Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cassaundra L. Ameel"'
Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques
Autor:
Caylin G. Winchell, Bibhuti B. Mishra, Jia Yao Phuah, Mohd Saqib, Samantha J. Nelson, Pauline Maiello, Chelsea M. Causgrove, Cassaundra L. Ameel, Brianne Stein, H. Jacob Borish, Alexander G. White, Edwin C. Klein, Matthew D. Zimmerman, Véronique Dartois, Philana Ling Lin, Christopher M. Sassetti, JoAnne L. Flynn
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In 2017 over 550,000 estimated new cases of multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) occurred, emphasizing a need for new treatment strategies. Linezolid (LZD) is a potent antibiotic for drug-resistant Gram-positive infections and is
Externí odkaz:
https://doaj.org/article/cb9c7db12abd401b9c0a88eb06a4e51b
Autor:
Ebene R Haycroft, Timon Damelang, Ester Lopez, Mark A Rodgers, Bruce D Wines, Mark Hogarth, Cassaundra L Ameel, Stephen J Kent, Charles A Scanga, Shelby L O'Connor, Amy W Chung
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Objectives Tuberculosis (TB) remains a substantial cause of morbidity and mortality among people living with human immunodeficiency virus (HIV) worldwide. However, the immunological mechanisms associated with the enhanced susceptibility amon
Externí odkaz:
https://doaj.org/article/4a87f15db7084ad890bf9bc3adf4e697
Autor:
Erica C. Larson, Amy L. Ellis, Mark A. Rodgers, Abigail K. Gubernat, Janelle L. Gleim, Ryan V. Moriarty, Alexis J. Balgeman, Yonne K. Menezes, Cassaundra L. Ameel, Daniel J. Fillmore, Skyler M. Pergalske, Jennifer A. Juno, Pauline Maiello, Alexander G. White, H. Jacob Borish, Dale I. Godfrey, Stephen J. Kent, Lishomwa C. Ndhlovu, Shelby L. O’Connor, Charles A. Scanga
Publikováno v:
Infection and Immunity. 91
Pre-existing HIV infection increases tuberculosis (TB) risk in children. Antiretroviral therapy (ART) reduces, but does not abolish, this risk in children with HIV.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172adcaad3e8215a412007bdcdad27f3
https://doi.org/10.1128/iai.00558-22
https://doi.org/10.1128/iai.00558-22
Autor:
Erica C. Larson, Amy L. Ellis, Mark A. Rodgers, Abigail K. Gubernat, Janelle L. Gleim, Ryan V. Moriarty, Alexis J. Balgeman, Yonne K. Menezes, Cassaundra L. Ameel, Daniel J. Fillmore, Skyler M. Pergalske, Jennifer A. Juno, Pauline Maiello, Alexander G. White, H. Jacob Borish, Dale I. Godfrey, Stephen J. Kent, Lishomwa C. Ndhlovu, Shelby L. O’Connor, Charles A. Scanga
Pre-existing HIV infection increases tuberculosis (TB) risk in children. Antiretroviral therapy (ART) reduces, but does not abolish, this risk in children with HIV. The immunologic mechanisms involved in TB progression in both HIV-naïve and HIV-infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741f374e2e2ee5f6f6b5e43dc6310405
https://doi.org/10.1101/2022.12.14.520525
https://doi.org/10.1101/2022.12.14.520525
Autor:
Erica C, Larson, Amy, Ellis-Connell, Mark A, Rodgers, Alexis J, Balgeman, Ryan V, Moriarty, Cassaundra L, Ameel, Tonilynn M, Baranowski, Jaime A, Tomko, Chelsea M, Causgrove, Pauline, Maiello, Shelby L, O'Connor, Charles A, Scanga
Publikováno v:
J Immunol
Tuberculosis (TB) is the leading infectious cause of death among people living with HIV (PLHIV). PLHIV are more susceptible to contracting Mycobacterium tuberculosis (Mtb) and often have worsened TB disease. Understanding the immunologic defects caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::016b332defc3d9a3afcc0ca7f1eeda10
https://pubmed.ncbi.nlm.nih.gov/34145063
https://pubmed.ncbi.nlm.nih.gov/34145063
The role of lymphocyte subsets in preventing tuberculosis following intravenous vaccination with BCG
Autor:
Andrew W Simonson, Allison N Bucsan, Joseph J Zeppa, Caylin G Winchell, Amy J Myers, Matthew Sutton, Cassaundra L Ameel, Patricia A Darrah, Mario Roederer, Robert A Seder, JoAnne L Flynn
Publikováno v:
The Journal of Immunology. 208:181.11-181.11
Background We previously demonstrated in non-human primates (NHP) that intravenous (IV) administration of BCG induces substantial T cell responses and often sterilizing immunity against Mycobacterium tuberculosis (Mtb) infection. Here, we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fe046269709b0eb13d648706123b50f
https://doi.org/10.4049/jimmunol.208.supp.181.11
https://doi.org/10.4049/jimmunol.208.supp.181.11
Autor:
Hannah P. Gideon, Travis K. Hughes, Constantine N. Tzouanas, Marc H. Wadsworth, Ang Andy Tu, Todd M. Gierahn, Joshua M. Peters, Forrest F. Hopkins, Jun-Rong Wei, Conner Kummerlowe, Nicole L. Grant, Kievershen Nargan, Jia Yao Phuah, H. Jacob Borish, Pauline Maiello, Alexander G. White, Caylin G. Winchell, Sarah K. Nyquist, Sharie Keanne C. Ganchua, Amy Myers, Kush V. Patel, Cassaundra L. Ameel, Catherine T. Cochran, Samira Ibrahim, Jaime A. Tomko, Lonnie James Frye, Jacob M. Rosenberg, Angela Shih, Michael Chao, Edwin Klein, Charles A. Scanga, Jose Ordovas-Montanes, Bonnie Berger, Joshua T. Mattila, Rajhmun Madansein, J. Christopher Love, Philana Ling Lin, Alasdair Leslie, Samuel M. Behar, Bryan Bryson, JoAnne L. Flynn, Sarah M. Fortune, Alex K. Shalek
Publikováno v:
Immunity. 55:827-846.e10
Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the granuloma. In some granulomas, immune activity promotes bacterial clearance, but in others, bacteria persist and grow. We identified correlates of bacterial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4751cc76c4a7d51734d0705b3934fa
https://doi.org/10.1016/j.immuni.2022.04.004
https://doi.org/10.1016/j.immuni.2022.04.004
Autor:
Hannah P. Gideon, Travis K. Hughes, Constantine N. Tzouanas, Marc H. Wadsworth, Ang Andy Tu, Todd M. Gierahn, Joshua M. Peters, Forrest F. Hopkins, Jun-Rong Wei, Conner Kummerlowe, Nicole L. Grant, Kievershen Nargan, Jia Yao Phuah, H. Jacob Borish, Pauline Maiello, Alexander G. White, Caylin G. Winchell, Sarah K. Nyquist, Sharie Keanne C. Ganchua, Amy Myers, Kush V Patel, Cassaundra L. Ameel, Catherine T. Cochran, Samira Ibrahim, Jaime A Tomko, Lonnie James Frye, Jacob M. Rosenberg, Angela Shih, Michael Chao, Charles A. Scanga, Jose Ordovas-Montanes, Bonnie Berger, Joshua T. Mattila, Rajhmun Madansein, J. Christopher Love, Philana Ling Lin, Alasdair Leslie, Samuel M. Behar, Bryan Bryson, JoAnne L Flynn, Sarah M. Fortune, Alex K. Shalek
Mycobacterium tuberculosis lung infection results in a complex multicellular structure, the granuloma. In some granulomas, immune activity promotes bacterial clearance; in others, bacteria persist and grow. We identified correlates of bacterial contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7560139895ed4573b1d19bd67d012bd6
https://doi.org/10.1101/2020.10.24.352492
https://doi.org/10.1101/2020.10.24.352492
Autor:
Erica C Larson, Mark A Rodgers, Amy L Ellis, Cassaundra L Ameel, Janelle L Gleim, Abigail K Gubernat, Alexis Balgeman, Ryan V Moriarty, Patricia A Darrah, Pauline Maiello, Mario Roederer, Robert A Seder, Shelby L O’Connor, Charles A Scanga
Publikováno v:
The Journal of Immunology. 206:59.11-59.11
Tuberculosis is the most common cause of death due to infection in people living with HIV (PLHIV). BCG, a live attenuated Mycobacterium bovis strain given intradermally to infants, is the only licensed vaccine to prevent TB. However, intradermal BCG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e587201488243eb8399ab4b6624c8e8
https://doi.org/10.4049/jimmunol.206.supp.59.11
https://doi.org/10.4049/jimmunol.206.supp.59.11
Autor:
Erica C Larson, Mark A Rodgers, Amy L Ellis, Cassaundra L Ameel, Tonilynn M Baranowski, Alexis J Balgeman, Pauline A Maiello, Shelby L O’Connor, Charles A Scanga
Publikováno v:
The Journal of Immunology. 202:190.36-190.36
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the leading cause of death among HIV+ individuals. The precise mechanisms by which HIV impairs the immune response to subsequent Mtb infection are unknown. We previously established a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f8ecf4123c5c4fb47a76977081a819
https://doi.org/10.4049/jimmunol.202.supp.190.36
https://doi.org/10.4049/jimmunol.202.supp.190.36