C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function

Autor: White, Michael R., Mitrea, Diana M., Zhang, Peipei, Stanley, Christopher B., Cassidy, Devon E., Nourse, Amanda, Phillips, Aaron H., Tolbert, Michele, Taylor, J. Paul, Kriwacki, Richard W.

Publikováno v: In Molecular Cell 16 May 2019 74(4):713-728

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Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs

Autor: Patel, Priyanka, Buchanan, Courtney N, Zdradzinski, Matthew D, Sahoo, Pabitra K, Kar, Amar N, Lee, Seung Joon, Vaughn, Lauren S, Urisman, Anatoly, Oses-Prieto, Juan, Dell'Orco, Michela, Cassidy, Devon E, Costa, Irene Dalla, Miller, Sharmina, Thames, Elizabeth, Smith, Terika P, Burlingame, Alma L, Perrone-Bizzozero, Nora, Twiss, Jeffery L

Publikováno v: Nucleic acids research, vol 50, iss 10

Axonally synthesized proteins support nerve regeneration through retrograde signaling and local growth mechanisms. RNA binding proteins (RBP) are needed for this and other aspects of post-transcriptional regulation of neuronal mRNAs, but only a limit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3b9f47963dad1d05f3c8574c4f4a5f26
https://escholarship.org/uc/item/8tc7r5j0

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Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs.

Autor: Patel P; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Buchanan CN; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Zdradzinski MD; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Sahoo PK; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Kar AN; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Lee SJ; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Vaughn LS; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Urisman A; Department of Pharmaceutical Sciences, University of California, San Francisco, CA 94143, USA., Oses-Prieto J; Department of Pharmaceutical Sciences, University of California, San Francisco, CA 94143, USA., Dell'Orco M; Department of Neurosciences, University of New Mexico School of Health Sciences, Albuquerque, NM 87131, USA., Cassidy DE; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Costa ID; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Miller S; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Thames E; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Smith TP; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA., Burlingame AL; Department of Pharmaceutical Sciences, University of California, San Francisco, CA 94143, USA., Perrone-Bizzozero N; Department of Neurosciences, University of New Mexico School of Health Sciences, Albuquerque, NM 87131, USA., Twiss JL; Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2022 Jun 10; Vol. 50 (10), pp. 5772-5792.