Benign Breast Disease and the Risk of Breast Cancer

Autor: Vera J. Suman, Karthik Ghosh, Cassann Blake, Celine M. Vachon, Daniel W. Visscher, Lynn C. Hartmann, Thea D. Tlsty, V. Shane Pankratz, Robert A. Vierkant, Wilma L. Lingle, Amy C. Degnim, L. Joseph Melton, Jo Johnson, David W. Hillman, Thomas A. Sellers, Shaun D. Maloney, Marlene H. Frost

Publikováno v: The New England journal of medicine, vol 353, iss 3
Obstetrical & Gynecological Survey, vol 71, iss 8
Obstetrical and Gynecological Survey, vol 71, iss 8

BACKGROUND Benign breast disease is an important risk factor for breast cancer. We studied a large group of women with benign breast disease to obtain reliable estimates of this risk. METHODS We identified all women who received a diagnosis of benign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59271437303536be97708d6b8f30ccf2
https://doi.org/10.1097/01.ogx.0000489578.68399.d7

Granulocyte-macrophage colony-stimulating factor and interferon-γ prevent dexamethasone-induced immunosuppression of antifungal monocyte activity againstAspergillus fumigatushyphae

Autor: P.A. Pizzo, Thomas J. Walsh, Andrew Holmes, Cassann Blake, Emmanuel Roilides

Publikováno v: Medical Mycology. 34:63-69

Treatment with corticosteroids is an important risk factor for development of invasive aspergillosis. We evaluated the effect of dexamethasone (DEX) on superoxide anion (O2-) release and damage caused by elutriated human monocytes (EHM) on unopsonize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f3c9afebd0491024f19480737bf7b45
https://doi.org/10.1080/02681219680000101

Effects of granulocyte colony-stimulating factor and interferon-γ on antifungal activity of human polymorphonuclear neutrophils against pseudohyphae of different medically important Candida species

Autor: Andrew Holmes, Emmanuel Roilides, Thomas J. Walsh, Cassann Blake, Philip A. Pizzo

Publikováno v: Journal of Leukocyte Biology. 57:651-656

Polymorphonuclear neutrophils (PMNs) are the major host defense against pseudohyphae, the inva sive form of Candida species. We studied the effects of granulocyte colony-stimulating factor (G-CSF) and interfcron-γ (IFN-γ) on the PMN-induced damage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ed2313c1f75b04748bc823f009c5c8
https://doi.org/10.1002/jlb.57.4.651

Defective Antifungal Activity of Monocyte-Derived Macrophages from Human Immunodeficiency Virus-Infected Children against Aspergillus fumigatus

Autor: Thomas J. Walsh, Emmanuel Roilides, Philip A. Pizzo, Cassann Blake, Andrew Holmes

Publikováno v: Journal of Infectious Diseases. 168:1562-1565

Invasive aspergillosis recently has been encountered in adults and children with human immunodeficiency virus (HIV) infection even without known risk factors, such as neutropenia or corticosteroid therapy. Macrophages play a significant role in the h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47c6365c4e2b1d6e1e4ebea44d85118
https://doi.org/10.1093/infdis/168.6.1562

Obesity is Associated with Atypia in Breast Ductal Lavage of Women with Proliferative Breast Disease

Autor: Lance K. Heilbrun, Shashi Madan, Matthew S. Koletsky, Ann Edwards, Jianwei Ren, Zora Djuric, L. L. Darga, Cassann Blake

Background: Benign proliferative breast disease without atypia slightly increases breast cancer risk but there are currently few clinical options for breast cancer prevention in this group of women. Methods: We conducted a pilot study of women with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c3e6cb9cd2551bc7b0a396c9656d1c
https://europepmc.org/articles/PMC2763034/