Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cassi M. Bruni"'
Publikováno v:
International Journal of Medical Students, Vol 8, Iss 3 (2020)
Programmed cell death protein-1 (PD-1) is an immune checkpoint receptor that induces and maintains tolerance of T cells, invariant natural killer T (iNKT) cells, and natural killer (NK) cells, among other lymphocytes. Immune checkpoint inhibition by
Externí odkaz:
https://doaj.org/article/7827a54426134746ac05dc0fbe667c4d
Autor:
Verena M. Link, Martina P. Pasillas, Zhengyu Ouyang, Joseph L. Witztum, Christopher K. Glass, Xiaoli Sun, Anita Gola, Mojgan Hosseini, Hunter Bennett, Ty D. Troutman, David Gosselin, Mashito Sakai, Jeffrey G. McDonald, Jason S. Seidman, Kaori M. Ego, Cassi M. Bruni, BaoChau T. Vu, Ling-Wa Chong, Ronald N. Germain, Ronald M. Evans, Bonne M. Thompson, Nathanael J. Spann, Rick Z. Li
Publikováno v:
SSRN Electronic Journal.
Tissue resident macrophages and recruited monocyte-derived macrophages contribute to host defense but also play pathological roles in a diverse range of human diseases. Multiple macrophage phenotypes are often represented in a diseased tissue, but we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ac6ae818d394c133aac7d193aa3d25f
https://doi.org/10.2139/ssrn.3541367
https://doi.org/10.2139/ssrn.3541367
Autor:
Jason S. Seidman, Lorane Texari, Jonathan Chang, Jeffrey G. McDonald, Mashito Sakai, Zihou Deng, Nathanael J. Spann, Frederic Geissmann, Martina P. Pasillas, Hunter Bennett, Kaori M. Ego, Ty D. Troutman, Verena M. Link, Zhengyu Ouyang, Christopher K. Glass, Johannes C. M. Schlachetzki, Yohei Abe, Bonne M. Thompson, Sven Heinz, Bao Chau T. Vu, Cassi M. Bruni, Alexi Nott
Publikováno v:
Immunity, vol 51, iss 4
Tissue environment plays a powerful role in establishing and maintaining the distinct phenotypes of resident macrophages, but the underlying molecular mechanisms remain poorly understood. Here, we characterized transcriptomic and epigenetic changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1382c863a540136ed60572af76db97f6
https://pubmed.ncbi.nlm.nih.gov/31591534
https://pubmed.ncbi.nlm.nih.gov/31591534
Autor:
Mashito Sakai, Rick Z. Li, Nathanael J. Spann, Martina P. Pasillas, Jason S. Seidman, Cassi M. Bruni, Ty D. Troutman, Lorane Texari, Zhengyu Ouyang, Bao Chau T. Vu, Christopher K. Glass, Sven Heinz, Hunter Bennett, Kaori M. Ego
Publikováno v:
Journal of Investigative Dermatology. 140:S32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc7c79bc2849e892a62dabf244890e45
https://doi.org/10.1016/j.jid.2020.03.270
https://doi.org/10.1016/j.jid.2020.03.270
Autor:
Rick Z. Li, Ronald M. Evans, David Gosselin, Ty D. Troutman, Nathanael J. Spann, Martina P. Pasillas, Mojgan Hosseini, Bonne M. Thompson, Hunter Bennett, Verena M. Link, Zhengyu Ouyang, Jeffrey G. McDonald, Ronald N. Germain, Bao Chau T. Vu, Kaori M. Ego, Anita Gola, Mashito Sakai, Xiaoli Sun, Cassi M. Bruni, Ling Wa Chong, Jason S. Seidman, Christopher K. Glass, Joseph L. Witztum
Publikováno v:
Immunity, vol 52, iss 6
Immunity
Immunity
Tissue-resident and recruited macrophages contribute to both host defense and pathology. Multiple macrophage phenotypes are represented in diseased tissues, but we lack deep understanding of mechanisms controlling diversification. Here, we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b26572f341494c60eb8695f7b7d03ef
https://doi.org/10.1016/j.immuni.2020.04.001
https://doi.org/10.1016/j.immuni.2020.04.001
Autor:
Ty Dale Troutman, Jason S. Seidman, Mashito Sakai, Anita Gola, Zhengyu Ouyang, Nathanael J. Spann, Cassi M. Bruni, Hunter Bennett, Kaori Ego, BaoChau Vu, Xiaoli Sun, Martina Pasillas, Joseph L. Witztum, Ronald N. Germain, Christopher K. Glass
Publikováno v:
The Journal of Immunology. 202:59.2-59.2
Kupffer cells have specialized roles supporting the environment of the liver during homeostasis and disease. However, the key regulatory elements governing these behaviors are unknown. Using scRNA-seq, we found diversification of Kupffer cells and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e59b3d2763cbe654821fd163130cfdb
https://doi.org/10.4049/jimmunol.202.supp.59.2
https://doi.org/10.4049/jimmunol.202.supp.59.2
Autor:
Mashito Sakai, Ty Dale Troutman, Jason S. Seidman, Zhengyu Ouyang, Nathanael J. Spann, Yohei Abe, Kaori Ego, Cassi M. Bruni, Johannes C. M. Schlachetzki, Alexi Nott, Hunter Bennett, Jonathan Chang, BaoChau T. Vu, Martina Pasillas, Verena M. Link, Lorane Texari, Sven Heinz, Christopher K. Glass
Publikováno v:
The Journal of Immunology. 202:187.21-187.21
Functional specialization of tissue resident macrophages occurs through environmental signals controlling activity and/or expression of transcription factors. Kupffer cells are resident macrophages in the hepatic sinusoids and have critical roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5288c191323970e3caa88f3d5447ff
https://doi.org/10.4049/jimmunol.202.supp.187.21
https://doi.org/10.4049/jimmunol.202.supp.187.21