Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Cassia R, Overk"'
Autor:
Eliezer Masliah, Anjali Verma, Robert A. Rissman, Cassia R. Overk, Michelle A. Sallin, Changyoun Kim, Jyoti Misra Sen, Somin Kwon, Michiyo Iba, Ranjan Sen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background α-Synuclein (α-syn) is a pre-synaptic protein which progressively accumulates in neuronal and non-neuronal cells in neurodegenerative diseases such as Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c0e79212ce2ea1d264daac89ee8d51
http://link.springer.com/article/10.1186/s12974-020-01888-0
http://link.springer.com/article/10.1186/s12974-020-01888-0
Autor:
Cassia R. Overk, Pei-Yi Lu, Yue-Ting Wang, Jaewoo Choi, James W. Shaw, Gregory R. Thatcher, Elliott J. Mufson
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 1, Pp 479-487 (2012)
Alzheimer's disease (AD) is the most common form of dementia among the elderly with women exhibiting a higher risk than men for the disease. Due to these gender differences, there is great interest in the role that estrogens play in cognitive impairm
Externí odkaz:
https://doaj.org/article/37718f22f40e40c3bca7db730b1347fa
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 3, Pp 415-425 (2009)
The triple transgenic mouse (3xTgAD), harboring human APPSwe, PS1M146V and TauP301L genes, develops age-dependent forebrain intraneuronal Aβ and tau as well as extraneuronal plaques. We evaluated brainstem AD-like pathology using 6E10, AT8, and Alz5
Externí odkaz:
https://doaj.org/article/32dfba0fd40c4dcdaa09e2bc29e66e55
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617519
Alzheimer's disease (AD), Pick's disease, fronto-temporal lobar degeneration, cortico-basal degeneration, and primary age related tauopathy are examples of neurodegenerative disorders with tau accumulation and jointly referred as "tauopathies." The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de02842a2015906fc0addb1c99a86bbe
https://doi.org/10.1007/978-1-0716-1752-6_28
https://doi.org/10.1007/978-1-0716-1752-6_28
Autor:
Edward Rockenstein, Cassia R Overk, Kiren Ubhi, Michael Mante, Christina Patrick, Anthony Adame, Alejandro Bisquert, Margarita Trejo-Morales, Brian Spencer, Eliezer Masliah
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121570 (2015)
Tauopathies are a group of disorders leading to cognitive and behavioral impairment in the aging population. While four-repeat (4R) Tau is more abundant in corticobasal degeneration, progressive supranuclear palsy, and Alzheimer's disease, three-repe
Externí odkaz:
https://doaj.org/article/1433abc2c10e4f0c846ddeb51557504b
Publikováno v:
Journal of Alzheimer's Disease. 70:621-628
Dr. Robert Terry (January 14, 1924–May 20, 2017) studied normal aging and Alzheimer’s disease for more than five decades. He was at a visionary neuropathologist who trained generations of researchers in the field of neurodegenerative disorders an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cb9bcf61bd101c8aefa0cc18439f47
https://doi.org/10.3233/jad-190518
https://doi.org/10.3233/jad-190518
Autor:
Changyoun Kim, Sabine Schmidhuber, Gergana Galabova, Frank Mattner, Edward Rockenstein, Robert A. Rissman, Cassia R. Overk, Eliezer Masliah, Michael Mante, Brian Spencer, Radmila Santic, Markus Mandler, Anthony Adame, Achim Schneeberger, Jazmin Florio
Publikováno v:
Alzheimers Dement
Introduction Immunotherapeutic approaches targeting amyloid β (Aβ) protein and tau in Alzheimer's disease and α-synuclein (α-syn) in Parkinson's disease are being developed for treating dementia with Lewy bodies. However, it is unknown if single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1bf21164bf5da5efb16dd9c56e0b428
https://doi.org/10.1016/j.jalz.2019.02.002
https://doi.org/10.1016/j.jalz.2019.02.002
Publikováno v:
J Neurovirol
Journal of neurovirology, vol 25, iss 5
Journal of neurovirology, vol 25, iss 5
People over the age of 50 are the fastest growing segment of the HIV-infected population in the United States. Although antiretroviral therapy has remarkable success controlling the systemic HIV infection, HIV-associated neurocognitive disorder (HAND
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ffc1cbe3bca0ae07a8834c5a9c4e93
https://doi.org/10.1007/s13365-019-00728-z
https://doi.org/10.1007/s13365-019-00728-z
Autor:
William C. Mobley, Ahmad Salehi, Cassia R. Overk, Y. Eugene Yu, Kim Weldy, Eric Doran, Ann Becker, Ricardo Albay, Mariko Sawa, Thomas G. Beach, Dominique Derse, Elizabeth Head
Publikováno v:
Alzheimers Dement
Introduction People with Down syndrome (DS) are predisposed to Alzheimer's disease (AD). The amyloid hypothesis informs studies of AD. In AD-DS, but not sporadic AD, increased APP copy number is necessary, defining the APP gene dose hypothesis. Which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2c8233805b6592ad881ea5f0583d05
https://pubmed.ncbi.nlm.nih.gov/34757693
https://pubmed.ncbi.nlm.nih.gov/34757693
Autor:
Xu-Qiao Chen, Phuong Nguyen, William C. Mobley, Maria Maccecchini, Alexander M. Kleschevnikov, Matthew L. Pearn, Ahmad Salehi, Cassia R. Overk
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 17, iss 2
Alzheimer's & Dementia
Alzheimer's & Dementia
Objective Recent clinical trials targeting amyloid beta (Aβ) and tau in Alzheimer's disease (AD) have yet to demonstrate efficacy. Reviewing the hypotheses for AD pathogenesis and defining possible links between them may enhance insights into both u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691143f65dfced6635b43343f8af2cf7
https://escholarship.org/uc/item/4d04n1ns
https://escholarship.org/uc/item/4d04n1ns