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pro vyhledávání: '"Cassandra Terry"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6987 (2024)
The number of people diagnosed with type 2 diabetes is on the increase worldwide. Of growing concern, the prevalence of type 2 diabetes in children and youths is increasing rapidly and mirrors the increasing burden of childhood obesity. There are man
Externí odkaz:
https://doaj.org/article/2306ded7ff4d4bee9c76356866a19d9d
Autor:
Cassandra Terry
Publikováno v:
Current Research in Biotechnology, Vol 2, Iss , Pp 131-144 (2020)
Protein misfolding is fundamental to a number of human disorders including Alzheimer’s disease, prion diseases, Parkinson’s disease and type 2 diabetes mellitus. To date, there are still no cures for protein misfolding disorders. This is due to o
Externí odkaz:
https://doaj.org/article/29dc05c1208749389551565bc61ac5de
Autor:
Fiona French, Cassandra Terry, Saif Huq, Isaac Furieri, Mateusz Jarzembinski, Simas Pauliukenas, Neil Morrison, Karen Shepherd
Publikováno v:
Multimodal Technologies and Interaction, Vol 6, Iss 9, p 78 (2022)
Here we describe a proof-of-concept case study focusing on the design and development of a novel computer interface that uses facial muscles to control interactivity within a virtual environment. We have developed a system comprised of skin-mounted e
Externí odkaz:
https://doaj.org/article/3447fa56386a4795abcde0989bcfc77b
Publikováno v:
Life, Vol 12, Iss 4, p 583 (2022)
Cases of Type 2 Diabetes Mellitus (T2DM) are increasing at an alarming rate due to the rise in obesity, sedentary lifestyles, glucose-rich diets and other factors. Numerous studies have increasingly illustrated the pivotal role that human islet amylo
Externí odkaz:
https://doaj.org/article/c56cdde1679c4ea88792615e39b55d01
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Prions are lethal pathogens, which cause fatal neurodegenerative diseases in mammals. They are unique infectious agents and are composed of self-propagating multi-chain assemblies of misfolded host-encoded prion protein (PrP). Understanding prion str
Externí odkaz:
https://doaj.org/article/9239cd6e87034867bea517f2eeafecf4
Autor:
Claire J. Sarell, Emma Quarterman, Daniel C.-M. Yip, Cassandra Terry, Andrew J. Nicoll, Jonathan D. F. Wadsworth, Mark A. Farrow, Dominic M. Walsh, John Collinge
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Mammalian prions cause lethal neurodegenerative diseases such as Creutzfeldt–Jakob disease (CJD) and consist of multi-chain assemblies of misfolded cellular prion protein (PrPC). Ligands that bind to PrPC can inhibit prion propagation and neurotoxi
Externí odkaz:
https://doaj.org/article/229b8c2701a0414b8a25fe465d116345
Autor:
Cassandra Terry, Adam Wenborn, Nathalie Gros, Jessica Sells, Susan Joiner, Laszlo L. P. Hosszu, M. Howard Tattum, Silvia Panico, Daniel K. Clare, John Collinge, Helen R. Saibil, Jonathan D. F. Wadsworth
Publikováno v:
Open Biology, Vol 6, Iss 5 (2016)
Mammalian prions are hypothesized to be fibrillar or amyloid forms of prion protein (PrP), but structures observed to date have not been definitively correlated with infectivity and the three-dimensional structure of infectious prions has remained ob
Externí odkaz:
https://doaj.org/article/66baab80ced54423ba33dae7af2b24e3
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23801 (2011)
In members of the Bacillus cereus group the outermost layer of the spore is the exosporium, which interacts with hosts and the environment. Efforts have been made to identify proteins of the exosporium but only a few have so far been characterised an
Externí odkaz:
https://doaj.org/article/0fe75b4391204a3287185554b1002a1f
Publikováno v:
Bioscience Reports. 42
There are over 40 identified human disorders that involve certain proteins folding incorrectly, accumulating in the body causing damage to cells and organs and causing disease. Type 2 Diabetes Mellitus (T2DM) is one of these protein misfolding disord
Autor:
Parmjit S. Jat, Huda Al-Doujaily, Aline T Marinho, Jonathan D. F. Wadsworth, Madeleine Reilly, Iryna Benilova, Adam Wenborn, Emmanuel Risse, Christian Schmidt, Michael Wiggins De Oliveira, Cassandra Terry, John Collinge, Malin K. Sandberg
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Prions are infectious agents composed of polymers of misfolded prion protein which cause fatal brain diseases such as Creutzfeldt–Jakob disease. These diseases involve progressive loss of neuronal cells, and it has been long assumed th