Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Cassandra M. Kerr"'
Autor:
Yasunobu Nagata, Hideki Makishima, Cassandra M. Kerr, Bartlomiej P. Przychodzen, Mai Aly, Abhinav Goyal, Hassan Awada, Mohammad Fahad Asad, Teodora Kuzmanovic, Hiromichi Suzuki, Tetsuichi Yoshizato, Kenichi Yoshida, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Satoru Miyano, Sudipto Mukherjee, Thomas LaFramboise, Aziz Nazha, Mikkael A. Sekeres, Tomas Radivoyevitch, Torsten Haferlach, Seishi Ogawa, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Stepwise acquisition of mutations gives rise to myelodysplastic syndrome (MDS) in older adults. Here, the authors infer the clonal hierarchy of 1809 MDS patients, revealing insights into the evolution of dominant/secondary mutations and how these imp
Externí odkaz:
https://doaj.org/article/37f1f1df587f487aa52451ea6ac3c346
Autor:
Simona Pagliuca, Carmelo Gurnari, Sanghee Hong, Ran Zhao, Sunisa Kongkiatkamon, Laila Terkawi, Misam Zawit, Yihong Guan, Hassan Awada, Ashwin Kishtagari, Cassandra M. Kerr, Thomas LaFramboise, Bhumika J. Patel, Babal K. Jha, Hetty E. Carraway, Valeria Visconte, Navneet S. Majhail, Betty K. Hamilton, Jaroslaw P. Maciejewski
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
TCR repertoire diversification constitutes a foundation for successful immune reconstitution after allogeneic hematopoietic cell transplantation (allo-HCT). Deep TCR Vβ sequencing of 135 serial specimens from a cohort of 35 allo-HCT recipients/donor
Externí odkaz:
https://doaj.org/article/720a398ed82f4d6bab113a63c1654381
Autor:
Teodora Kuzmanovic, Bhumika J. Patel, Srinivasa R. Sanikommu, Yasunobu Nagata, Hassan Awada, Cassandra M. Kerr, Bartlomiej P. Przychodzen, Babal K. Jha, Devendra Hiwase, Deepak Singhal, Anjali S. Advani, Aziz Nazha, Aaron T. Gerds, Hetty E. Carraway, Mikkael A. Sekeres, Sudipto Mukherjee, Jaroslaw P. Maciejewski, Tomas Radivoyevitch
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/f2f20fbf1c004806942e297036a8c6ec
Autor:
Seishi Ogawa, Hideki Makishima, Akifumi Takaori-Kondo, Lee-Yung Shih, Felicitas Thol, Michael Heuser, Arnold Ganser, Kazuma Ohyashiki, Takayuki Ishikawa, Jaroslaw P. Maciejewski, Shuichi Miyawaki, Hisashi Tsurumi, Nobuo Sezaki, Kensuke Usuki, Toshiyuki Kitano, Yasushi Miyazaki, Shigeru Chiba, Satoru Miyano, Ken Ishiyama, Hideyuki Nakazawa, Akira Hangaishi, Nobuhiro Hiramoto, Daisuke Morishita, Yasunobu Nagata, Cassandra M. Kerr, Ming-Chung Kuo, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Chiba, Ayana Kon, Takuto Mori, Xingxing Qi, Rurika Okuda, Lanying Zhao, Yotaro Ochi, Ryunosuke Saiki, Akinori Yoda, Yasuhito Nannya, Masahiro M. Nakagawa, Kenichi Yoshida, June Takeda
Acute erythroid leukemia (AEL) is a unique subtype of acute myeloid leukemia characterized by prominent erythroid proliferation whose molecular basis is poorly understood. To elucidate the underlying mechanism of erythroid proliferation, we analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a93ec3045451fa3ff7b29a983e4abd
https://doi.org/10.1158/2643-3230.c.6550902.v1
https://doi.org/10.1158/2643-3230.c.6550902.v1
Autor:
Seishi Ogawa, Hideki Makishima, Akifumi Takaori-Kondo, Lee-Yung Shih, Felicitas Thol, Michael Heuser, Arnold Ganser, Kazuma Ohyashiki, Takayuki Ishikawa, Jaroslaw P. Maciejewski, Shuichi Miyawaki, Hisashi Tsurumi, Nobuo Sezaki, Kensuke Usuki, Toshiyuki Kitano, Yasushi Miyazaki, Shigeru Chiba, Satoru Miyano, Ken Ishiyama, Hideyuki Nakazawa, Akira Hangaishi, Nobuhiro Hiramoto, Daisuke Morishita, Yasunobu Nagata, Cassandra M. Kerr, Ming-Chung Kuo, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Chiba, Ayana Kon, Takuto Mori, Xingxing Qi, Rurika Okuda, Lanying Zhao, Yotaro Ochi, Ryunosuke Saiki, Akinori Yoda, Yasuhito Nannya, Masahiro M. Nakagawa, Kenichi Yoshida, June Takeda
Supplementary Figure from Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9319fb1c74d5594ca439a7f9481dc60d
https://doi.org/10.1158/2643-3230.22545315
https://doi.org/10.1158/2643-3230.22545315
Autor:
Seishi Ogawa, Hideki Makishima, Akifumi Takaori-Kondo, Lee-Yung Shih, Felicitas Thol, Michael Heuser, Arnold Ganser, Kazuma Ohyashiki, Takayuki Ishikawa, Jaroslaw P. Maciejewski, Shuichi Miyawaki, Hisashi Tsurumi, Nobuo Sezaki, Kensuke Usuki, Toshiyuki Kitano, Yasushi Miyazaki, Shigeru Chiba, Satoru Miyano, Ken Ishiyama, Hideyuki Nakazawa, Akira Hangaishi, Nobuhiro Hiramoto, Daisuke Morishita, Yasunobu Nagata, Cassandra M. Kerr, Ming-Chung Kuo, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Chiba, Ayana Kon, Takuto Mori, Xingxing Qi, Rurika Okuda, Lanying Zhao, Yotaro Ochi, Ryunosuke Saiki, Akinori Yoda, Yasuhito Nannya, Masahiro M. Nakagawa, Kenichi Yoshida, June Takeda
Supplementary Table from Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1b0b535b90c3612802e56e3a46929d
https://doi.org/10.1158/2643-3230.22545312
https://doi.org/10.1158/2643-3230.22545312
Autor:
Metis Hasipek, Cassandra M Kerr, Vera Adema, Babal K. Jha, Yihong Guan, Daniel J. Lindner, Anand D. Tiwari, Manja Meggendorfer, Tomas Radivoyevitch, Mohamed E. Abazeed, Dale Grabowski, Yvonne Parker, Priyanka Gopal, Omar Y. Mian, Jaroslaw P. Maciejewski, Mikkeal A. Sekeres, Simona Pagliuca, James G. Phillips, Torsten Haferlach
Publikováno v:
Blood Cancer Discov
TET2 is frequently mutated in myeloid neoplasms. Genetic TET2 deficiency leads to skewed myeloid differentiation and clonal expansion, but minimal residual TET activity is critical for survival of neoplastic progenitor and stem cells. Consistent with
Autor:
Nathan Radakovich, Manja Meggendorfer, Luca Malcovati, Mikkael A. Sekeres, Jacob Shreve, Cameron Beau Hilton, Yazan Rouphail, Wencke Walter, Stephan Hutter, Sudipto Mukherjee, Cassandra M. Kerr, Babal K. Jha, Anna Gallì, Sarah Pozzi, Aaron T. Gerds, Cassandra M Kerr, Claudia Haferlach, Jaroslaw P. Maciejewski, Torsten Haferlach, Aziz Nazha
Publikováno v:
Blood. 136:33-35
Background While histo- and cytomorphological examinations are central to the diagnosis of myelodysplastic syndromes (MDS), significant inter-observer variability exists. The diagnosis can be challenging in pancytopenic patients (pts) without evidenc
Autor:
Hassan Awada, Brian P. Hobbs, Jacob G. Scott, Sunisa Kongkiatkamon, Aziz Nazha, Jaroslaw P. Maciejewski, Tomas Radivoyevitch, Yasunobu Nagata, Inom Mirzaev, Ran Zhao, Mikkael A. Sekeres, Hideki Makishima, Cassandra M Kerr
Publikováno v:
Blood. 136:2249-2262
Morphologic interpretation is the standard in diagnosing myelodysplastic syndrome (MDS), but it has limitations, such as varying reliability in pathologic evaluation and lack of integration with genetic data. Somatic events shape morphologic features
Autor:
Yazan F. Madanat, Teodora Kuzmanovic, Sudipto Mukherjee, Heesun J. Rogers, Anjali S. Advani, Aaron T. Gerds, Bhumika J. Patel, Yasunobu Nagata, Mikkael A. Sekeres, Yogen Saunthararajah, Cassandra M Kerr, Aziz Nazha, Jennifer S. Carew, Steffan T. Nawrocki, Hetty E. Carraway, Francesc Solé, Valeria Visconte, Ying Ni, Jack Khouri, Hassan Awada, Vera Adema, Jaroslaw P. Maciejewski
Publikováno v:
Leukemia & Lymphoma. 62:735-738
Here we investigate single codon SF3B1 mutations (K700E, K666, H662) to identify whether discrete amino acid substitutions may influence clinical phenotypes, survival and response to treatments in ...