Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Cassandra M, Wilkinson"'
Publikováno v:
PLoS ONE, Vol 18, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/c4b4f401fa86403d9be3a30e1b70edaf
Publikováno v:
Brain Hemorrhages, Vol 2, Iss 1, Pp 34-48 (2021)
As with ischemic and traumatic brain injury, raised intracranial pressure (ICP) is a common life-threatening complication of intracerebral hemorrhage (ICH). Elevated ICP can lead to cerebral ischemia, impaired cerebrospinal fluid flow, and brain hern
Externí odkaz:
https://doaj.org/article/43bfc3a0cefc484a9a763bb52034d42b
Autor:
Anna C. J. Kalisvaart, Cassandra M. Wilkinson, Sherry Gu, Tiffany F. C. Kung, Jerome Yager, Ian R. Winship, Frank K. H. van Landeghem, Frederick Colbourne
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury or death following severe stroke. Compensatory mechanisms include reduced cerebral blood and cerebrospinal fluid volumes, but these often fail to p
Externí odkaz:
https://doaj.org/article/0cfda1b4ad5d4c7287732a62aeecb83d
Autor:
Cassandra M. Wilkinson, Aristeidis H. Katsanos, Noam H. Sander, Tiffany F. C. Kung, Frederick Colbourne, Ashkan Shoamanesh
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Patients with intracerebral hemorrhage (ICH) are at increased risk for major ischemic cardiovascular and cerebrovascular events. However, the use of preventative antithrombotic therapy can increase the risk of ICH recurrence and worsen ICH-related ou
Externí odkaz:
https://doaj.org/article/fa014dc62ca546f7ac2c6c3055ec5a12
Autor:
Tiffany F C Kung, Cassandra M Wilkinson, Christine A Dirks, Glen C Jickling, Frederick Colbourne
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252584 (2021)
Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks the sulfonylurea 1 transient receptor potential melastatin 4 (Sur1
Externí odkaz:
https://doaj.org/article/aa5fe3b5564147809f58863890600c95
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215952 (2019)
The sulfonylurea 1 transient receptor potential melastatin 4 (Sur1-Trpm4) receptor is selectively expressed after intracerebral hemorrhage (ICH). This upregulation contributes to increases in intracellular sodium. Water follows sodium through aquapor
Externí odkaz:
https://doaj.org/article/30070899bae74e628c9829f93717a9a4
Autor:
Cassandra M Wilkinson, Brittany A Fedor, Jasmine R Aziz, Colby A Nadeau, Paul S Brar, Julia J A Clark, Frederick Colbourne
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210660 (2019)
After intracerebral hemorrhage (ICH), brain edema commonly occurs and can cause death. Along with edema, there are significant alterations in the concentrations of key ions such as sodium, potassium, and chloride, which are essential to brain functio
Externí odkaz:
https://doaj.org/article/08de905618234beb9e0ffc55ca3cecd2
Autor:
Frank van Landeghem, Cassandra M. Wilkinson, Anna C J Kalisvaart, Sherry Gu, Ian R. Winship, Jerome Y. Yager, Frederick Colbourne, Tiffany F. C. Kung
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury or death following severe stroke. Compensatory mechanisms include reduced cerebral blood and cerebrospinal fluid volumes, but these often fail to prevent ra
Autor:
Cassandra M Wilkinson, Jennifer I Burrell, Jeyaram Thangeswaran, Noman Ishaque, Paige Fairall, Mahesh P Kate, Kyle E Mathewson, Brian H Buck
Publikováno v:
Stroke. 53
Accurate and timely prehospital stroke diagnosis and detection of large vessel occlusion (LVO) are essential to ensure stroke patients are transported to hospitals that offer emergent reperfusion therapies. However, symptom based prehospital stroke s
Autor:
Cassandra M. Wilkinson, Tiffany F. C. Kung, Frederick Colbourne, Christine A. Dirks, Glen C. Jickling
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252584 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252584 (2021)
Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks the sulfonylurea 1 transient receptor potential melastatin 4 (Sur1