Zobrazeno 1 - 5
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pro vyhledávání: '"Cassandra R, Edgar"'
Autor:
Steven M. Trothen, Jack E. Teplitsky, Ryan E. Armstong, Rong Xuan Zang, Antony Lurie, Mitchell J. Mumby, Cassandra R. Edgar, Matthew W. Grol, Jimmy D. Dikeakos
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 35014-35027 (2024)
Externí odkaz:
https://doaj.org/article/8db81e63a0864d3d810cfdfc063a61a1
Autor:
Cassandra R, Edgar, Jimmy D, Dikeakos
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2440
Examining protein-protein interactions provides critical insight into numerous human diseases and infections. Here we describe a protocol for bimolecular fluorescence complementation, which can be used to directly visualize and characterize intracell
Autor:
Jimmy D. Dikeakos, Cassandra R Edgar, Andrés Finzi, S. M. Mansour Haeryfar, Alexa Galbraith, Jérémie Prévost, Mitchell J. Mumby, Rajesh Abraham Jacob, Frank Kirchhoff, Antony Lurie, Steven M. Trothen
Publikováno v:
The Journal of Biological Chemistry
Prolonged immune activation drives the upregulation of multiple checkpoint receptors on the surface of virus-specific T cells, inducing their exhaustion. Reversing HIV-1-induced T cell exhaustion is imperative for efficient virus clearance; however,
Autor:
Cassandra R Edgar, Jimmy D. Dikeakos, Steven M. Trothen, Aaron L. Johnson, Eric J. Arts, Mitchell J. Mumby, Peter B. Stathopulos, Richard M. Gibson
Publikováno v:
J Virol
Serine incorporator 5 (SERINC5) reduces the infectivity of progeny HIV-1 virions by incorporating into the outer host-derived viral membrane during egress. To counter SERINC5, the HIV-1 accessory protein Nef triggers SERINC5 internalization by engagi
Autor:
Jérémie, Prévost, Cassandra R, Edgar, Jonathan, Richard, Steven M, Trothen, Rajesh Abraham, Jacob, Mitchell J, Mumby, Suzanne, Pickering, Mathieu, Dubé, Daniel E, Kaufmann, Frank, Kirchhoff, Stuart J D, Neil, Andrés, Finzi, Jimmy D, Dikeakos
Publikováno v:
J Virol
Along with other immune checkpoints, T cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) is expressed on exhausted CD4(+) and CD8(+) T cells and is upregulated on the surface of these cells upon infection by human immunodeficiency vir