk, Rani George, Lyn R. Griffiths, Phillip Good, Janet Hardy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Cancer pain is the most feared symptom at end of life. Methadone has advantages over other opioids but is associated with significant variability in clinical response, making dosing challenging in practice. OPRM1 is the most studied pharmaco
Externí odkaz:
https://doaj.org/article/d6837e2f2d844ba08dc46887310fae92
Autor:
Deniz Ozberk, Alison Haywood, Heidi G. Sutherland, Chieh Yu, Cassie L. Albury, Mathew Zunk, Rani George, Phillip Good, Lyn R. Griffiths, Janet Hardy, Larisa M. Haupt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Opioids are the therapeutic agents of choice to manage moderate to severe pain in patients with advanced cancer, however the unpredictable inter-individual response to opioid therapy remains a challenge for clinicians. While studies are few,
Externí odkaz:
https://doaj.org/article/bf9bdce28ad74f1da1d63fcf9f426c15
Publikováno v:
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-20 (2019)
Abstract Background Migraine is a complex neurovascular disorder with a strong genetic component. There are rare monogenic forms of migraine, as well as more common polygenic forms; research into the genes involved in both types has provided insights
Externí odkaz:
https://doaj.org/article/dafe263615d04503b3c5889dfe00de43
Autor:
Heidi G. Sutherland, Neven Maksemous, Cassie L. Albury, Omar Ibrahim, Robert A. Smith, Rod A. Lea, Larisa M. Haupt, Bronwyn Jenkins, Benjamin Tsang, Lyn R. Griffiths
Publikováno v:
Cells, Vol 9, Iss 11, p 2368 (2020)
Hemiplegic migraine (HM) is a rare migraine disorder with aura subtype including temporary weakness and visual, sensory, and/or speech symptoms. To date, three main genes—CACNA1A, ATP1A2, and SCN1A—have been found to cause HM. These encode ion ch
Externí odkaz:
https://doaj.org/article/25e3376889694022a9810496bcdda98f
Autor:
Gabrielle Bradshaw, Robbie R. Lualhati, Cassie L. Albury, Neven Maksemous, Deidre Roos-Araujo, Robert A. Smith, Miles C. Benton, David A. Eccles, Rod A. Lea, Heidi G. Sutherland, Larisa M. Haupt, Lyn R. Griffiths
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundWe investigated the molecular etiology of a young male proband with confirmed immunodeficiency of unknown cause, presenting with recurrent bacterial and Varicella zoster viral infections in childhood and persistent lymphopenia into early ad
Externí odkaz:
https://doaj.org/article/e148a543bbc64b79b57fc41d5690c2ab
Autor:
Paul Dunn, Cassie L. Albury, Neven Maksemous, Miles C. Benton, Heidi G. Sutherland, Robert A. Smith, Larisa M. Haupt, Lyn R. Griffiths
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Epilepsy is a neurological disorder characterized by an increased predisposition for seizures. Although this definition suggests that it is a single disorder, epilepsy encompasses a group of disorders with diverse aetiologies and outcomes. A genetic
Externí odkaz:
https://doaj.org/article/018577eecb6f41619c66c05871635f7d
Association of polymorphisms in ARRB2 and clinical response to methadone for pain in advanced cancer
Autor:
Deniz Ozberk, Alison Haywood, Heidi G Sutherland, Chieh Yu, Cassie L Albury, Mathew Zunk, Rani George, Phillip Good, Lyn R Griffiths, Janet Hardy, Larisa M Haupt
Publikováno v:
Pharmacogenomics. 23:281-289
Background: The prescription of methadone in advanced cancer poses multiple challenges due to the considerable interpatient variation seen in effective dose and toxicity. Previous reports have suggested that ARRB2 influences the response to methadone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd114b1bb5dba11b82a95c058efcdb1f
https://doi.org/10.2217/pgs-2021-0139
https://doi.org/10.2217/pgs-2021-0139
Autor:
Bridget H. Maher, Larisa M. Haupt, Robert A. Smith, Lyn R. Griffiths, Miles C. Benton, Paul J. Dunn, Shani Stuart, Cassie L. Albury, Neven Maksemous, Heidi G. Sutherland
Publikováno v:
Molecular Genetics and Genomics. 295:751-763
It is thought that despite highly variable phenotypic expression, 70-80% of all epileptic cases are caused by one or more genetic mutations. Next generation sequencing technologies, such as whole exome sequencing (WES), can be used in a diagnostic or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24827376b1a5353daa205108fd6d9b09
https://doi.org/10.1007/s00438-020-01657-x
https://doi.org/10.1007/s00438-020-01657-x
Autor:
Paul J. Dunn, Larisa M. Haupt, Neven Maksemous, Lyn R. Griffiths, Robert A. Smith, Miles C. Benton, Rodney A. Lea, Cassie L. Albury, Heidi G. Sutherland
Publikováno v:
The Journal of Molecular Diagnostics. 21:951-960
In this article, we introduce the variant call format–diagnostic annotation and reporting tool (VCF-DART), a customized analysis pipeline tool for the rapid annotation of variants from exome or genome sequencing and the generation of reports for ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52f6768a0ab5ff04e392d9855a38d8c7
https://doi.org/10.1016/j.jmoldx.2019.07.001
https://doi.org/10.1016/j.jmoldx.2019.07.001
Autor:
Neven Maksemous, Omar Ibrahim, Rod A. Lea, Cassie L. Albury, Larisa M. Haupt, Bronwyn Jenkins, Benjamin Tsang, Heidi G. Sutherland, Lyn R. Griffiths, Robert A. Smith
Publikováno v:
Cells
Cells, Vol 9, Iss 2368, p 2368 (2020)
Volume 9
Issue 11
Cells, Vol 9, Iss 2368, p 2368 (2020)
Volume 9
Issue 11
Hemiplegic migraine (HM) is a rare migraine disorder with aura subtype including temporary weakness and visual, sensory, and/or speech symptoms. To date, three main genes&mdash
CACNA1A, ATP1A2, and SCN1A&mdash
have been found to cause HM. T
CACNA1A, ATP1A2, and SCN1A&mdash
have been found to cause HM. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7547e8fa8927ea6b4390606fbe31f0
https://pubmed.ncbi.nlm.nih.gov/33126486
https://pubmed.ncbi.nlm.nih.gov/33126486