Výsledky vyhledávání - "Cassia L. Braga"

Akademický článek

Comparison between sevoflurane and propofol on immunomodulation in an in vitro model of sepsis

Autor: Tainá B. Oliveira, Cassia L. Braga, Denise Battaglini, Paolo Pelosi, Patricia R. M. Rocco, Pedro L. Silva, Fernanda F. Cruz

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

IntroductionPatients with sepsis often require sedation and/or anesthesia. Although the immunomodulatory effects of anesthetics have been increasingly recognized, the molecular mechanisms require better elucidation. We compared the effects of sevoflu

Externí odkaz: https://doaj.org/article/275bf401bdd64340926606f7fed1f8d4

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Akademický článek

Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema

Autor: Mariana A. Antunes, Cassia L. Braga, Tainá B. Oliveira, Jamil Z. Kitoko, Ligia L. Castro, Debora G. Xisto, Mariana S. Coelho, Nazareth Rocha, Rodrigo P. Silva-Aguiar, Celso Caruso-Neves, Eduarda G. Martins, Clara Fernandes Carvalho, Antônio Galina, Daniel J. Weiss, José R. Lapa e Silva, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Patricia R. M. Rocco

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Although bone marrow-derived mesenchymal stromal cells (BM-MSCs) from patients with chronic obstructive pulmonary disease (COPD) appear to be phenotypically and functionally similar to BM-MSCs from healthy sources in vitro, the impact of COPD on MSC

Externí odkaz: https://doaj.org/article/8bef1ff43cb042c6abe44a3fba9bb1cc

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Akademický článek

Mesenchymal Stromal Cells Are More Effective Than Their Extracellular Vesicles at Reducing Lung Injury Regardless of Acute Respiratory Distress Syndrome Etiology

Autor: Johnatas D. Silva, Ligia L. de Castro, Cassia L. Braga, Gisele P. Oliveira, Stefano A. Trivelin, Carlos M. Barbosa-Junior, Marcelo M. Morales, Claudia C. dos Santos, Daniel J. Weiss, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Patricia R. M. Rocco

Publikováno v: Stem Cells International, Vol 2019 (2019)

Although mesenchymal stromal cells (MSCs) have demonstrated beneficial effects on experimental acute respiratory distress syndrome (ARDS), preconditioning may be required to potentiate their therapeutic effects. Additionally, administration of cell-f

Externí odkaz: https://doaj.org/article/aa66a863b23f49bc9563f5a35afdd5f4

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Time-Controlled Adaptive Ventilation Versus Volume-Controlled Ventilation in Experimental Pneumonia

Autor: Vera Luiza Capelozzi, Fernanda F. Cruz, Nader M. Habashi, Joshua Satalin, Adriana R. Silva, R.F. Magalhães, Cassia L. Braga, Mariana A. Antunes, Pedro L. Silva, Daniela G. da Cruz, Milena V. Oliveira, Marcos V. S. Fernandes, Penny Andrews, Roseli Vigio Ribeiro, Patricia R. M. Rocco, Cassiano F Gonçalves de-Albuquerque, Gary F. Nieman, Cynthia S. Samary

Publikováno v: Critical Care Medicine. 49:140-150

Objectives We hypothesized that a time-controlled adaptive ventilation strategy would open and stabilize alveoli by controlling inspiratory and expiratory duration. Time-controlled adaptive ventilation was compared with volume-controlled ventilation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a9915dff5cdcbdd2ad00cb6c1c259c
https://doi.org/10.1097/ccm.0000000000004675

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Effects of propofol and its formulation components on macrophages and neutrophils in obese and lean animals

Autor: Fernanda F. Cruz, Patricia R. M. Rocco, Rebecca Madureira Bose Leão, Soraia C. Abreu, Pedro L. Silva, Luciana Boavista Barros Heil, Lais Costa Agra, Mariana A. Antunes, Paolo Pelosi, Cassia L. Braga

Publikováno v: Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)

We hypothesized whether propofol or active propofol component (2,6‐diisopropylphenol [DIPPH] and lipid excipient [LIP‐EXC]) separately may alter inflammatory mediators expressed by macrophages and neutrophils in lean and obese rats. Male Wistar r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6699b27eab71b98aed320b1b0332dd8
http://europepmc.org/articles/PMC8503301

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Impact of positive biphasic pressure during low and high inspiratory efforts in Pseudomonas aeruginosa-induced pneumonia

Autor: Cassia L. Braga, Cassiano Felippe Gonçalves de Albuquerque, Cynthia S. Samary, R.F. Magalhães, Gisele A. Padilha, Mariana C. da Silva, Daniela G. da Cruz, Adriana R. Silva, Paolo Pelosi, Patricia R. M. Rocco, Pedro L. Silva, Vera Luiza Capelozzi

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246891 (2021)

Background During pneumonia, normal alveolar areas coexist adjacently with consolidated areas, and high inspiratory efforts may predispose to lung damage. To date, no study has evaluated different degrees of effort during Biphasic positive airway pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a73ff81b41ee9c959976e876839c4f
https://pubmed.ncbi.nlm.nih.gov/33577592

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Niclosamide attenuates lung vascular remodeling in experimental pulmonary arterial hypertension

Autor: Juliana Borges Vieira, Rebecca Madureira Bose, Patricia R. M. Rocco, Douglas E. Teixeira, Rodrigo P. Silva-Aguiar, Fernanda F. Cruz, Cassia L. Braga, Celso Caruso-Neves, Nathane S. Felix, Nazareth N. Rocha, Mariana A. Antunes, Pedro L. Silva

Publikováno v: European journal of pharmacology. 887

Despite advances in medical therapy, pulmonary arterial hypertension (PAH) remains an inexorably progressive and highly lethal disease. Signal transducer and activator of transcription (STAT)-3 is one of the main intracellular transcription factors i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40136f25506f3287082569ec007e3acc
https://pubmed.ncbi.nlm.nih.gov/32795515

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The renin–angiotensin–aldosterone system: Role in pathogenesis and potential therapeutic target in COVID-19

Autor: Diogo B. Peruchetti, Pedro L. Silva, Chiara Robba, Patricia R. M. Rocco, Denise Battaglini, Celso Caruso-Neves, Cassia L. Braga, Rodrigo P. Silva-Aguiar, Paolo Pelosi

Publikováno v: Pharmacology Research & Perspectives, Vol 8, Iss 4, Pp n/a-n/a (2020)
Pharmacology Research & Perspectives

Coronavirus disease 2019 (COVID‐19), caused by the SARS‐CoV‐2 novel coronavirus, has spread worldwide causing high fatality rates. Neither a vaccine nor specific therapeutic approaches are available, hindering the fight against this disease and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cb2bbb1328182141105893da8229f5
http://hdl.handle.net/11567/1029652

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Effects of pressure support ventilation on ventilator-induced lung injury in mild acute respiratory distress syndrome depend on level of positive end-expiratory pressure

Autor: Lillian Moraes, Paulo Magalhães, Cassia L. Braga, Robert Huhle, Cintia L. Santos, Maria do Carmo Duarte, Pedro L. Silva, Paolo Pelosi, Marcelo Gama de Abreu, Patricia R. M. Rocco, Gisele A. Padilha, Lívia Barboza de Andrade, Alberto Schanaider, Lígia de A. Maia, Vera L. Capellozzi

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Harmful effects of spontaneous breathing have been shown in experimental severe acute respiratory distress syndrome (ARDS). However, in the clinical setting, spontaneous respiration has been indicated only in mild ARDS. To date, no study has compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bffcc33ddce119d8bc012d9f67adfe1
https://doi.org/10.1097/eja.0000000000000763

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